Search Results - "Naumann, R."
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Advances in immunotherapy for cervical cancer
Published in Current opinion in oncology (01-09-2020)“…PURPOSE OF REVIEWNovel therapies are needed for the treatment of recurrent cervical cancer. The best chemotherapy regimen to date has a response rate of 48%…”
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Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial
Published in Journal of clinical oncology (01-11-2019)“…Nivolumab was assessed in patients with virus-associated tumors in the phase I/II CheckMate 358 trial (ClinicalTrials.gov identifier: NCT02488759). We report…”
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The SHAPE trial: is good is good enough?
Published in Journal of gynecologic oncology (01-07-2024)“…KCI Citation Count: 0…”
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Re-evaluating “Success” as It Pertains to Surgical Trials
Published in Journal of minimally invasive gynecology (01-03-2021)“…The objective of this article is to review the difficulties with the design and interpretation of surgical clinical trials. Few surgical procedures are…”
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The role of lymphadenectomy in endometrial cancer: Was the ASTEC trial doomed by design and are we destined to repeat that mistake?
Published in Gynecologic oncology (01-07-2012)“…Abstract Objective This study examines the design of previous and future trials of lymph node dissection in endometrial cancer. Methods Data from previous…”
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The impact of opportunistic salpingectomy on ovarian cancer mortality and healthcare costs: a call for universal insurance coverage
Published in American journal of obstetrics and gynecology (01-10-2021)“…Opportunistic salpingectomy at the time of hysterectomy or as an alternative to bilateral tubal ligation may reduce the incidence of ovarian cancer, because it…”
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Management Strategies for Recurrent Platinum-Resistant Ovarian Cancer
Published in Drugs (New York, N.Y.) (01-01-2011)“…Although ovarian cancer is often a chemosensitive malignancy, patients who are resistant to platinum-based chemotherapy represent a therapeutic challenge…”
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Role of Minimally Invasive Surgery in Gynecologic Oncology: An Updated Survey of Members of the Society of Gynecologic Oncology
Published in International journal of gynecological cancer (01-07-2015)“…To evaluate the current patterns of use of minimally invasive surgical procedures, including traditional, robotic-assisted, and single-port laparoscopy, by…”
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Ovarian cancer screening with the Risk of Ovarian Cancer Algorithm (ROCA): Good, bad, or just expensive?
Published in Gynecologic oncology (01-04-2018)“…To measure the effectiveness of ovarian cancer screening using the Risk of Ovarian Cancer Algorithm (ROCA). A Markov model was constructed based on the UK…”
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High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study)
Published in Leukemia (01-04-2017)“…To investigate immuno-chemotherapy for elderly immuno-competent patients (⩾65 years) with newly diagnosed primary central nervous system lymphoma, we conducted…”
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Phase III trials in ovarian cancer: The evolving landscape of front line therapy
Published in Gynecologic oncology (01-05-2019)“…Ovarian cancer has a high mortality to case ratio. To improve the initial response to therapy, trials of biologic agents in combination with primary…”
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Nivolumab with or without ipilimumab in patients with recurrent or metastatic cervical cancer (CheckMate 358): a phase 1–2, open-label, multicohort trial
Published in The lancet oncology (01-05-2024)“…In preliminary findings from the recurrent or metastatic cervical cancer cohort of CheckMate 358, nivolumab showed durable anti-tumour responses, and the…”
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The Benefits of Laparoscopic Radical Hysterectomy for Cervical Cancer: Res Ipsa Loquitur?
Published in Journal of minimally invasive gynecology (01-07-2022)“…Many studies have documented the peri-operative benefits of laparoscopic surgery. Despite the objective benefits to laparoscopic surgery, quality of life…”
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PRECEDENT: A Randomized Phase II Trial Comparing Vintafolide (EC145) and Pegylated Liposomal Doxorubicin (PLD) in Combination Versus PLD Alone in Patients With Platinum-Resistant Ovarian Cancer
Published in Journal of clinical oncology (10-12-2013)“…Vintafolide (EC145) is a folic acid-desacetylvinblastine conjugate that binds to the folate receptor (FR), which is expressed on the majority of epithelial…”
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The Role of Colonoscopy and Radiological Procedures in the Management of Acute Lower Intestinal Bleeding
Published in Clinical gastroenterology and hepatology (01-04-2010)“…There are multiple strategies for evaluating and treating lower intestinal bleeding (LIB). Colonoscopy has become the preferred initial test for most patients…”
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Phase Ib Study of Navicixizumab Plus Paclitaxel in Patients With Platinum-Resistant Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Published in Journal of clinical oncology (10-08-2022)“…This phase Ib study evaluated the safety and efficacy of paclitaxel plus navicixizumab, a bispecific antiangiogenic antibody to vascular endothelial growth…”
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Phase II study of treatment of advanced ovarian cancer with folate-receptor-targeted therapeutic (vintafolide) and companion SPECT-based imaging agent (99mTc-etarfolatide)
Published in Annals of oncology (01-04-2014)“…This report examines 99mTc-etarfolatide imaging to identify the presence of folate receptor (FR) on tumors of women with recurrent/refractory ovarian or…”
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Workplace Harassment and Discrimination in Gynecology: Results of the AAGL Member Survey
Published in Journal of minimally invasive gynecology (01-07-2019)“…To characterize workplace and sexual harassment and discrimination among physicians in gynecology. A beta-tested Internet survey was distributed by e-mail…”
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Anti-cancer therapy and clinical trial considerations for gynecologic oncology patients during the COVID-19 pandemic crisis
Published in Gynecologic oncology (01-07-2020)“…The COVID-19 pandemic has consumed considerable resources and has impacted the delivery of cancer care. Patients with cancer may have factors which place them…”
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