Search Results - "Navis, G. J"

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis by Hamming, I, Timens, W, Bulthuis, MLC, Lely, AT, Navis, GJ, van Goor, H

“…Severe acute respiratory syndrome (SARS) is an acute infectious disease that spreads mainly via the respiratory route. A distinct coronavirus (SARS‐CoV) has…”
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Use of maximal dosage renin-angiotensin-aldosterone system inhibitors in a real life population of complicated type 2 diabetes – contraindications and opportunities by Gant, C. M, Oosterwijk, M. M, Binnenmars, S. H, Navis, G. J, Haverkate, H, Bakker, S. J. L, Laverman, G. D

“…Abstract Objective Pharmacological inhibition of the renin-angiotensin-aldosterone-system (RAASi) is the cornerstone of hypertension treatment, renoprotection…”
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Renal ACE2 expression in human kidney disease by Lely, AT, Hamming, I, van Goor, H, Navis, GJ

“…Angiotensin‐converting enzyme 2 (ACE2) is a recently discovered homologue of angiotensin‐converting enzyme (ACE) that is thought to counterbalance ACE. ACE2…”
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Sodium intake affects urinary albumin excretion especially in overweight subjects by Verhave, J. C., Hillege, H. L., Burgerhof, J. G. M., Janssen, W. M. T., Gansevoort, R. T., Navis, G. J., Zeeuw, D., Jong, P. E.

“…Objectives.  To examine the relationship between sodium intake and urinary albumin excretion, being an established risk marker for later cardiovascular…”
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Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial by Kwakernaak, A J, Roksnoer, L C, Lambers Heerspink, H J, van den Berg-Garrelds, I, Lochorn, G A, van Embden Andres, J H, Klijn, M A, Kobori, H, Danser, A H J, Laverman, G D, Navis, G J

“…The combination of weight excess and hypertension significantly contributes to cardiovascular risk and progressive kidney damage. An unfavorable renal…”
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Body Mass Index and Glomerular Hyperfiltration in Renal Transplant Recipients: Cross‐Sectional Analysis and Long‐Term Impact by Bosma, R. J., Kwakernaak, A. J., Homan van der Heide, J. J., De Jong, P. E., Navis, G. J.

“…Obesity is a risk factor for renal graft loss. Higher body mass index (BMI) in native kidneys is associated with glomerular hyperfiltration. Whether higher BMI…”
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Hepatic Syndecan‐1 Changes Associate With Dyslipidemia After Renal Transplantation by Adepu, S., Katta, K., Tietge, U. J. F., Kwakernaak, A. J., Dam, W., van Goor, H., Dullaart, R. P. F., Navis, G. J., Bakker, S. J. L., van den Born, J.

“…Syndecan‐1 is a transmembrane heparan sulfate (HS) proteoglycan present on hepatocytes and involved in uptake of triglyceride‐rich lipoproteins via its HS…”
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Association of Complement C3 Gene Variants with Renal Transplant Outcome of Deceased Cardiac Dead Donor Kidneys by Damman, J., Daha, M. R., Leuvenink, H. G., van Goor, H., Hillebrands, J. L., Dijk, M. C. van, Hepkema, B. G., Snieder, H., Born, J. van den, de Borst, M. H., Bakker, S. J., Navis, G. J., Ploeg, R. J., Seelen, M. A.

“…Local renal complement activation by the donor kidney plays an important role in the pathogenesis of renal injury inherent to kidney transplantation…”
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Nephrectomy Elicits Impact of Age and BMI on Renal Hemodynamics: Lower Postdonation Reserve Capacity in Older or Overweight Kidney Donors by Rook, M., Bosma, R. J., Van Son, W. J., Hofker, H. S., Van Der Heide, J. J. Homan, Ter Wee, P. M., Ploeg, R. J., Navis, G. J.

“…Renal functional reserve could be relevant for the maintenance of renal function after kidney donation. Low‐dose dopamine induces renal vasodilation with a…”
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Analysis of C1q polymorphisms suggests association with systemic lupus erythematosus, serum C1q and CH50 levels and disease severity by Martens, H A, Zuurman, M W, de Lange, A H M, Nolte, I M, van der Steege, G, Navis, G J, Kallenberg, C G M, Seelen, M A, Bijl, M

“…Several findings link systemic lupus erythematosus (SLE) with C1q, the first molecule of the classical complement pathway. Polymorphisms of the C1qA gene are…”
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Predictive Capacity of Pre‐Donation GFR and Renal Reserve Capacity for Donor Renal Function After Living Kidney Donation by Rook, M., Hofker, H. S., Van Son, W. J., Homan van der Heide, J. J., Ploeg, R. J., Navis, G. J.

“…Kidney transplantation from living donors is important to reduce organ shortage. Reliable pre‐operative estimation of post‐donation renal function is…”
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polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus by Alkhalaf, A, Bakker, S. J. L, Bilo, H. J. G, Gans, R. O. B, Navis, G. J, Postmus, D, Forsblom, C, Groop, P. H, Vionnet, N, Hadjadj, S, Marre, M, Parving, H. H, Rossing, P, Tarnow, L

“…Aims/hypothesis Homozygosity for a five leucine repeat (5L-5L) in the carnosinase gene (CNDP1) has been found to be cross-sectionally associated with a low…”
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Former Smoking Is a Risk Factor for Chronic Kidney Disease After Lung Transplantation by Hellemons, M. E., Agarwal, P. K., van der Bij, W., Verschuuren, E. A. M., Postmus, D., Erasmus, M. E., Navis, G. J., Bakker, S. J. L.

“…Chronic kidney disease (CKD) is a common complication after lung transplantation (LTx). Smoking is a risk factor for many diseases, including CKD. Smoking…”
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Donor Kidney Adapts to Body Dimensions of Recipient: No Influence of Donor Gender on Renal Function After Transplantation by Tent, H., Lely, A. T., Toering, T. J., San Giorgi, M. R. M., Rook, M., Lems, S. P. M., Hepkema, B. G., Hofker, H. S., Ploeg, R. J., Homan van der Heide, J. J., Navis, G. J.

“…Female kidneys and kidneys from small donors have been suggested to perform worse after kidney transplantation. Here, we evaluate the impact of gender and body…”
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Effect of dexamethasone on perioperative renal function impairment during cardiac surgery with cardiopulmonary bypass by Loef, B.G., Henning, R.H., Epema, A.H., Rietman, G.W., van Oeveren, W., Navis, G.J., Ebels, T.

“…In cardiac surgery with cardiopulmonary bypass (CPB), corticosteroids are administered to attenuate the physiological changes caused by the systemic…”
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The Development of Intensive Care Unit Acquired Hypernatremia Is Not Explained by Sodium Overload or Water Deficit: A Retrospective Cohort Study on Water Balance and Sodium Handling by Navis, G. J., Kingma, W. Peter, Buter, Hanneke, IJzendoorn, M. C. O. van, Boerma, E. Christiaan

“…Background. ICU acquired hypernatremia (IAH, serum sodium concentration (sNa) ≥ 143 mmol/L) is mainly considered iatrogenic, induced by sodium overload and…”
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Receptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis by Martens, HA, Nienhuis, HLA, Gross, S, der Steege, G van, Brouwer, E, Berden, JHM, Sévaux, RGL de, Derksen, RHWM, Voskuyl, AE, Berger, SP, Navis, GJ, Nolte, IM, Kallenberg, CGM, Bijl, M

“…Objective: Interaction of advanced glycation end products (AGEs) with their receptors (RAGE) plays an important role in inflammation in auto-immune diseases…”
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Donor and Recipient Origin of Mesenchymal and Endothelial Cells in Chronic Renal Allograft Remodeling by Rienstra, H., Boersema, M., Onuta, G., Boer, M. W., Zandvoort, A., Van Riezen, M., Rozing, J., Van Goor, H., Navis, G. J., Popa, E. R., Hillebrands, J. L.

“…Chronic transplant dysfunction (CTD) is the leading cause for limited kidney graft survival. Renal CTD is characterized by interstitial and vascular remodeling…”
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Optimal dosing of renin-angiotensin-aldosterone system blockers for renal protection: a solved issue? by Laverman, G. D, Bakker, S. J. L, Navis, G. J

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Multimorbidity prevalence and patterns and their associations with health literacy among chronic kidney disease patients by Gurgel do Amaral, M. S., Reijneveld, S. A., Meems, L. M. G., Almansa, J., Navis, G. J., de Winter, A. F.

“…Background Health literacy is the ability to deal with information related to one’s health. Patients with low health literacy have poor disease-management…”
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