Search Results - "Naves, Lara M"

The Newly Synthesized Pyrazole Derivative 5-(1-(3 Fluorophenyl)-1H-Pyrazol-4-yl)-2H-Tetrazole Reduces Blood Pressure of Spontaneously Hypertensive Rats via NO/cGMO Pathway by Trindade, Neidiane R., Lopes, Paulo R., Naves, Lara M., Fajemiroye, James O., Alves, Pedro H., Amaral, Nathalia O., Lião, Luciano M., Rebelo, Ana C. S., Castro, Carlos H., Braga, Valdir A., Menegatti, Ricardo, Pedrino, Gustavo R.

“…The search for new antihypertensive drugs has grown in recent years because of high rate of morbidity among hypertensive patients and several side effects that…”
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Preclinical pharmacokinetics of a promising antineoplastic prototype piperazine-containing compound (LQFM018) in rats by a new LC-MS/MS bioanalytical method by Rodrigues, Andryne R., Rodrigues, Caroline R., Gomes, Sandro A., Marques, Stefanne M., Naves, Lara M., Pedrino, Gustavo R., de Oliveira-Neto, Jerônimo R., de Carvalho, Flávio S., Cruz, Alessandro, Lião, Luciano M., Menegatti, Ricardo, Carlos da Cunha, Luiz

“…•High throughput and sensitive bioanalytical method for the LQFM018 quantification.•First and reliable determination of main pharmacokinetic LQFM018…”
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Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II–Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity by Guimarães, Drielle D, Cruz, Josiane C, Carvalho-Galvão, Alynne, Zhuge, Zhengbing, Marques, Stefanne M, Naves, Lara M, Persson, A. Erik G, Weitzberg, Eddie, Lundberg, Jon O, Balarini, Camille M, Pedrino, Gustavo R, Braga, Valdir A, Carlström, Mattias

“…Several experimental and clinical studies have shown that dietary nitrate supplementation can increase nitric oxide bioavailability. In the oral cavity,…”
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p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats by Dutra, João B.R., Lacerda, Ismaley S., Nunes, Allancer D.C., Bessa, Amanda S.M., Jesus, Érika F., Pontes, Carolina N.R., Naves, Lara M., Pedrino, Gustavo R., Mendes, Elizabeth P., Fraga-Silva, Rodrigo A., Costa-Fraga, Fabiana P., Stergiopulos, Nikos, Kangussu, Lucas M., Faraco, André A.G., Ferreira, Anderson J., Castro, Carlos H.

“…Diminazene aceturate, a putative ACE2 activator, is susceptible to cleavage resulting in the formation of p-aminobenzamidine (PAB). This study aimed to…”
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Involvement of the gabaergic, serotonergic and glucocorticoid mechanism in the anxiolytic-like effect of mastoparan-L by Silva, Osmar N., Franco, Octavio L., Neves, Bruno J., Morais, Álice Cristina B., De Oliveira Neto, Jeronimo R., da Cunha, Luiz Carlos, Naves, Lara M., Pedrino, Gustavo R., Costa, Elson A., Fajemiroye, James O.

“…Mastoparan-L (mast-L) is a cell-penetrating tetradecapeptide and stimulator of monoamine exocytosis. In the present study, we evaluated the anxiolytic-like…”
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Efferent pathways in sodium overload-induced renal vasodilation in rats by Amaral, Nathalia O, de Oliveira, Thiago S, Naves, Lara M, Filgueira, Fernando P, Ferreira-Neto, Marcos L, Schoorlemmer, Gerard H M, de Castro, Carlos H, Freiria-Oliveira, André H, Xavier, Carlos H, Colugnati, Diego B, Rosa, Daniel A, Blanch, Graziela T, Borges, Clayton L, Soares, Célia M A, Reis, Angela A S, Cravo, Sergio L, Pedrino, Gustavo R

“…Hypernatremia stimulates the secretion of oxytocin (OT), but the physiological role of OT remains unclear. The present study sought to determine the…”
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The Newly Synthesized Pyrazole Derivative 5-(1-(3 Fluorophenyl)-1 H -Pyrazol-4-yl)-2 H -Tetrazole Reduces Blood Pressure of Spontaneously Hypertensive Rats via NO/cGMO Pathway by Trindade, Neidiane R, Lopes, Paulo R, Naves, Lara M, Fajemiroye, James O, Alves, Pedro H, Amaral, Nathalia O, Lião, Luciano M, Rebelo, Ana C S, Castro, Carlos H, Braga, Valdir A, Menegatti, Ricardo, Pedrino, Gustavo R

“…The search for new antihypertensive drugs has grown in recent years because of high rate of morbidity among hypertensive patients and several side effects that…”
Get full text