Search Results - "Navarro, María A."
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Endoplasmic Reticulum Protein TXNDC5 Interacts with PRDX6 and HSPA9 to Regulate Glutathione Metabolism and Lipid Peroxidation in the Hepatic AML12 Cell Line
Published in International journal of molecular sciences (05-12-2023)“…Non-alcoholic fatty liver disease or steatosis is an accumulation of fat in the liver. Increased amounts of non-esterified fatty acids, calcium deficiency, or…”
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2
Thioredoxin Domain Containing 5 (TXNDC5): Friend or Foe?
Published in Current issues in molecular biology (01-04-2024)“…This review focuses on the thioredoxin domain containing 5 (TXNDC5), also known as endoplasmic reticulum protein 46 (ERp46), a member of the protein disulfide…”
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3
Dietary Erythrodiol Modifies Hepatic Transcriptome in Mice in a Sex and Dose-Dependent Way
Published in International journal of molecular sciences (01-10-2020)“…Erythrodiol is a terpenic compound found in a large number of plants. To test the hypotheses that its long-term administration may influence hepatic…”
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4
TXNDC5 Plays a Crucial Role in Regulating Endoplasmic Reticulum Activity through Different ER Stress Signaling Pathways in Hepatic Cells
Published in International journal of molecular sciences (28-06-2024)“…The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is influenced by a number of variables, including endoplasmic reticulum stress (ER). Thioredoxin…”
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Dietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice
Published in PloS one (12-08-2014)“…Squalene, the main hydrocarbon in the unsaponifiable fraction of virgin olive oil, is involved in cholesterol synthesis and it has been reported to own…”
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Thioredoxin domain containing 5 is involved in the hepatic storage of squalene into lipid droplets in a sex-specific way
Published in The Journal of nutritional biochemistry (01-02-2024)“…Hepatic thioredoxin domain-containing 5 (TXNDC5) is a member of the protein disulfide isomerase family found associated with anti-steatotic properties of…”
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The Search for Dietary Supplements to Elevate or Activate Circulating Paraoxonases
Published in International journal of molecular sciences (15-02-2017)“…Low levels of paraoxonase 1 (PON1) have been associated with the development of several pathological conditions, whereas high levels have been shown to be…”
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Transcriptomics and the Mediterranean Diet: A Systematic Review
Published in Nutrients (09-05-2017)“…The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases and cancer and in decreasing overall mortality…”
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Dietary proteins modulate high-density lipoprotein characteristics in a sex-specific way in Apoe-deficient mice
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-12-2023)“…•Bird protein consumption reduces arteriosclerosis lesions in Apoe knockout mice.•The smallest lesion was associated with a higher ratio of PON1 to…”
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Pgc1a is responsible for the sex differences in hepatic Cidec/Fsp27β mRNA expression in hepatic steatosis of mice fed a Western diet
Published in American journal of physiology: endocrinology and metabolism (01-02-2020)“…Hepatic fat-specific protein 27 [cell death-inducing DNA fragmentation effector protein C ( )/ ] mRNA levels have been associated with hepatic lipid droplet…”
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PON1 and Mediterranean Diet
Published in Nutrients (27-05-2015)“…The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases. Paraoxonase 1 (PON1) has been implicated in the…”
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Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II–induced hypertrophy
Published in The FASEB journal (01-09-2017)“…ABSTRACT Lysyl oxidase (LOX) controls matrix remodeling, a key process that underlies cardiovascular diseases and heart failure; however, a lack of suitable…”
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13
Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil
Published in PloS one (29-01-2013)“…The present study was designed to verify the influence of acute fat loading on high density lipoprotein (HDL) composition, and the involvement of liver and…”
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Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-12-2020)“…Background and aims. The molecular mechanisms by which the liver develops steatotic disease still remain unclear. Previous studies using nutritional and…”
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15
Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury
Published in Human molecular genetics (15-05-2013)“…We have previously shown that NOR-1 (NR4A3) modulates the proliferation and survival of vascular cells in culture. However, in genetically modified animal…”
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Dietary Avian Proteins Are Comparable to Soybean Proteins on the Atherosclerosis Development and Fatty Liver Disease in Apoe-Deficient Mice
Published in Nutrients (27-05-2021)“…Background and aim: The type and amount of dietary protein has become a topic of renewed interest in light of their involvement in metabolic diseases,…”
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Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver
Published in Physiological genomics (01-05-2009)“…1 Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto Aragonés de Ciencias de la Salud (Universidad de Zaragoza-Salud…”
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Thioredoxin Domain Containing 5 Suppression Elicits Serum Amyloid A-Containing High-Density Lipoproteins
Published in Biomedicines (18-03-2022)“…Thioredoxin domain containing 5 (TXNDC5) is a protein disulfide isomerase involved in several diseases related to oxidative stress, energy metabolism and…”
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Selection of reference genes for gene expression studies in rats
Published in Journal of biotechnology (20-02-2011)“…Selection of the most stable reference gene is critical for a reliable interpretation of gene expression data using RT-PCR. In order so, 17 commonly used genes…”
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Pulsed electric field increases the extraction yield of extra virgin olive oil without loss of its biological properties
Published in Frontiers in nutrition (Lausanne) (22-11-2022)“…Pulsed electric field (PEF) has been used for improving extraction of extra virgin olive oil (EVOO). However, the biological changes induced by the consumption…”
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