Search Results - "Nazzal, Lama"

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    The Microbiome and Uremic Solutes by Zaidan, Nadim, Nazzal, Lama

    Published in Toxins (30-03-2022)
    “…Uremic retention solutes, especially the protein-bound compounds, are toxic metabolites, difficult to eliminate with progressive renal functional decline. They…”
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    Journal Article
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    The role of the microbiome in kidney stone formation by Mehta, Mansi, Goldfarb, David S, Nazzal, Lama

    “…Abstract Nephrolithiasis is a complex disease of worldwide prevalence that is influenced by both genetic and environmental factors. About 75% of kidney stones…”
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    Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease by Liu, Menghan, Devlin, Joseph C, Hu, Jiyuan, Volkova, Angelina, Battaglia, Thomas W, Ho, Melody, Asplin, John R, Byrd, Allyson, Loke, P'ng, Li, Huilin, Ruggles, Kelly V, Tsirigos, Aristotelis, Blaser, Martin J, Nazzal, Lama

    Published in eLife (26-03-2021)
    “…Over-accumulation of oxalate in humans may lead to nephrolithiasis and nephrocalcinosis. Humans lack endogenous oxalate degradation pathways (ODP), but…”
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    Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist by Daniel, Steven L, Moradi, Luke, Paiste, Henry, Wood, Kyle D, Assimos, Dean G, Holmes, Ross P, Nazzal, Lama, Hatch, Marguerite, Knight, John

    Published in Applied and environmental microbiology (26-08-2021)
    “…Oxalobacter formigenes, a unique anaerobic bacterium that relies solely on oxalate for growth, is a key oxalate-degrading bacterium in the mammalian intestinal…”
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    Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion by Nazzal, Lama, Francois, Fritz, Henderson, Nora, Liu, Menghan, Li, Huilin, Koh, Hyunwook, Wang, Chan, Gao, Zhan, Perez, Guillermo Perez, Asplin, John R., Goldfarb, David S, Blaser, Martin J

    Published in Scientific reports (12-08-2021)
    “…The incidence of kidney stones is increasing in the US population. Oxalate, a major factor for stone formation, is degraded by gut bacteria reducing its…”
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    Comparative prevalence of Oxalobacter formigenes in three human populations by PeBenito, Amanda, Nazzal, Lama, Wang, Chan, Li, Huilin, Jay, Melanie, Noya-Alarcon, Oscar, Contreras, Monica, Lander, Orlana, Leach, Jeff, Dominguez-Bello, Maria Gloria, Blaser, Martin J.

    Published in Scientific reports (24-01-2019)
    “…There has been increasing interest in the human anaerobic colonic bacterium Oxalobacter formigenes because of its ability to metabolize oxalate, and its…”
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    Oxalobacter formigenes-associated host features and microbial community structures examined using the American Gut Project by Liu, Menghan, Koh, Hyunwook, Kurtz, Zachary D, Battaglia, Thomas, PeBenito, Amanda, Li, Huilin, Nazzal, Lama, Blaser, Martin J

    Published in Microbiome (25-08-2017)
    “…Increasing evidence shows the importance of the commensal microbe Oxalobacter formigenes in regulating host oxalate homeostasis, with effects against calcium…”
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    MesoTIPS: Combined approach for the treatment of portal hypertension secondary to portal vein thrombosis – A brief report by Chamsuddin, Abbas, Nazzal, Lama, Heffron, Thomas, Gaber, Osama, Achou, Raja, Martin, LouisG

    “…Introduction: We describe a technique we call “Meso-transjugular intrahepatic portosystemic shunt (MTIPS)” for relief of portal hypertension secondary to…”
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    MesoTIPS: Combined Approach for the Treatment of Portal Hypertension Secondary to Portal Vein Thrombosis – A Brief Report by Chamsuddin, Abbas, Nazzal, Lama, Heffron, Thomas, Gaber, Osama, Achou, Raja, Martin, Louis G.

    Published in Arab Journal of Interventional Radiology (01-01-2017)
    “…Abstract Introduction: We describe a technique we call “Meso-transjugular intrahepatic portosystemic shunt (MTIPS)” for relief of portal hypertension secondary…”
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    Journal Article
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    Enteric hyperoxaluria: role of microbiota and antibiotics by Liu, Menghan, Nazzal, Lama

    “…PURPOSE OF REVIEWEnteric hyperoxaluria is commonly observed in malabsorptive conditions including Roux en Y gastric bypass (RYGB) and inflammatory bowel…”
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    Enteric hyperoxaluria: an important cause of end-stage kidney disease by Nazzal, Lama, Puri, Sonika, Goldfarb, David S

    Published in Nephrology, dialysis, transplantation (01-03-2016)
    “…Hyperoxaluria is a frequent complication of inflammatory bowel diseases, ileal resection and Roux-en-Y gastric bypass and is well-known to cause…”
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    The Crystallization of Monosodium Urate by Martillo, Miguel A., Nazzal, Lama, Crittenden, Daria B.

    Published in Current rheumatology reports (01-02-2014)
    “…Gout is a common crystal-induced arthritis, in which monosodium urate (MSU) crystals precipitate within joints and soft tissues and elicit an inflammatory…”
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    Oxalate homeostasis by Ermer, Theresa, Nazzal, Lama, Tio, Maria Clarissa, Waikar, Sushrut, Aronson, Peter S., Knauf, Felix

    Published in Nature reviews. Nephrology (01-02-2023)
    “…Oxalate homeostasis is maintained through a delicate balance between endogenous sources, exogenous supply and excretion from the body. Novel studies have shed…”
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