Search Results - "Naveen Kumar, C. N"

Discovery of Imidazo[1,2‑a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis by Tantry, Subramanyam J, Markad, Shankar D, Shinde, Vikas, Bhat, Jyothi, Balakrishnan, Gayathri, Gupta, Amit K, Ambady, Anisha, Raichurkar, Anandkumar, Kedari, Chaitanyakumar, Sharma, Sreevalli, Mudugal, Naina V, Narayan, Ashwini, Naveen Kumar, C. N, Nanduri, Robert, Bharath, Sowmya, Reddy, Jitendar, Panduga, Vijender, Prabhakar, K. R, Kandaswamy, Karthikeyan, Saralaya, Ramanatha, Kaur, Parvinder, Dinesh, Neela, Guptha, Supreeth, Rich, Kirsty, Murray, David, Plant, Helen, Preston, Marian, Ashton, Helen, Plant, Darren, Walsh, Jarrod, Alcock, Peter, Naylor, Kathryn, Collier, Matthew, Whiteaker, James, McLaughlin, Robert E, Mallya, Meenakshi, Panda, Manoranjan, Rudrapatna, Suresh, Ramachandran, Vasanthi, Shandil, Radha, Sambandamurthy, Vasan K, Mdluli, Khisi, Cooper, Christopher B, Rubin, Harvey, Yano, Takahiro, Iyer, Pravin, Narayanan, Shridhar, Kavanagh, Stefan, Mukherjee, Kakoli, Balasubramanian, V, Hosagrahara, Vinayak P, Solapure, Suresh, Ravishankar, Sudha, Hameed P, Shahul

“…The approval of bedaquiline to treat tuberculosis has validated adenosine triphosphate (ATP) synthase as an attractive target to kill Mycobacterium…”
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Whole cell screen based identification of spiropiperidines with potent antitubercular properties by Tantry, Subramanyam J., Degiacomi, Giulia, Sharma, Sreevalli, Jena, Lalit kumar, Narayan, Ashwini, Guptha, Supreeth, Shanbhag, Gajanan, Menasinakai, Sreenivasaiah, Mallya, Meenakshi, Awasthy, Disha, Balakrishnan, Gayathri, Kaur, Parvinder, Bhattacharjee, Deepa, Narayan, Chandan, Reddy, Jitendar, Naveen Kumar, C.N., Shandil, Radha, Boldrin, Francesca, Ventura, Marcello, Manganelli, Riccardo, Hartkoorn, Ruben C., Cole, Stewart T., Panda, Manoranjan, Markad, Shankar D., Ramachandran, Vasanthi, Ghorpade, Sandeep R., Dinesh, Neela

“…[Display omitted] Whole cell based screens to identify hits against Mycobacterium tuberculosis (Mtb), carried out under replicating and non-replicating (NRP)…”
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Thiazolopyridone ureas as DNA gyrase B inhibitors: Optimization of antitubercular activity and efficacy by Kale, Ramesh R., Kale, Manoj G., Waterson, David, Raichurkar, Anandkumar, Hameed, Shahul P., Manjunatha, M.R., Kishore Reddy, B.K., Malolanarasimhan, Krishnan, Shinde, Vikas, Koushik, Krishna, Jena, Lalit Kumar, Menasinakai, Sreenivasaiah, Humnabadkar, Vaishali, Madhavapeddi, Prashanti, Basavarajappa, Halesha, Sharma, Sreevalli, Nandishaiah, Radha, Mahesh Kumar, K.N., Ganguly, Samit, Ahuja, Vijaykamal, Gaonkar, Sheshagiri, Naveen Kumar, C.N., Ogg, Derek, Boriack-Sjodin, P. Ann, Sambandamurthy, Vasan K., de Sousa, Sunita M., Ghorpade, Sandeep R.

“…Scaffold hopping from the thiazolopyridine ureas led to thiazolopyridone ureas with potent antitubercular activity acting through inhibition of DNA GyrB ATPase…”
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Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B by Kale, Manoj G, Raichurkar, Anandkumar, P, Shahul Hameed, Waterson, David, McKinney, David, Manjunatha, M. R, Kranthi, Usha, Koushik, Krishna, Jena, Lalit kumar, Shinde, Vikas, Rudrapatna, Suresh, Barde, Shubhada, Humnabadkar, Vaishali, Madhavapeddi, Prashanti, Basavarajappa, Halesha, Ghosh, Anirban, Ramya, VK, Guptha, Supreeth, Sharma, Sreevalli, Vachaspati, Prakash, Kumar, K.N. Mahesh, Giridhar, Jayashree, Reddy, Jitendar, Panduga, Vijender, Ganguly, Samit, Ahuja, Vijaykamal, Gaonkar, Sheshagiri, Kumar, C. N. Naveen, Ogg, Derek, Tucker, Julie A, Boriack-Sjodin, P. Ann, de Sousa, Sunita M, Sambandamurthy, Vasan K, Ghorpade, Sandeep R

“…A pharmacophore-based search led to the identification of thiazolopyridine ureas as a novel scaffold with antitubercular activity acting through inhibition of…”
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Left-Hand Side Exploration of Novel Bacterial Topoisomerase Inhibitors to Improve Selectivity against hERG Binding by Hameed P, Shahul, Manjrekar, Praveena, Raichurkar, Anandkumar, Shinde, Vikas, Puttur, Jayashree, Shanbhag, Gajanan, Chinnapattu, Murugan, Patil, Vikas, Rudrapatana, Suresh, Sharma, Sreevalli, Kumar, C. N. Naveen, Nandishaiah, Radha, Madhavapeddi, Prashanti, Sriram, D, Solapure, Suresh, Sambandamurthy, Vasan K

“…Structure–activity relationship (SAR) exploration on the left-hand side (LHS) of a novel class of bacterial topoisomerase inhibitors led to a significant…”
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S68. DIFFERENTIAL PATTERN OF SOCIAL COGNITION IMPAIRMENT BETWEEN RURAL AND URBAN DWELLING PATIENTS OF SCHIZOPHRENIA AND ITS FUNCTIONAL CORRELATES by Ibrahim, Ferose, Mehta, Urvakhsh M, Keshav Kumar, J K, Nair, Sreekanth, Gowda, Swetha, Rakesh, K R, Naveen Kumar, C N, Thirthalli, Jagadisha

“…Abstract Background Cognitive deficits (both neuro & social Cognition) play a vital role in determining functional status in schizophrenia. It has been noted…”
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Novel N‑Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis by Hameed P, Shahul, Patil, Vikas, Solapure, Suresh, Sharma, Umender, Madhavapeddi, Prashanti, Raichurkar, Anandkumar, Chinnapattu, Murugan, Manjrekar, Praveena, Shanbhag, Gajanan, Puttur, Jayashree, Shinde, Vikas, Menasinakai, Sreenivasaiah, Rudrapatana, Suresh, Achar, Vijayashree, Awasthy, Disha, Nandishaiah, Radha, Humnabadkar, Vaishali, Ghosh, Anirban, Narayan, Chandan, Ramya, V. K, Kaur, Parvinder, Sharma, Sreevalli, Werngren, Jim, Hoffner, Sven, Panduga, Vijender, Kumar, C. N. Naveen, Reddy, Jitendar, Kumar KN, Mahesh, Ganguly, Samit, Bharath, Sowmya, Bheemarao, Ugarkar, Mukherjee, Kakoli, Arora, Uma, Gaonkar, Sheshagiri, Coulson, Michelle, Waterson, David, Sambandamurthy, Vasan K, de Sousa, Sunita M

“…DNA gyrase is a clinically validated target for developing drugs against Mycobacterium tuberculosis (Mtb). Despite the promise of fluoroquinolones (FQs) as…”
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