Search Results - "Nauta, Lauren E."

Up-regulation of MET but not neural cell adhesion molecule expression by the PAX3-FKHR fusion protein in alveolar rhabdomyosarcoma by GINSBERG, J. P, DAVIS, R. J, BENNICELLI, J. L, NAUTA, L. E, BARR, F. G

“…The 2;13 chromosomal translocation in alveolar rhabdomyosarcoma generates the chimeric protein PAX3-FKHR, which is a powerful transcriptional activator. We…”
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Molecular Assays for Chromosomal Translocations in the Diagnosis of Pediatric Soft Tissue Sarcomas by Barr, Frederic G, Chatten, Jane, D'Cruz, Celina M, Wilson, Albert E, Nauta, Lauren E, Nycum, Lynn M, Biegel, Jaclyn A, Womer, Richard B

“…Objective.—To compare molecular assays for characteristic chromosomal translocations with standard histopathologic and cytogenetic analysis in the differential…”
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Regulated Expression of the Diphtheria Toxin A Chain by a Tumor-Specific Chimeric Transcription Factor Results in Selective Toxicity for Alveolar Rhabdomyosarcoma Cells by Massuda, E S, Dunphy, E J, Redman, R A, Schreiber, J J, Nauta, L E, Barr, F G, Maxwell, I H, Cripe, T P

“…Alveolar rhabdomyosarcoma (ARMS) cells often harbor one of two unique chromosomal translocations, either t(2;13) (q35;q14) or t(1;13) (p36;q14). The chimeric…”
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In Vivo Amplification of the PAX3-FKHR and PAX7-FKHR Fusion Genes in Alveolar Rhabdomyosarcoma by Barr, Frederic G., Nauta, Lauren E., Davis, Richard J., Schafer, Beat W., Nycum, Lynn M., Biegel, Jaclyn A.

“…In the pediatric cancer alveolar rhabdomyosarcoma, characteristic t(2;13)(q35;q14) or variant t(1,13)(p36;q14) chromosomal translocations generate PAX3-FKHR or…”
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Structural Analysis of PAX3 Genomic Rearrangements in Alveolar Rhabdomyosarcoma by Barr, Frederic G., Nauta, Lauren E., Hollows, Julie C.

“…In the pediatric cancer alveolar rhabdomyosarcoma, the (2;13)(q35;q14) translocation juxtaposes PAX3 and FKHR to produce a chimeric PAX3-FKHR gene. With the…”
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