Search Results - "Naunyn-Schmiedeberg's archives of pharmacology"

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration by Gawel, Kinga, Gibula, Ewa, Marszalek-Grabska, Marta, Filarowska, Joanna, Kotlinska, Jolanta H.

“…Among the methods valuable for assessing spatial learning and memory impairments in rodents, the Barnes maze (BM) task deserves special attention. It is based…”
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Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion by Tang, Li-Jing, Luo, Xiu-Ju, Tu, Hua, Chen, Heng, Xiong, Xiao-Ming, Li, Nian-Sheng, Peng, Jun

“…Ferroptosis is an iron-dependent regulated necrosis. This study aims to evaluate the contribution of ferroptosis to ischemia or reperfusion injury, and lay a…”
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Vitamin D can prevent COVID-19 infection-induced multiple organ damage by Aygun, Hatice

“…Vitamin D is an immunomodulator hormone with an anti-inflammatory and antimicrobial effect with a high safety profile. A lot of COVID-19 infected patients…”
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Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases by Piechota-Polanczyk, Aleksandra, Fichna, Jakub

“…In this review, we focus on the role of oxidative stress in the aetiology of inflammatory bowel diseases (IBD) and colitis-associated colorectal cancer and…”
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Pleiotropic effects of statins: new therapeutic targets in drug design by Bedi, Onkar, Dhawan, Veena, Sharma, P. L., Kumar, Puneet

“…The HMG Co-enzyme inhibitors and new lipid-modifying agents expand their new therapeutic target options in the field of medical profession. Statins have been…”
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cGMP: a unique 2nd messenger molecule – recent developments in cGMP research and development by Friebe, Andreas, Sandner, Peter, Schmidtko, Achim

“…Cyclic guanosine monophosphate (cGMP) is a unique second messenger molecule formed in different cell types and tissues. cGMP targets a variety of downstream…”
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Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis by Temel, Yusuf, Kucukler, Sefa, Yıldırım, Serkan, Caglayan, Cuneyt, Kandemir, Fatih Mehmet

“…Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune disorders and malignant diseases. However, its usage is restricted due…”
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Rosemary (Rosmarinus officinalis) as a potential therapeutic plant in metabolic syndrome: a review by Hassani, Faezeh Vahdati, Shirani, Kobra, Hosseinzadeh, Hossein

“…Metabolic syndrome is defined by a constellation of complex coexisting cardiometabolic risk factors such as hyperglycemia, dyslipidemia, inflammation,…”
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A review of the bioactive components and pharmacological properties of Lavandula species by Batiha, Gaber El-Saber, Teibo, John Oluwafemi, Wasef, Lamiaa, Shaheen, Hazem M., Akomolafe, Ayomide Peter, Teibo, Titilade Kehinde Ayandeyi, Al-kuraishy, Hayder M., Al-Garbeeb, Ali I., Alexiou, Athanasios, Papadakis, Marios

“…Lavandula species is a flowering plant that is common in Europe and across the Mediterranean. Lavender has many health benefits for humans. In addition to its…”
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Unwinding circular RNA’s role in inflammatory pulmonary diseases by Bhat, Asif Ahmad, Gupta, Gaurav, Goyal, Ahsas, Thapa, Riya, Almalki, Waleed Hassan, Kazmi, Imran, Alzarea, Sami I., Kukreti, Neelima, Sekar, Mahendran, Meenakshi, Dhanalekshmi Unnikrishnan, Singh, Sachin Kumar, MacLoughlin, Ronan, Dua, Kamal

“…Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and cellular processes in various physiological and pathological conditions. In…”
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Effects of rosmarinic acid on nervous system disorders: an updated review by Ghasemzadeh Rahbardar, Mahboobeh, Hosseinzadeh, Hossein

“…Nowadays, the worldwide interest is growing to use medicinal plants and their active constituents to develop new potent medicines with fewer side effects…”
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Covid-19 and development of heart failure: mystery and truth by Onohuean, Hope, Al-kuraishy, Hayder M., Al-Gareeb, Ali I., Qusti, Safaa, Alshammari, Eida M., Batiha, Gaber El-Saber

“…Coronavirus disease 2019 (Covid-19) is a novel worldwide pandemic caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). During…”
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Ivermectin, antiviral properties and COVID-19: a possible new mechanism of action by Rizzo, Emanuele

“…Ivermectin is an antiparasitic drug that has shown also an effective pharmacological activity towards various infective agents, including viruses. This paper…”
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Nanomedicine and drug delivery to the retina: current status and implications for gene therapy by Tawfik, Mohamed, Chen, Fang, Goldberg, Jeffrey L., Sabel, Bernhard A.

“…Blindness affects more than 60 million people worldwide. Retinal disorders, including age-related macular degeneration (AMD), diabetic retinopathy (DR), and…”
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Canagliflozin mitigates ferroptosis and ameliorates heart failure in rats with preserved ejection fraction by Ma, Sai, He, Li-Li, Zhang, Guo-Rui, Zuo, Qing-Juan, Wang, Zhong-Li, Zhai, Jian-Long, Zhang, Ting-Ting, Wang, Yan, Ma, Hui-Juan, Guo, Yi-Fang

“…Recently, hypoglycemic drugs belonging to sodium-glucose cotransporter 2 inhibitors (SGLT2i) have generated significant interest due to their clear…”
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Emerging nanomaterials for antibacterial textile fabrication by Andra, Swetha, Balu, Satheesh kumar, Jeevanandam, Jaison, Muthalagu, Murugesan

“…In recent times, the search for innovative material to fabricate smart textiles has been increasing to satisfy the expectation and needs of the consumers, as…”
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Baicalin ameliorates lipopolysaccharide-induced acute lung injury in mice by suppressing oxidative stress and inflammation via the activation of the Nrf2-mediated HO-1 signaling pathway by Meng, Xiangli, Hu, Lin, Li, Wenqiang

“…This research aims to investigate the ameliorative potential of baicalin on lipopolysaccharide-induced acute lung injury by the suppression of oxidative stress…”
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Phytosynthesized metal oxide nanoparticles for pharmaceutical applications by Andra, Swetha, Balu, Satheesh Kumar, Jeevanandham, Jaison, Muthalagu, Murugesan, Vidyavathy, Manisha, Chan, Yen San, Danquah, Michael Kobina

“…Developments in nanotechnology field, specifically, metal oxide nanoparticles have attracted the attention of researchers due to their unique sensing,…”
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Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats by Nouri, Ali, Heibati, Fatemeh, Heidarian, Esfandiar

“…Paraquat (PRQ) is a toxic chemical compound that is very noxious to animals and humans. Gallic acid is a phenolic compound that has antioxidant properties. In…”
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Sensitization of MDA-MBA231 breast cancer cell to docetaxel by myricetin loaded into biocompatible lipid nanoparticles via sub-G1 cell cycle arrest mechanism by Maroufi, Nazila Fathi, Vahedian, Vahid, Mazrakhondi, Seyed Ali Miresmaeili, Kooti, Wesam, Khiavy, Hosein Ajami, Bazzaz, Roya, Ramezani, Fatemeh, Pirouzpanah, Seyed Mohammadbagher, Ghorbani, Marjan, Akbarzadeh, Maryam, Hajipour, Hamed, Ghanbarzadeh, Saeed, Sabzichi, Mehdi

“…The harmful dose-dependent side effects of chemotherapy drugs have caused the discovery of novel perspective to evaluate chemotherapy protocols. In this study,…”
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