Search Results - "Navarro, Miguel"

Assessment of computational methods for the analysis of single-cell ATAC-seq data by Chen, Huidong, Lareau, Caleb, Andreani, Tommaso, Vinyard, Michael E, Garcia, Sara P, Clement, Kendell, Andrade-Navarro, Miguel A, Buenrostro, Jason D, Pinello, Luca

“…Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of…”
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Prediction of protein secondary structure from circular dichroism using theoretically derived spectra by Louis-Jeune, Caroline, Andrade-Navarro, Miguel A., Perez-Iratxeta, Carol

“…Circular dichroism (CD) is a spectroscopic technique commonly used to investigate the structure of proteins. Major secondary structure types, alpha‐helices and…”
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HIPPIE v2.0: enhancing meaningfulness and reliability of protein-protein interaction networks by Alanis-Lobato, Gregorio, Andrade-Navarro, Miguel A, Schaefer, Martin H

“…The increasing number of experimentally detected interactions between proteins makes it difficult for researchers to extract the interactions relevant for…”
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Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases by Tørresen, Ole K, Star, Bastiaan, Mier, Pablo, Andrade-Navarro, Miguel A, Bateman, Alex, Jarnot, Patryk, Gruca, Aleksandra, Grynberg, Marcin, Kajava, Andrey V, Promponas, Vasilis J, Anisimova, Maria, Jakobsen, Kjetill S, Linke, Dirk

“…Abstract The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for…”
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Third-harmonic-upconversion enhancement from a single semiconductor nanoparticle coupled to a plasmonic antenna by Aouani, Heykel, Rahmani, Mohsen, Navarro-Cía, Miguel, Maier, Stefan A.

“…The ability to convert low-energy quanta into a quantum of higher energy is of great interest for a variety of applications, including bioimaging 1 , drug…”
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Detection of features predictive of microRNA targets by integration of network data by Cihan, Mert, Andrade-Navarro, Miguel A

“…Gene activity is controlled by multiple molecular mechanisms, for instance through transcription factors or by microRNAs (miRNAs), among others. Established…”
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HIPPIE: Integrating protein interaction networks with experiment based quality scores by Schaefer, Martin H, Fontaine, Jean-Fred, Vinayagam, Arunachalam, Porras, Pablo, Wanker, Erich E, Andrade-Navarro, Miguel A

“…Protein function is often modulated by protein-protein interactions (PPIs) and therefore defining the partners of a protein helps to understand its activity…”
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Evolutionary stability of topologically associating domains is associated with conserved gene regulation by Krefting, Jan, Andrade-Navarro, Miguel A, Ibn-Salem, Jonas

“…The human genome is highly organized in the three-dimensional nucleus. Chromosomes fold locally into topologically associating domains (TADs) defined by…”
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Modular Design for Versatile Broadband Polarizing Metasurfaces with Freely Switching Functions by Song, Kun, Gong, Xuejian, Cao, Yunshan, Chen, Qiang, Ji, Ruonan, Liu, Yahong, Zhao, Xiaopeng, Zhou, Jiangfeng, Navarro‐Cía, Miguel

“…Polarization is a fundamental property of electromagnetic waves that plays a key role in many physical phenomena and applications. Schemes to manipulate it are…”
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Recent progress in terahertz metamaterial modulators by Degl’Innocenti, Riccardo, Lin, Hungyen, Navarro-Cía, Miguel

“…The terahertz (0.1–10 THz) range represents a fast-evolving research and industrial field. The great interest for this portion of the electromagnetic spectrum,…”
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Batch effect detection and correction in RNA-seq data using machine-learning-based automated assessment of quality by Sprang, Maximilian, Andrade-Navarro, Miguel A, Fontaine, Jean-Fred

“…Abstract Background The constant evolving and development of next-generation sequencing techniques lead to high throughput data composed of datasets that…”
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Efficient embedding of complex networks to hyperbolic space via their Laplacian by Alanis-Lobato, Gregorio, Mier, Pablo, Andrade-Navarro, Miguel A.

“…The different factors involved in the growth process of complex networks imprint valuable information in their observable topologies. How to exploit this…”
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Prediction of protein secondary structure from circular dichroism using theoretically derived spectra by Louis-Jeune, Caroline, Andrade-Navarro, Miguel A., Perez-Iratxeta, Carol

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The Protein Structure Context of PolyQ Regions by Totzeck, Franziska, Andrade-Navarro, Miguel A, Mier, Pablo

“…Proteins containing glutamine repeats (polyQ) are known to be structurally unstable. Abnormal expansion of polyQ in some proteins exceeding a certain threshold…”
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Context characterization of amino acid homorepeats using evolution, position, and order by Mier, Pablo, Alanis‐Lobato, Gregorio, Andrade‐Navarro, Miguel A.

“…ABSTRACT Amino acid repeats, or homorepeats, are low complexity protein motifs consisting of tandem repetitions of a single amino acid. Their presence and…”
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Assessing the low complexity of protein sequences via the low complexity triangle by Mier, Pablo, Andrade-Navarro, Miguel A

“…Proteins with low complexity regions (LCRs) have atypical sequence and structural features. Their amino acid composition varies from the expected, determined…”
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Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC by Voss, Felizia K., Ullrich, Florian, Münch, Jonas, Lazarow, Katina, Lutter, Darius, Mah, Nancy, Andrade-Navarro, Miguel A., von Kries, Jens P., Stauber, Tobias, Jentsch, Thomas J.

“…Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion…”
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Chem-CRISPR/dCas9FCPF: a platform for chemically induced epigenome editing by Altinbay, Mukaddes, Wang, Jianhui, Chen, Jie, Schäfer, Daniel, Sprang, Maximilian, Blagojevic, Biljana, Wölfl, Stefan, Andrade-Navarro, Miguel A, Dikic, Ivan, Knapp, Stefan, Cheng, Xinlai

“…Epigenetic aberration is one of the major driving factors in human cancer, often leading to acquired resistance to chemotherapies. Various small molecule…”
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Between Interactions and Aggregates: The PolyQ Balance by Mier, Pablo, Andrade-Navarro, Miguel A

“…Polyglutamine (polyQ) regions are highly abundant consecutive runs of glutamine residues. They have been generally studied in relation to the so-called…”
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The transcriptional co‐activator Yap1 promotes adult hippocampal neural stem cell activation by Fan, Wenqiang, Jurado‐Arjona, Jerónimo, Alanis‐Lobato, Gregorio, Péron, Sophie, Berger, Christian, Andrade‐Navarro, Miguel A, Falk, Sven, Berninger, Benedikt

“…Most adult hippocampal neural stem cells (NSCs) remain quiescent, with only a minor portion undergoing active proliferation and neurogenesis. The molecular…”
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