Search Results - "Nazarov, Igor B"

Dual Mode of Mitochondrial ROS Action during Reprogramming to Pluripotency by Skvortsova, Elena V., Nazarov, Igor B., Tomilin, Alexey N., Sinenko, Sergey A.

“…Essential changes in cell metabolism and redox signaling occur during the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). In this…”
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Partially Assembled Nucleosome Structures at Atomic Detail by Rychkov, Georgy N., Ilatovskiy, Andrey V., Nazarov, Igor B., Shvetsov, Alexey V., Lebedev, Dmitry V., Konev, Alexander Y., Isaev-Ivanov, Vladimir V., Onufriev, Alexey V.

“…The evidence is now overwhelming that partially assembled nucleosome states (PANS) are as important as the canonical nucleosome structure for the understanding…”
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Positioning of chromosomes in human spermatozoa is determined by ordered centromere arrangement by Mudrak, Olga S, Nazarov, Igor B, Jones, Estella L, Zalensky, Andrei O

“…The intranuclear positioning of chromosomes (CHRs) is a well-documented fact; however, mechanisms directing such ordering remain unclear. Unlike somatic cells,…”
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Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration by Nazarov, Igor B, Zilov, Danil S, Gordeev, Mikhail N, Potapenko, Evgenii V, Yeremenko, Nataliya, Tomilin, Alexey N

“…BOB1, a mammalian lymphocyte-specific transcriptional coactivator of the transcription factors OCT1 and OCT2 (OCT1/2), plays important roles in normal immune…”
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The angiotensin converting enzyme I/D polymorphism in Russian athletes by Nazarov, I B, Woods, D R, Montgomery, H E, Shneider, O V, Kazakov, V I, Tomilin, N V, Rogozkin, V A

“…The deletion (D) allele of the human ACE gene is associated with higher ACE activity than the insertion (I) allele. There is controversy as to whether the ACE…”
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hnRNP‐K Targets Open Chromatin in Mouse Embryonic Stem Cells in Concert with Multiple Regulators by Bakhmet, Evgeny I., Nazarov, Igor B., Gazizova, Adel R., Vorobyeva, Nadezhda E., Kuzmin, Andrey A., Gordeev, Mikhail N., Sinenko, Sergey A., Aksenov, Nikolai D., Artamonova, Tatyana O., Khodorkovskii, Mikhail A., Alenina, Natalia, Onichtchouk, Daria, Wu, Guangming, Schöler, Hans R., Tomilin, Alexey N.

“…The transcription factor Oct4 plays a key regulatory role in the induction and maintenance of cellular pluripotency. In this article, we show that ubiquitous…”
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Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus by Siino, Joseph S, Nazarov, Igor B, Svetlova, Maria P, Solovjeva, Lioudmila V, Adamson, Roger H, Zalenskaya, Irina A, Yau, Peter M, Morton Bradbury, E, Tomilin, Nikolai V

“…The Ser-139 phosphorylated form of replacement histone H2AX (γ-H2AX) is induced within large chromatin domains by double-strand DNA breaks (DSBs) in mammalian…”
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Sperm Chromatin Released by Nucleases by Nazarov, Igor B., Shlyakhtenko, Luda S., Lyubchenko, Yuri L., Zalenskaya, Irina A., Zalensky, Andrei O.

“…In human spermatozoa, 15-20% of histones are retained in the nucleus to coexist with protamines. Hypothetically, nucleohistone regions of sperm chromatin mark…”
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End‐joining of reconstituted histone H2AX‐containing chromatin in vitro by soluble nuclear proteins from human cells by Siino, Joseph S, Nazarov, Igor B, Zalenskaya, Irina A, Yau, Peter M, Bradbury, E.Morton, Tomilin, Nikolai V

“…Non‐homologous end‐joining is an important pathway for the repair of DNA double‐strand breaks. This type of DNA break is followed by the rapid phosphorylation…”
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