Search Results - "Navarro‐Partida, José"
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Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
Published in Journal of diabetes research (2019)“…Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous…”
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An insight on the eye bacterial microbiota and its role on dry eye disease
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-03-2023)“…The human ocular surface hosts a bacterial assemblage that integrates a diverse and complex microbiome. This bacterial microbiota is part of a healthy eye and…”
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Microbial Dynamics in Ophthalmic Health: Exploring the Interplay between Human Microbiota and Glaucoma Pathogenesis
Published in Medicina (Kaunas, Lithuania) (01-04-2024)“…The human microbiome has a crucial role in the homeostasis and health of the host. These microorganisms along with their genes are involved in various…”
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Mesenchymal Stem Cells: Case Report of an Adjuvant Ambulatory Therapy for a COVID-19 High-Risk and Steroid-hypersensitive Patients
Published in Current stem cell research & therapy (01-01-2023)“…Due to the rapid progression of COVID-19 to severe and critical stages, thousands of patients have required the use of intensive care unit (ICU) treatment,…”
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HPLC-UV evaluation of a microwave assisted method as an active drug loading technique for exosome-based drug delivery system
Published in Heliyon (01-10-2023)“…This paper evaluates the potential of a microwave radiation (MR) assisted method as an active drug loading technique for exosomes using polyphenolic…”
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Pirfenidone Accelerates Wound Healing in Chronic Diabetic Foot Ulcers: A Randomized, Double-Blind Controlled Trial
Published in Journal of diabetes research (01-01-2017)“…Background. Diabetic foot ulcers are one disabling complication of diabetes mellitus. Pirfenidone (PFD) is a potent modulator of extracellular matrix. Modified…”
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Relacion entre los polimorfismos funcionales de nucleotido unico del TGF-β1 y el glaucoma primario de angulo abierto en una poblacion mexicana
Published in Revista mexicana de oftalmología (23-12-2022)“…Objetivo: La asociación entre el factor de crecimiento transformante beta 1 (TGF-β1) y el glaucoma primario de ángulo abierto (GPAA) ha sido poco estudiada. El…”
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A new opportunity for N-acetylcysteine. An outline of its classic antioxidant effects and its pharmacological potential as an epigenetic modulator in liver diseases treatment
Published in Naunyn-Schmiedeberg's archives of pharmacology (22-10-2024)“…Liver diseases represent a worldwide health problem accountable for two million deaths per year. Oxidative stress is critical for the development of these…”
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Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK
Published in Hepatology communications (01-03-2020)“…Nonalcoholic steatohepatitis (NASH) is recognized by hepatic lipid accumulation, inflammation, and fibrosis. No studies have evaluated the prolonged‐release…”
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Educación en línea y enfermedad del ojo seco durante la pandemia de COVID-19
Published in Revista mexicana de oftalmología (01-12-2022)“…Objetivo: Analizar los cambios en la frecuencia y la incidencia de la enfermedad del ojo seco (EOS) y los tiempos de exposición a pantallas al inicio de cursos…”
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Polimorfismos funcionales del gen VEGF no están asociados con degeneración macular relacionada con la edad en población mexicana
Published in Revista mexicana de oftalmología (01-06-2020)Get full text
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Therapies Based on Nanoparticles for Eye Drug Delivery
Published in Ophthalmology and therapy (07-05-2020)“…Eye drug delivery, particularly to the retina, is a technical hurdle that needs to be solved and represents an ongoing current important medical field…”
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Polymeric Implants for the Treatment of Intraocular Eye Diseases: Trends in Biodegradable and Non-Biodegradable Materials
Published in Pharmaceutics (12-05-2021)“…Intraocular/Intravitreal implants constitute a relatively new method to treat eye diseases successfully due to the possibility of releasing drugs in a…”
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Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology
Published in Nutrients (25-11-2022)“…Oxidative stress represents one of the main factors driving the pathophysiology of multiple ophthalmic conditions including presbyopia, cataracts, dry eye…”
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Lipid-Based Nanocarriers as Topical Drug Delivery Systems for Intraocular Diseases
Published in Pharmaceutics (09-05-2021)“…Effective drug delivery to intraocular tissues remains a great challenge due to complex anatomical and physiological barriers that selectively limit the entry…”
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Enhancing Ocular Surface in Dry Eye Disease Patients: A Clinical Evaluation of a Topical Formulation Containing Sesquiterpene Lactone Helenalin
Published in Pharmaceuticals (Basel, Switzerland) (30-01-2024)“…The aim of this work was to assess the tolerability, safety, and efficacy of an ophthalmic topical formulation containing helenalin from and hyaluronic acid…”
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An Oral Polyphenol Formulation to Modulate the Ocular Surface Inflammatory Process and to Improve the Symptomatology Associated with Dry Eye Disease
Published in Nutrients (07-08-2022)“…Due to their antioxidant, anti-inflammatory, neuroprotective, and anti-angiogenic effects, polyphenols are first-rate candidates to prevent or treat chronic…”
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Safety and efficacy of topical interferon alpha 2B and mitomycin C for localized conjunctival intraepithelial neoplasia: long-term report of their pharmacological safety and efficacy
Published in BMC ophthalmology (27-07-2023)“…Ocular surface squamous neoplasia (OSSN) comprises a wide spectrum of squamous tumors, from which corneal/conjunctival intraepithelial neoplasia (CIN) is the…”
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The multifaceted role of pirfenidone and its novel targets
Published in Fibrogenesis & tissue repair (01-09-2010)“…Pirfenidone (PFD) is a molecule that exhibits antifibrotic properties in a variety of in vitro and animal models of lung, liver and renal fibrosis. These…”
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