Search Results - "Naylor, Ruth L"

A Discrete Domain of the Human TrkB Receptor Defines the Binding Sites for BDNF and NT-4 by Naylor, Ruth L, Robertson, Alan G.S, Allen, Shelley J, Sessions, Richard B, Clarke, Anthony R, Mason, Grant G.F, Burston, Judy J, Tyler, Sue J, Wilcock, Gordon K, Dawbarn, David

“…TrkB is a member of the Trk family of tyrosine kinase receptors. In vivo, the extracellular region of TrkB is known to bind, with high affinity, the…”
Get full text

Specificity in Trk Receptor:Neurotrophin Interactions: The Crystal Structure of TrkB-d5 in Complex with Neurotrophin-4/5 by Banfield, Mark J, Naylor, Ruth L, Robertson, Alan G.S, Allen, Shelley J, Dawbarn, David, Brady, R.Leo

“…Background: The binding of neurotrophin ligands to their respective Trk cellular receptors initiates intracellular signals essential for the growth and…”
Get full text

Identification and Structure of the Nerve Growth Factor Binding Site on TrkA by Robertson, Alan G.S., Banfield, Mark J., Allen, Shelley J., Dando, Julie A., Mason, Grant G.F., Tyler, Sue J., Bennett, Gavin S., Brain, Susan D., Clarke, Anthony R., Naylor, Ruth L., Wilcock, Gordon K., Brady, R.Leo, Dawbarn, David

“…Nerve growth factor (NGF) is involved in the development and maintenance of the nervous system and has been implicated as a possible therapeutic target…”
Get full text

Specificity in Trk Receptor:Neurotrophin Interactions by Banfield, Mark J, Naylor, Ruth L, Robertson, Alan G.S, Allen, Shelley J, Dawbarn, David, Brady, R.Leo

Get full text

Identification of syntaxin 1A as a novel binding protein for presenilin-1 by Smith, Stephanie K.F, Anderson, Howard A, Yu, Gang, Robertson, Alan G.S, Allen, Shelley J, Tyler, Sue J, Naylor, Ruth L, Mason, Grant, Wilcock, Gordon W, Roche, Paul A, Fraser, Paul E, Dawbarn, David

“…Mutations in the presenilin 1 gene have been shown to result in Alzheimer’s disease. Presenilin 1 is a multi-transmembrane protein with a large hydrophilic…”
Get full text