Search Results - "Nayak, Komal M"
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DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development
Published in Gut (01-01-2019)“…Human intestinal epithelial organoids (IEOs) are increasingly being recognised as a highly promising translational research tool. However, our understanding of…”
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DNA methylation analysis in the intestinal epithelium-effect of cell separation on gene expression and methylation profile
Published in PloS one (08-02-2013)“…Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic studies. However, to…”
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An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
Published in Nature microbiology (01-02-2019)Get full text
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DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2018)“…We analyzed DNA methylation patterns and transcriptomes of primary intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel…”
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An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
Published in Nature microbiology (01-02-2019)“…Enteroviruses comprise a large group of mammalian pathogens that includes poliovirus. Pathology in humans ranges from sub-clinical to acute flaccid paralysis,…”
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Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived…”
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