Search Results - "Naya, F. J."

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1 by Musaro, A., McCullagh, K. J., Naya, F. J., Olson, E. N., Rosenthal, N.

“…Localized synthesis of insulin-like growth factors (IGFs) has been broadly implicated in skeletal muscle growth, hypertrophy and regeneration. Virally…”
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Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor by Naya, F J, Stellrecht, C M, Tsai, M J

“…The insulin gene is one of the best paradigms of tissue-specific gene expression. It is developmentally regulated and is expressed exclusively in the…”
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The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells by Mutoh, H, Naya, F J, Tsai, M J, Leiter, A B

“…The major epithelial cell types lining the intestine comprise a perpetually self-renewing population of cells that differentiate continuously from a stem cell…”
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Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor by Olson, Eric N, Naya, Francisco J, Black, Brian L, Wu, Hai, Bassel-Duby, Rhonda, Richardson, James A, Hill, Joseph A

“…The four MEF2 transcription factors (MEF2A, -B, -C, and -D) regulate differentiation and calcium-dependent gene expression in muscle cells. We generated mice…”
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MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation by Naya, Francisco J, Olson, Eric

“…Skeletal muscle development involves a multistep pathway in which mesodermal precursor cells are selected, in response to inductive cues, to form myoblasts…”
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Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35 by Owerbach, D., Naya, F. J., Tsai, M. J., Allander, S. V., Powell, D. R., Gabbay, K. H.

“…Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35. D Owerbach , F J…”
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Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway by Wu, Hai, Rothermel, Beverly, Kanatous, Shane, Rosenberg, Paul, Naya, Francisco J., Shelton, John M., Hutcheson, Kelley A., DiMaio, J.Michael, Olson, Eric N., Bassel-Duby, Rhonda, Williams, R.Sanders

“…Gene expression in skeletal muscles of adult vertebrates is altered profoundly by changing patterns of contractile work. Here we observed that the functional…”
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CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo by Passier, R, Zeng, H, Frey, N, Naya, F J, Nicol, R L, McKinsey, T A, Overbeek, P, Richardson, J A, Grant, S R, Olson, E N

“…Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly,…”
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Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo by Naya, Francisco J., Mercer, Brian, Shelton, John, Richardson, James A., Williams, R.Sanders, Olson, Eric N.

“…Adult skeletal muscle fibers can be categorized into fast and slow twitch subtypes based on specialized contractile and metabolic properties and on distinctive…”
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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice by Naya, F J, Huang, H P, Qiu, Y, Mutoh, H, DeMayo, F J, Leiter, A B, Tsai, M J

“…Candidate transcription factors involved in pancreatic endocrine development have been isolated using insulin gene regulation as a paradigm. The cell-type…”
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MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type by Wu, Hai, Naya, Francisco J., McKinsey, Timothy A., Mercer, Brian, Shelton, John M., Chin, Eva R., Simard, Alain R., Michel, Robin N., Bassel-Duby, Rhonda, Olson, Eric N., Williams, R.Sanders

“…Different patterns of motor nerve activity drive distinctive programs of gene transcription in skeletal muscles, thereby establishing a high degree of…”
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BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes by Peyton, Michael, Stellrecht, Christine M. M., Naya, Francisco J., Huang, Hsiang-Po, Samora, Patrick J., Tsai, Ming-Jer

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Loss of BETA2/NeuroD Leads to Malformation of the Dentate Gyrus and Epilepsy by Liu, Min, Pleasure, Samuel J., Collins, Abigail E., Noebels, Jeffrey L., Naya, Francesco J., Tsai, Ming-Jer, Lowenstein, Daniel H.

“…BETA2/NeuroD is a homologue of the Drosophila atonal gene that is widely expressed during development in the mammalian brain and pancreas. Although studies in…”
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Neuronal Basic Helix-Loop-Helix Proteins (NEX and BETA2/Neuro D) Regulate Terminal Granule Cell Differentiation in the Hippocampus by Schwab, Markus H, Bartholomae, Angelika, Heimrich, Bernd, Feldmeyer, Dirk, Druffel-Augustin, Silke, Goebbels, Sandra, Naya, Frank J, Zhao, Shanting, Frotscher, Michael, Tsai, Ming-Jer, Nave, Klaus-Armin

“…The transcription factors neuronal helix-loop-helix protein (NEX)/mammalian atonal homolog 2 (Math-2), BETA2/neuronal determination factor (NeuroD), and…”
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Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene by Naya, F J, Wu, C, Richardson, J A, Overbeek, P, Olson, E N

“…The four members of the MEF2 family of MADS-box transcription factors, MEF2-A, MEF2-B, MEF2-C and MEF2-D, are expressed in overlapping patterns in developing…”
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The Basic Helix-Loop-Helix Transcription Factor BETA2/NeuroD is Expressed in Mammalian Enteroendocrine Cells and Activates Secretin Gene Expression by Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.

“…The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp…”
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Analysis of candidate genes for susceptibility to type I diabetes: A case-control and family-association study of genes on chromosome 2q31-35 by OWERBACH, D, NAYA, F. J, TSAI, M.-J, ALLANDER, S. V, POWELL, D. R, GABBAY, K. H

“…Recent genome searches suggest a putative linkage of many loci to susceptibility to type I diabetes. The chromosome 2q31-35 region is reported to be linked to…”
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Distribution of R-cognin and choline acetyltransferase in the ganglion cell layer of developing chick neural retina by Dobi, E T, Naya, F J, Hausman, R E

“…Retina cognin, a cell membrane glycoprotein which mediates cell-cell recognition and adhesion in vitro, is initially present throughout the retina and becomes…”
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Myospryn Is a Direct Transcriptional Target for MEF2A That Encodes a Striated Muscle, α-Actinin-interacting, Costamere-localized Protein by Durham, Jennifer T., Brand, Ondra M., Arnold, Michael, Reynolds, Joseph G., Muthukumar, Lavanya, Weiler, Hartmut, Richardson, James A., Naya, Francisco J.

“…The full repertoire of proteins that comprise the striated muscle Z-disc and peripheral structures, such as the costamere, have yet to be discovered. Recent…”
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Calcineurin activation influences muscle phenotype in a muscle-specific fashion by Talmadge, Robert J, Otis, Jeffrey S, Rittler, Matthew R, Garcia, Nicole D, Spencer, Shelly R, Lees, Simon J, Naya, Francisco J

“…The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of…”
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