Search Results - "Nazir, Zarghun"

Catalytic Asymmetric Reduction of a 3,4-Dihydroisoquinoline for the Large-Scale Production of Almorexant: Hydrogenation or Transfer Hydrogenation? by Verzijl, Gerard K. M, de Vries, André H. M, de Vries, Johannes G, Kapitan, Peter, Dax, Thomas, Helms, Matthias, Nazir, Zarghun, Skranc, Wolfgang, Imboden, Christoph, Stichler, Juergen, Ward, Richard A, Abele, Stefan, Lefort, Laurent

“…Several methods are presented for the enantioselective synthesis of the tetrahydroisoquinoline core of almorexant (ACT-078573A), a dual orexin receptor…”
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Cleavage of Phosphodiesters and of DNA by a Bis(guanidinium)naphthol Acting as a Metal-Free Anion Receptor by Ullrich, Stefan, Nazir, Zarghun, Büsing, Arne, Scheffer, Ute, Wirth, Daniela, Bats, Jan W., Dürner, Gerd, Göbel, Michael W.

“…Phosphoric acid diesters form anions at neutral pH. As a result of charge repulsion they are notoriously resistant to hydrolysis. Nucleophilic attack, however,…”
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