Search Results - "Navarro, José Fernandéz"

Single-cell and spatial transcriptomics enables probabilistic inference of cell type topography by Andersson, Alma, Bergenstråhle, Joseph, Asp, Michaela, Bergenstråhle, Ludvig, Jurek, Aleksandra, Fernández Navarro, José, Lundeberg, Joakim

“…The field of spatial transcriptomics is rapidly expanding, and with it the repertoire of available technologies. However, several of the transcriptome-wide…”
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Enhancing Maize Stress Tolerance and Productivity through Synergistic Application of Bacillus velezensis A6 and Lamiales Plant Extract, Biostimulants Suitable for Organic Farming by Peñas-Corte, María, Bouzas, Paula R, Nieto Del Río, Juan, Manzanera, Maximino, Barros-Rodríguez, Adoración, Fernández-Navarro, José R

“…Maize, a globally significant cereal, is increasingly cultivated under challenging environmental conditions, necessitating innovations in sustainable…”
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Ultrasonographic study of the orbit as an early diagnostic tool in Vogt Koyanagi Harada disease (VKH): A case report by Fernández-Navarro, José, García-García, Jorge, Gregorio García-García, José, Segura, Tomás

“…In recent years, ultrasound has demonstrated its usefulness in the approach to vascular structures and other tissues such as the orbit, facilitating the early…”
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Characterization of a Novel Thermostable Carboxylesterase from Geobacillus kaustophilus HTA426 Shows the Existence of a New Carboxylesterase Family by Montoro-García, Silvia, Martínez-Martínez, Irene, Navarro-Fernández, José, Takami, Hideto, García-Carmona, Francisco, Sánchez-Ferrer, Alvaro

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Amelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism by Martínez-Martínez, Irene, Navarro-Fernández, José, Østergaard, Alice, Gutiérrez-Gallego, Ricardo, Padilla, José, Bohdan, Nataliya, Miñano, Antonia, Pascual, Cristina, Martínez, Constantino, de la Morena-Barrio, María Eugenia, Águila, Sonia, Pedersen, Shona, Kristensen, Søren Risom, Vicente, Vicente, Corral, Javier

“…The balance between actions of procoagulant and anticoagulant factors protects organisms from bleeding and thrombosis. Thus, antithrombin deficiency increases…”
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Improved cross-linked enzyme aggregates for the production of desacetyl β-lactam antibiotics intermediates by Montoro-García, Silvia, Gil-Ortiz, Fernando, Navarro-Fernández, José, Rubio, Vicente, García-Carmona, Francisco, Sánchez-Ferrer, Álvaro

“…Cross-linked enzyme aggregates (CLEAs) are reported for the first time for a recombinant acetyl xylan esterase (AXE) from Bacillus pumilus. With this enzyme,…”
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Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombin by Aguila, Sonia, Martínez-Martínez, Irene, Dichiara, Gilda, Gutiérrez-Gallego, Ricardo, Navarro-Fernández, José, Vicente, Vicente, Corral, Javier

“…The inefficient glycosylation of consensus sequence on N135 in antithrombin explains the two glycoforms of this key anticoagulant serpin found in plasma: α and…”
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High-definition spatial transcriptomics for in situ tissue profiling by Vickovic, Sanja, Eraslan, Gökcen, Salmén, Fredrik, Klughammer, Johanna, Stenbeck, Linnea, Schapiro, Denis, Äijö, Tarmo, Bonneau, Richard, Bergenstråhle, Ludvig, Navarro, José Fernandéz, Gould, Joshua, Griffin, Gabriel K., Borg, Åke, Ronaghi, Mostafa, Frisén, Jonas, Lundeberg, Joakim, Regev, Aviv, Ståhl, Patrik L.

“…Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking. Here, we developed…”
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Antithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation by Irene Martínez-Martínez, Adriana Ordóñez, José Navarro-Fernández, Ángel Pérez-Lara, Ricardo Gutiérrez-Gallego, Rafael Giraldo, Constantino Martínez, Esther Llop, Vicente Vicente, Javier Corral

“…Identification of mutations in the SERPINC1 gene has revealed different mechanisms responsible for antithrombin deficiency. Deletions and nonsense mutations…”
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Characterization of a New Rhamnogalacturonan Acetyl Esterase from Bacillus halodurans C-125 with a New Putative Carbohydrate Binding Domain by José Navarro-Fernández, Irene Martínez-Martínez, Silvia Montoro-García, Francisco García-Carmona, Hideto Takami, Álvaro Sánchez-Ferrer

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Visualization and analysis of gene expression in tissue sections by spatial transcriptomics by Ståhl, Patrik L., Salmén, Fredrik, Vickovic, Sanja, Lundmark, Anna, Navarro, José Fernández, Magnusson, Jens, Giacomello, Stefania, Asp, Michaela, Westholm, Jakub O., Huss, Mikael, Mollbrink, Annelie, Linnarsson, Sten, Codeluppi, Simone, Borg, Åke, Pontén, Fredrik, Costea, Paul Igor, Sahlén, Pelin, Mulder, Jan, Bergmann, Olaf, Lundeberg, Joakim, Frisén, Jonas

“…Analysis of the pattern of proteins or messenger RNAs (mRNAs) in histological tissue sections is a cornerstone in biomedical research and diagnostics. This…”
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Cervical Intramedullary Schwannoma: Case Report and Review of the Literature by Navarro Fernández, José Omar, Monroy Sosa, Alejandro, Cacho Díaz, Bernardo, Arrieta, Víctor Andrés, Ortíz Leyva, Ramses Uriel, Cano Valdez, Ana María, Reyes Soto, Gervith

“…Cervical intramedullary schwannomas are extraordinarily rare. Gross total resection is the best therapeutic option for these types of tumors. Although rare,…”
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Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease by Chen, Wei-Ting, Lu, Ashley, Craessaerts, Katleen, Pavie, Benjamin, Sala Frigerio, Carlo, Corthout, Nikky, Qian, Xiaoyan, Laláková, Jana, Kühnemund, Malte, Voytyuk, Iryna, Wolfs, Leen, Mancuso, Renzo, Salta, Evgenia, Balusu, Sriram, Snellinx, An, Munck, Sebastian, Jurek, Aleksandra, Fernandez Navarro, Jose, Saido, Takaomi C., Huitinga, Inge, Lundeberg, Joakim, Fiers, Mark, De Strooper, Bart

“…Although complex inflammatory-like alterations are observed around the amyloid plaques of Alzheimer’s disease (AD), little is known about the molecular changes…”
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Barcoded solid-phase RNA capture for Spatial Transcriptomics profiling in mammalian tissue sections by Salmén, Fredrik, Ståhl, Patrik L., Mollbrink, Annelie, Navarro, José Fernández, Vickovic, Sanja, Frisén, Jonas, Lundeberg, Joakim

“…Spatial resolution of gene expression enables gene expression events to be pinpointed to a specific location in biological tissue. Spatially resolved gene…”
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Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins? by de la Morena-Barrio, María Eugenia, Buil, Alfonso, Antón, Ana Isabel, Martínez-Martínez, Irene, Miñano, Antonia, Gutiérrez-Gallego, Ricardo, Navarro-Fernández, José, Aguila, Sonia, Souto, Juan Carlos, Vicente, Vicente, Soria, José Manuel, Corral, Javier

“…The haemostatic relevance of antithrombin together with the low genetic variability of SERPINC1, and the high heritability of plasma levels encourage the…”
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The infective polymerization of conformationally unstable antithrombin mutants may play a role in the clinical severity of antithrombin deficiency by Martínez-Martínez, Irene, Navarro-Fernández, José, Aguila, Sonia, Miñano, Antonia, Bohdan, Nataliya, De La Morena-Barrio, María Eugenia, Ordóñez, Adriana, Martínez, Constantino, Vicente, Vicente, Corral, Javier

“…Mutations affecting mobile domains of antithrombin induce conformational instability resulting in protein polymerization that associates with a severe clinical…”
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YesT: A new rhamnogalacturonan acetyl esterase from Bacillus subtilis by Martínez-Martínez, Irene, Navarro-Fernández, José, Daniel Lozada-Ramírez, José, García-Carmona, Francisco, Sánchez-Ferrer, Álvaro

“…YesT, a putative protein from Bacillus subtilis ATCC 6633 that has been provisionally classified as a rhamnogalacturonan acetyl esterase (RGAE) in CE‐12…”
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Identification and transfer of spatial transcriptomics signatures for cancer diagnosis by Yoosuf, Niyaz, Navarro, José Fernández, Salmén, Fredrik, Ståhl, Patrik L, Daub, Carsten O

“…Distinguishing ductal carcinoma in situ (DCIS) from invasive ductal carcinoma (IDC) regions in clinical biopsies constitutes a diagnostic challenge. Spatial…”
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ST viewer: a tool for analysis and visualization of spatial transcriptomics datasets by Fernández Navarro, José, Lundeberg, Joakim, Ståhl, Patrik L

“…Abstract Motivation Spatial Transcriptomics (ST) is a technique that combines high-resolution imaging with spatially resolved transcriptome-wide sequencing…”
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A novel platelet-activating factor acetylhydrolase discovered in a metagenome from the earthworm-associated microbial community by Navarro-Fernández, José, Nechitaylo, Taras Y., Guerrero, José A., Golyshina, Olga V., García-Carmona, Francisco, Sánchez-Ferrer, Álvaro, Golyshin, Peter N.

“…Summary Metagenomics is an emerging field for mining the bioresources for new biomolecules for potential application in biotechnology and biomedicine. In the…”
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