Search Results - "Nayebi, Alireza Mohajjel"
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The Novel Pharmacological Approaches to Coumestrol: Focusing on the Psychiatric and Neurological Benefits and the Newly Identified Receptor Interactions
Published in Pharmaceutical Sciences (01-04-2023)“…For years, the health benefits of coumestrol (CMT) have been investigated by researchers around the world. Anti-oxidative properties of the phytoestrogen which…”
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Coumestrol alleviates oxidative stress, apoptosis and cognitive impairments through hippocampal estrogen receptor-beta in male mouse model of chronic restraint stress
Published in Pharmaceutical Sciences (01-04-2022)“…Background: Coumestrol is well-known as a natural estrogen receptor-beta modulator. Since the role of estrogen receptors in controlling stressful situations…”
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Venlafaxine-Induced Cytotoxicity Towards Isolated Rat Hepatocytes Involves Oxidative Stress and Mitochondrial/Lysosomal Dysfunction
Published in Advanced pharmaceutical bulletin (01-12-2016)“…Purpose: Depression is a public disorder worldwide. Despite the widespread use of venlafaxine in the treatment of depression, it has been associated with the…”
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Cardioprotective Effect of Grape Seed Extract on Chronic Doxorubicin-Induced Cardiac Toxicity in Wistar Rats
Published in Advanced pharmaceutical bulletin (01-09-2016)“…Purpose: The aim of the present study was to determine the ability of grape seed extract (GSE) as a powerful antioxidant in preventing adverse effect of…”
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Short-Term Treatment with Silymarin Improved 6-OHDA-Induced Catalepsy and Motor Imbalance in Hemi-Parkisonian Rats
Published in Advanced pharmaceutical bulletin (01-11-2015)“…Purpose: Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by disabling motor abnormalities, which include tremor, muscle…”
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8-OH-DPAT (5-HT1A agonist) Attenuates 6-Hydroxy- dopamine-induced catalepsy and Modulates Inflammatory Cytokines in Rats
Published in Iranian journal of basic medical sciences (01-12-2013)“…Neuroinflammation in Parkinson disease (PD) is associated with glial cells activation and production of different inflammatory cytokines. In this study, we…”
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Retraction Notice to “Silymarin prevents apoptosis through inhibiting the Bax/caspase-3 expression and suppresses toll like receptor-4 pathway in the SNc of 6-OHDA intoxicated rats” [Biomed. Pharmacother. 104 (2018) 127–136]
Published in Biomedicine & pharmacotherapy (01-01-2024)Get full text
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Mechanistic Approach for Toxic Effects of Bupropion in Primary Rat Hepatocytes
Published in Drug research (01-04-2017)“…Bupropion is a widely prescribed antidepressant/smoke cessation drug. However, hepatotoxicity is one of its side effects reported in some recipients. The…”
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Comparison of the Analgesic Effect of Diclofenac Sodium-Eudragit® RS100 Solid Dispersion and Nanoparticles Using Formalin Test in the Rats
Published in Advanced pharmaceutical bulletin (01-03-2015)“…Purpose: In this study the intensity and duration of analgesic effect of diclofenac Na - Eudragit ® RS100 solid dispersion and nanoparticles were evaluated by…”
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Testosterone Replacement Attenuates Haloperidol-Induced Catalepsy in Male Rats
Published in Advanced pharmaceutical bulletin (2014)“…Purpose: Parkinson’s disease (PD) is a progressive neurodegenerative disease. Recent studies have indicated a higher prevalence of PD in male gender…”
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In vitro and in vivo evaluation of the mechanisms of citalopraminduced hepatotoxicity
Published in Archives of pharmacal research (01-11-2017)“…Even though citalopram is commonly used inpsychiatry, there are several reports on its toxic effects. So,the current study was designed to elucidate the…”
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Fluoxetine Improves the Effect of Levodopa on 6-Hydroxy Dopamine-Induced Motor Impairments in Rats
Published in Advanced pharmaceutical bulletin (2012)“…Purpose: Long term L-DOPA therapy in Parkinson’s disease is associated with troublesome motor fluctuations such as L -DOPA Induced dyskinesia and wearing off…”
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Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats
Published in Life sciences (1973) (15-07-2016)“…Doxorubicin (DOX)-induced cardiotoxicity is well-known as a serious complication of chemotherapy in patients with cancer. It is unknown whether crocin (CRO),…”
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Pre-treatment with silymarin reduces brain myeloperoxidase activity and inflammatory cytokines in 6-OHDA hemi-parkinsonian rats
Published in Neuroscience letters (25-10-2013)“…•Intra-SNc injection of 6-OHDA induce catalepsy in rats.•Silymarin prevented from 6-OHDA induce catalepsy.•Brain MPO activity and CSF levels of TNF-α and IL-6…”
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Cardioprotective Effect of Phenytoin on Doxorubicin-induced Cardiac Toxicity in a Rat Model
Published in Journal of cardiovascular pharmacology (01-03-2016)“…Doxorubicin (DOX) is an effective anticancer agent, but adverse cardiotoxic effects limit its use. Compounds reducing DOX cardiotoxicity could improve its…”
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Effect of Acute and Chronic Administration of Carbamazepine on Cisplatin-Induced Hyperalgesia in Rats
Published in Jundishapur journal of natural pharmaceutical products (04-01-2012)Get full text
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Testosterone ameliorates streptozotocin-induced memory impairment in male rats
Published in Acta pharmacologica Sinica (01-06-2014)“…Aim: To study the effects of testosterone on streptozotocin (STZ)-induced memory impairment in male rats. Methods: Adult male Wistar rats were…”
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Effect of WR-1065 on 6-hydroxydopamine-induced catalepsy and IL-6 level in rats
Published in Iranian journal of basic medical sciences (01-05-2016)“…Neuroinflammation and oxidative stress play a key role in pathogenesis of Parkinson's disease (PD). In the present study we investigated the effect of reactive…”
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Targeted Co-Delivery of Docetaxel and cMET siRNA for Treatment of Mucin1 Overexpressing Breast Cancer Cells
Published in Advanced pharmaceutical bulletin (01-08-2018)“…According to the study by Jadidi et al.,22 releasing of the siRNA from chitosan-lactate NPs was gradually continued up to 72nd hour and then reached to the…”
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Effects of Heracleum persicum Hydroalcoholic Extract on Insulin, Serum Anti-Oxidant Enzymes, Glucose, and Lipid Profiles in Alloxan-Induced Diabetic Rats
Published in Iranian journal of medical sciences (01-05-2020)“…( ) is a medicinal herb used in Iranian traditional medicine for its anti-toxic property. It is commonly consumed in the form of food additives and as a…”
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