Search Results - "Nayak, Pawan G."

Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice by Bansal, Punit, Paul, Piya, Mudgal, Jayesh, G. Nayak, Pawan, Thomas Pannakal, Steve, Priyadarsini, K.I., Unnikrishnan, M.K.

“…The present study describes the antidiabetic effect of the flavonoid rich fraction of Pilea microphylla (PM1). HPLC characterization of PM1 revealed the…”
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An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells by Reddy, Neetinkumar D., Shoja, M.H., Biswas, Subhankar, Nayak, Pawan G., Kumar, Nitesh, Rao, C. Mallikarjuna

“…Multiple genetic mutations along with unusual epigenetic modifications play a major role in cancer development. Histone deacetylase (HDAC) enzyme…”
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Mechanisms behind the pharmacological application of biochanin-A: a review [version 1; peer review: 1 approved with reservations] by Anuranjana, P.V., Beegum, Fathima, K.P, Divya, George, Krupa Thankam, Viswanatha, G.L., Nayak, Pawan G., Kanwal, Abhinav, Kishore, Anoop, Shenoy, Rekha R., Nandakumar, K.

“…This review was aimed at summarizing the cellular and molecular mechanisms behind the various pharmacological actions of biochanin-A. Many studies have been…”
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Investigation of Sesamol on Myeloperoxidase and Colon Morphology in Acetic Acid-Induced Inflammatory Bowel Disorder in Albino Rats by Rao, C. Mallikarjuna, Nayak, Pawan G., Mathew, Geetha, Kovelamudi, Hemalatha, Kondamudi, Phani Krishna, Shenoy, Rekha R.

“…Background. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of gastrointestinal tract of immune, genetic, and environmental origin. In the…”
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Evaluation of in vitro antioxidant and in vivo analgesic potential of Terminalia paniculata aqueous bark extract by Talwar, Sahil, Nayak, Pawan G, Mudgal, Jayesh, Paul, Piya, Bansal, Punit, Nandakumar, Krishnadas

“…The Terminalia genus includes plants that are used in a variety of food, nutritional products, and traditional medicines. Aqueous bark extract of Terminalia…”
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Protective effect of β-glucan on Poly(I:C)-induced acute lung injury/inflammation: Therapeutic implications of viral infections in the respiratory system by Tirunavalli, Satya Krishna, Pramatha, Shashidhar, Eedara, Abhisheik Chowdary, Walvekar, Komal Paresh, Immanuel, Christiana, Potdar, Pooja, Nayak, Pawan G., Chamallamudi, Mallikarjuna Rao, Sistla, Ramakrishna, Chilaka, Sabarinadh, Andugulapati, Sai Balaji

“…Acute lung inflammation, particularly acute respiratory distress syndrome (ARDS), is caused by a variety of pathogens including bacteria and viruses. β-Glucans…”
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Impact of caffeic acid on aluminium chloride-induced dementia in rats by Khan, Kafeel A., Kumar, Nitesh, Nayak, Pawan G., Nampoothiri, Madhavan, Shenoy, Rekha R., Krishnadas, Nandakumar, Rao, C. Mallikarjuna, Mudgal, Jayesh

“…Objective Literature favours the in vitro neuroprotective role of caffeic acid, a naturally derived polyphenolic compound. This study was aimed to investigate…”
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Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells by Shoja, M.H., Reddy, Neetinkumar D., Nayak, Pawan G., Srinivasan, K.K., Rao, C. Mallikarjuna

“…Glycosmis pentaphylla (Retz.) DC belonging to the family Rutaceae has been traditionally used for the treatment of rheumatism, anaemia, jaundice, skin…”
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Sesamol Treatment Reduces Plasma Cholesterol and Triacylglycerol Levels in Mouse Models of Acute and Chronic Hyperlipidemia by Kumar, Nitesh, Mudgal, Jayesh, Parihar, Vipan K., Nayak, Pawan G., Kutty, N. Gopalan, Rao, C. Mallikarjuna

“…The active constituents of Sesamum indicum , sesamin and sesamolin, have already been explored for hypolipidemic action. In this study we have explored the…”
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Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats by Ramalingayya, Grandhi Venkata, Cheruku, Sri Pragnya, Nayak, Pawan G, Kishore, Anoop, Shenoy, Rekha, Rao, Chamallamudi Mallikarjuna, Krishnadas, Nandakumar

“…Doxorubicin (DOX) is the most widely used broad-spectrum anticancer agent, either alone or in combination, for most cancers including breast cancer. Long-term…”
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Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts by Nayak, Pawan G., Paul, Piya, Bansal, Punit, Kutty, Nampurath Gopalan, Pai, Karkala Sreedhara Ranganath

“…Objectives Exposure to toxicants like doxorubicin (Dox) damages cellular components by generating reactive oxygen species (ROS). This can be attenuated using…”
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Anti-inflammatory activity of Terminalia paniculata bark extract against acute and chronic inflammation in rats by Talwar, Sahil, Nandakumar, K., Nayak, Pawan G., Bansal, Punit, Mudgal, Jayesh, Mor, Vijay, Rao, Chamallamudi Mallikarjuna, Lobo, Richard

“…Terminalia paniculata Roxb. (Family-Combretaceae) is a wild tree commonly used in traditional ayurvedic medicine for the treatment of inflammation of parotid…”
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Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo by Ramalingayya, Grandhi Venkata, Nayak, Pawan G, Shenoy, Rekha R, Rao, Chamallamudi Mallikarjuna, Nandakumar, Krishnadas

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Sodium valproate enhances doxorubicin-induced cognitive dysfunction in Wistar rats by Verma, Thaneshwar, Mallik, Sanchari Basu, Ramalingayya, G.V., Nayak, Pawan G., Kishore, Anoop, Pai, K. Sreedhara R., Nandakumar, Krishnadas

“…Increasing number of scientific reports have highlighted the role of histone acetylation/deacetylation in neurodegenerative conditions, including…”
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Combined Administration of Monosodium Glutamate and High Sucrose Diet Accelerates the Induction of Type 2 Diabetes, Vascular Dysfunction, and Memory Impairment in Rats by Saikrishna, Kaja, Kumari, Ringu, Chaitanya, Kantamaneni, Biswas, Subhankar, Nayak, Pawan G, Mudgal, Jayesh, Kishore, Anoop, Nandakumar, Krishnadas

“…In this study, we aimed to develop an experimental animal model for type 2 diabetes mellitus (T2DM) using a combination of monosodium glutamate (MSG) and high…”
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Click Chemistry Approach for Bis-Chromenyl Triazole Hybrids and Their Antitubercular Activity by Naik, Reshma J., Kulkarni, Manohar V., Sreedhara Ranganath Pai, K., Nayak, Pawan G.

“…1,4‐Disubstituted bis‐chromenyl triazole hybrids 5a–m have been synthesized in a three‐step reaction sequence from 4‐(bromomethyl)‐2H‐chromen‐2‐ones 3a–m. The…”
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Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats by Shenoy, Rekha R., Sudheendra, Arun T., Nayak, Pawan G., Paul, Piya, Kutty, N. Gopalan, Rao, C. Mallikarjuna

“…The seeds of Sesamum indicum Linn. (Pedaliaceae) has been used traditionally for the treatment of wounds in Buldhana district of Maharashtra state. Sesamol is…”
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In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer by Shoja, M.H., Reddy, Neetinkumar D., Nayak, Pawan G., Biswas, Subhankar, Srinivasan, K.K., Rao, C. Mallikarjuna

“…Glycosmis pentaphylla (Retz.) DC (Rutaceae) has been traditionally used for the treatment of rheumatism, cancer, liver disorders, inflammation etc. The present…”
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In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma by Reddy, Neetinkumar D., Shoja, M.H., Jayashree, B.S., Nayak, Pawan G., Kumar, Nitesh, Prasad, V. Ganga, Pai, K. Sreedhara R., Rao, C. Mallikarjuna

“…[Display omitted] •Synthesized NMJ series hydroxamates exhibited anti-cancer activity.•All compounds inhibited whole cell HDAC enzyme in HCT 116 colon cancer…”
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Novel Indole-Quinazolinone Based Amides as Cytotoxic Agents by Gokhale, Nikhila, Panathur, Naveen, Dalimba, Udayakumar, Nayak, Pawan G., Pai, K. Sreedhar Ranganath

“…Indole‐quinazolinone hybrids with active amides were synthesized, characterized, and assessed for their cytotoxicity. Two molecules displayed substantial…”
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