Search Results - "Navarra, P."
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Expression of iNOS, CD163 and ARG-1 taken as M1 and M2 markers of microglial polarization in human glioblastoma and the surrounding normal parenchyma
Published in Neuroscience letters (03-04-2017)“…•iNOS, CD163 and ARG-I were investigated in GBM tumors and in the surrounding parenchyma from the same patients.•CD163 expression was higher within GBM…”
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Compassionate drug uses and saving for the national health system: the case study of Fondazione Policlinico Gemelli
Published in European review for medical and pharmacological sciences (01-10-2021)“…Compassionate Drug Use (CDU) allows patients with a specific disease and no further treatment option to access unauthorized treatments. In this study, we…”
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Effects of remifentanil on human C20 microglial pro-inflammatory activation
Published in European review for medical and pharmacological sciences (01-08-2021)“…Remifentanil (RF) is a potent short-acting μ-opioid receptor agonist. Although preferred for its unique pharmacokinetics, the clinical use may be limited by…”
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Lacosamide inhibits calcitonin gene-related peptide production and release at trigeminal level in the rat
Published in European journal of pain (01-07-2016)“…Background Several classes of drugs are effective in prevention and treatment of migraine, although they may differ among each other in their mode of action…”
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Rapamycin reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis
Published in Journal of neuroimmunology (29-02-2012)“…Abstract Current treatments used in Multiple Sclerosis (MS) are partly effective in the early stages of the disease but display very limited benefits in…”
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The safety profile of probiotic VSL#3®. A meta-analysis of safety data from double-blind, randomized, placebo-controlled clinical trials
Published in European review for medical and pharmacological sciences (01-01-2020)“…A high-concentration of a multi-strain probiotic mixture, VSL#3® is widely used 'whenever it is useful to promote the balance of intestinal flora'. As a food…”
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Relationship between blood remifentanil concentration and stress hormone levels during pneumoperitoneum in patients undergoing laparoscopic cholecystectomy
Published in European review for medical and pharmacological sciences (01-10-2017)“…The effect of remifentanil on stress response to surgery is unclear. However, there are not clinical studies investigating the relationship between blood…”
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Stress‐related biomarkers of dream recall and implicit memory under anaesthesia
Published in Anaesthesia (01-11-2013)“…Summary The aim of this study was to investigate whether auditory presentation of a story during general anaesthesia might influence stress hormone changes and…”
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Ore storage simulation for planning a concentrator expansion
Published in Minerals engineering (01-01-2013)“…[Display omitted] ► Integration of three simulators in a mine-to-mill application. ► Plant expansion feasibility linked to an ore storage bottleneck. ►…”
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Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus
Published in European journal of pain (01-09-2012)“…Background Gamma‐aminobutyric acid (GABA) and glutamate (GLU) are involved in nociceptive signals processing in the trigeminal system. In this study, we…”
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AMPA- and P2X7-receptor-mediated facilitation of [ 3H] d-aspartate release from nerve terminals isolated from the rat caudal brainstem
Published in Neurochemistry international (01-11-2010)“…Glutamate (GLU) plays a key role in the transmission and modulation of sensory input to the trigeminal caudal nuclei (TCN). In the present study, we…”
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Mid‐dosing interval concentration of atazanavir and virological outcome in patients treated for HIV‐1 infection
Published in HIV medicine (01-05-2010)“…Objectives We investigated the clinical significance of monitoring the mid‐dosing interval atazanavir (ATV) concentration (measured 12 ± 2 h after intake; C12…”
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Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin
Published in Hormone and metabolic research (01-08-2003)“…Ghrelin and synthetic growth hormone secretagogues have diverse effects on the hypothalamus including effects on appetite and the growth hormone axis as well…”
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Relationship between antiretroviral plasma concentration and emergence of HIV-1 resistance mutations at treatment failure
Published in Infection (01-12-2011)“…Purpose The relationship between antiretroviral pharmacokinetic exposure and acquisition of human immunodeficency virus-1 (HIV-1) drug resistance mutations…”
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Effects of the administration of epidermal growth factor receptor specific inhibitor cetuximab, alone and in combination with cisplatin, on proliferation and apoptosis of Hep-2 laryngeal cancer cells
Published in Journal of laryngology and otology (01-10-2014)“…Epidermal growth factor receptor (EGFR) overexpression and prognostic value in head and neck squamous cell cancer is the basis for targeting by anti-EGFR…”
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Linezolid use in ventilator-associated pneumonia: look at the body weight of your patient
Published in Minerva anestesiologica (01-12-2012)Get full text
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Pharmacokinetics of etravirine in HIV-infected patients concomitantly treated with rifampin for tuberculosis
Published in Infection (01-08-2014)“…Etravirine is metabolized by three cytochrome P450 enzymes that are in turn induced by rifampin. Consequently, co-administration of etravirine and rifampin is…”
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Protective properties of idebenone in noise-induced hearing loss in the guinea pig
Published in Neuroreport (26-06-2006)“…Idebenone is a synthetic analogue of coenzyme Q10 with antioxidant properties. The present study investigated the antioxidant activity of idebenone in the…”
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Nociceptin (1-13)NH2 inhibits stimulated calcitonin-gene-related-peptide release from primary cultures of rat trigeminal ganglia neurones
Published in Cephalalgia (01-08-2007)“…In this work we have developed and characterized primary cultures of neonatal rat trigeminal ganglia neurones; calcitonin-gene-related-peptide (CGRP) released…”
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Evidence That Hydrogen Sulphide Can Modulate Hypothalamo-Pituitary-Adrenal Axis Function: In Vitro and In Vivo Studies in the Rat
Published in Journal of neuroendocrinology (01-03-2000)“…The gas hydrogen sulphide (H2S) is normally produced in large amounts in the central nervous system during the metabolism of sulphur‐containing aminoacids. H2S…”
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