Search Results - "Navarro, Irene Rodriguez"

The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice by Espina, Marc, Di Franco, Nadia, Brañas-Navarro, Martina, Navarro, Irene Rodriguez, Brito, Veronica, Lopez-Molina, Laura, Costas-Insua, Carlos, Guzmán, Manuel, Ginés, Silvia

“…Increasing evidence indicates that a key factor in neurodegenerative diseases is the activation of the unfolded protein response (UPR) caused by an…”
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TLR4 Deficiency Affects the Microbiome and Reduces Intestinal Dysfunctions and Inflammation in Chronic Alcohol-Fed Mice by Cuesta, Carlos M, Pascual, María, Pérez-Moraga, Raúl, Rodríguez-Navarro, Irene, García-García, Francisco, Ureña-Peralta, Juan R, Guerri, Consuelo

“…Chronic alcohol abuse causes an inflammatory response in the intestinal tract with damage to the integrity of the mucosa and epithelium, as well as dysbiosis…”
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m6A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts by Pupak, Anika, Rodríguez-Navarro, Irene, Sathasivam, Kirupa, Singh, Ankita, Essmann, Amelie, del Toro, Daniel, Ginés, Silvia, Mouro Pinto, Ricardo, Bates, Gillian P, Vang Ørom, Ulf Andersson, Martí, Eulàlia, Brito, Verónica

“…In Huntington’s disease (HD), aberrant processing of huntingtin ( HTT ) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
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Postnatal Foxp2 regulates early psychiatric-like phenotypes and associated molecular alterations in the R6/1 transgenic mouse model of Huntington's disease by Rodríguez-Urgellés, Ened, Rodríguez-Navarro, Irene, Ballasch, Iván, del Toro, Daniel, del Castillo, Ignacio, Brito, Verónica, Alberch, Jordi, Giralt, Albert

“…Huntington's Disease (HD) is a devastating disorder characterized by a triad of motor, psychiatric and cognitive manifestations. Psychiatric and emotional…”
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A04 Role of RNA M6A modification in post-transcriptional regulation of mutant huntingtin expression by Pupak, Anika, Rodriguez-Navarro, Irene, Singh, Ankita, Ørom, Ulf Vang, Alberch, Jordi, Ginés, Silvia, Brito, Verónica

“…BackgroundThe ‘exon 1 fragment’ of mutant HTT has been postulated as a key driver of neurotoxicity in Huntington´s Disease. It can be generated by proteolytic…”
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m 6 A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts by Pupak, Anika, Rodríguez-Navarro, Irene, Sathasivam, Kirupa, Singh, Ankita, Essmann, Amelie, Del Toro, Daniel, Ginés, Silvia, Mouro Pinto, Ricardo, Bates, Gillian P, Vang Ørom, Ulf Andersson, Martí, Eulàlia, Brito, Verónica

“…In Huntington's disease (HD), aberrant processing of huntingtin (HTT) mRNA produces HTT1a transcripts that encode the pathogenic HTT exon 1 protein. The…”
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