Search Results - "Naule, Lydie"
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Puberty, A Sensitive Window of Hypothalamic Development and Plasticity
Published in Endocrinology (Philadelphia) (01-01-2021)“…Abstract Puberty is a developmental period characterized by a broad range of physiologic changes necessary for the acquisition of adult sexual and reproductive…”
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Developmental exposure to environmentally relevant doses of phthalates alters the neural control of male and female reproduction in mice
Published in Environmental research (01-10-2024)“…The present study aims to analyze the effects of developmental exposure to phthalates at environmentally relevant doses on the neural control of male and…”
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Reproductive function and behaviors: an update on the role of neural estrogen receptors alpha and beta
Published in Frontiers in endocrinology (Lausanne) (24-06-2024)“…Infertility is becoming a major public health problem, with increasing frequency due to medical, environmental and societal causes. The increasingly late age…”
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Neuroendocrine and behavioral effects of maternal exposure to oral bisphenol A in female mice
Published in Journal of endocrinology (01-03-2014)“…Bisphenol A (BPA) is a widespread estrogenic compound. We investigated the effects of maternal exposure to BPA at reference doses on sexual behavior and…”
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Evolutionary Conservation of MKRN3 and Other Makorins and Their Roles in Puberty Initiation and Endocrine Functions
Published in Seminars in reproductive medicine (01-07-2019)“…Puberty is a critical period of development regulated by genetic, nutritional, and environmental factors. The role of ( ) in the regulation of pubertal timing…”
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Hypothalamic Overexpression of Makorin Ring Finger Protein 3 Results in Delayed Puberty in Female Mice
Published in Endocrinology (Philadelphia) (01-11-2022)“…Abstract Makorin ring finger protein 3 (MKRN3) is an important neuroendocrine player in the control of pubertal timing and upstream inhibitor of…”
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Sex-specific pubertal and metabolic regulation of Kiss1 neurons via Nhlh2
Published in eLife (08-09-2021)“…Hypothalamic Kiss1 neurons control gonadotropin-releasing hormone release through the secretion of kisspeptin. Kiss1 neurons serve as a nodal center that…”
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Mouse Testicular Mkrn3 Expression Is Primarily Interstitial, Increases Peripubertally, and Is Responsive to LH/hCG
Published in Endocrinology (Philadelphia) (01-09-2023)“…Abstract Studies in humans and mice support a role for Makorin RING finger protein 3 (MKRN3) as an inhibitor of gonadotropin-releasing hormone (GnRH) secretion…”
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Vulnerability of the Neural Circuitry Underlying Sexual Behavior to Chronic Adult Exposure to Oral Bisphenol A in Male Mice
Published in Endocrinology (Philadelphia) (01-02-2014)“…There are human reproduction concerns associated with extensive use of bisphenol A (BPA)-containing plastic and, in particular, the leaching of BPA into food…”
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Revisiting the neural role of estrogen receptor beta in male sexual behavior by conditional mutagenesis
Published in Hormones and behavior (01-04-2016)“…Estradiol derived from neural aromatization of gonadal testosterone plays a key role in the perinatal organization of the neural circuitry underlying male…”
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Delayed pubertal onset and prepubertal Kiss1 expression in female mice lacking central oestrogen receptor beta
Published in Human molecular genetics (20-12-2015)“…Ovarian oestradiol is essential for pubertal maturation and adult physiology of the female reproductive axis. It acts at central and peripheral sites through…”
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A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health
Published in Critical reviews in toxicology (22-10-2024)“…Bisphenol A (BPA), a synthetic chemical widely used in the production of polycarbonate plastic and epoxy resins, has been associated with a variety of adverse…”
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Effects of neural estrogen receptor beta deletion on social and mood-related behaviors and underlying mechanisms in male mice
Published in Scientific reports (10-04-2020)“…Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors…”
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Deletion of neural estrogen receptor alpha induces sex differential effects on reproductive behavior in mice
Published in Communications biology (20-04-2022)“…Estrogen receptor (ER) α is involved in several estrogen-modulated neural and peripheral functions. To determine its role in the expression of female and male…”
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MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity
Published in JCI insight (24-04-2023)“…Makorin ring finger protein 3 (MKRN3) was identified as an inhibitor of puberty initiation with the report of loss-of-function mutations in association with…”
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FRI281 Sexual Dimorphism In The LH Responses To Kisspeptin And Senktide Administration In Prepubertal Mice
Published in Journal of the Endocrine Society (05-10-2023)“…Disclosure: L. Maione: Consulting Fee; Self; Pfizer, Inc., Ipsen. L. Naule: None. C. Li: None. M. Magnuson: None. J. Young: Consulting Fee; Self; Serono…”
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OR09-01 Mini-Puberty Could Be A Key Phase Regulating Reproductive Function In Female Mice
Published in Journal of the Endocrine Society (05-10-2023)“…Disclosure: M. Chester: None. M. Devillers: None. L. Naule: None. F. Souaré: None. R. Corre: None. D. Quintas: None. C. Petrovic: None. J. Cohen-Tannoudji:…”
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OR08-3 The Role Of Neuronal Plasticity In The Timing Of Puberty Onset: Insights From A Mkrn3 Deficient Mouse Model
Published in Journal of the Endocrine Society (30-04-2019)“…Makorin ring finger protein 3 (MKRN3) was identified as a regulator of puberty initiation with the report of loss-of-function mutations in association with…”
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Vulnerability of the Neural Circuitry Underlying Sexual Behavior to Chronic Adult Exposure to Oral Bisphenol A in Male Mice
Published in Endocrinology (Philadelphia) (01-02-2014)“…There are human reproduction concerns associated with extensive use of bisphenol A (BPA)-containing plastic and, in particular, the leaching of BPA into food…”
Get full text
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