Search Results - "Nau, Christoph"
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Size matters: Effect of granule size of the bone graft substitute (Herafill®) on bone healing using Masquelet's induced membrane in a critical size defect model in the rat's femur
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-05-2020)“…The Masquelet technique for the treatment of large bone defects is a two‐stage procedure based on an induced membrane. The size of a scaffold is reported to be…”
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Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans
Published in Journal of translational medicine (15-11-2016)“…Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP)…”
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Human Acellular Collagen Matrices-Clinical Opportunities in Tissue Replacement
Published in International journal of molecular sciences (28-06-2024)“…The field of regenerative medicine is increasingly in need of effective and biocompatible materials for tissue engineering. Human acellular dermal matrix…”
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Nonunions of the humerus – Treatment concepts and results of the last five years
Published in Chinese journal of traumatology (01-08-2019)“…Fractures of the humerus account for 5%–8% of all fractures. Nonunion is found with an incidence of up to 15%, depending on the location of the fracture. In…”
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Enhancement of a one-step membrane technique for the treatment of large bone defects by pre-seeding the membrane with CD8 lymphocyte depleted bone marrow mononuclear cells in a rat femoral defect model
Published in Frontiers in immunology (23-10-2024)“…Background The one-step membrane technique, using a human acellular dermal matrix (hADM), is an experimental method for treating large bone defects. This…”
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Impact of scaffold granule size use in Masquelet technique on periosteal reaction: a study in rat femur critical size bone defect model
Published in European journal of trauma and emergency surgery (Munich : 2007) (01-02-2022)“…Purpose The Masquelet technique for the treatment of large bone defects is a two-stage procedure based on an induced membrane. Compared to mature periosteum,…”
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High calcium bioglass enhances differentiation and survival of endothelial progenitor cells, inducing early vascularization in critical size bone defects
Published in PloS one (14-11-2013)“…Early vascularization is a prerequisite for successful bone healing and endothelial progenitor cells (EPC), seeded on appropriate biomaterials, can improve…”
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The Impact of Defect Size on Bone Healing in Critical-Size Bone Defects Investigated on a Rat Femur Defect Model Comparing Two Treatment Methods
Published in Bioengineering (Basel) (01-03-2024)“…Critical-size bone defects up to 25 cm can be treated successfully using the induced membrane technique established by Masquelet. To shorten this procedure,…”
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First Human Leucocyte Antigen (HLA) Response and Safety Evaluation of Fibrous Demineralized Bone Matrix in a Critical Size Femoral Defect Model of the Sprague-Dawley Rat
Published in Materials (13-07-2020)“…Treatment of large bone defects is one of the great challenges in contemporary orthopedic and traumatic surgery. Grafts are necessary to support bone healing…”
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Secondary Angio-Embolization After Emergent Pelvic Stabilization and Pelvic Packing Is a Safe Option for Patients With Persistent Hemorrhage From Unstable Pelvic Ring Injuries
Published in Frontiers in surgery (17-12-2020)“…In patients with severe pelvic ring injuries, exsanguination still is the leading cause of death in the early post-injury phase. While mechanical pelvic ring…”
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One Stage Masquelets Technique: Evaluation of Different Forms of Membrane Filling with and without Bone Marrow Mononuclear Cells (BMC) in Large Femoral Bone Defects in Rats
Published in Cells (Basel, Switzerland) (30-04-2023)“…The classic two-stage masquelet technique is an effective procedure for the treatment of large bone defects. Our group recently showed that one surgery could…”
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Notfall- und Polytraumaversorgung
Published in Der Unfallchirurg (01-10-2022)Get full text
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From two stages to one: acceleration of the induced membrane (Masquelet) technique using human acellular dermis for the treatment of non-infectious large bone defects
Published in European journal of trauma and emergency surgery (Munich : 2007) (01-04-2020)“…Introduction The induced membrane technique for the treatment of large bone defects is a two-step procedure. In the first operation, a foreign body membrane is…”
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Measuring Bone Healing: Parameters and Scores in Comparison
Published in Bioengineering (Basel) (26-08-2023)“…(1) Background: Bone healing is a complex process that can not be replicated in its entirety in vitro. Research on bone healing still requires the animal…”
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Determination of the effective dose of bone marrow mononuclear cell therapy for bone healing in vivo
Published in European journal of trauma and emergency surgery (Munich : 2007) (01-04-2020)“…Introduction Cell-based therapy by bone marrow mononuclear cells (BMC) in a large-sized bone defect has already shown improved vascularization and new bone…”
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Fibrous Demineralized Bone Matrix (DBM) Improves Bone Marrow Mononuclear Cell (BMC)-Supported Bone Healing in Large Femoral Bone Defects in Rats
Published in Cells (Basel, Switzerland) (19-05-2021)“…Regeneration of large bone defects is a major objective in trauma surgery. Bone marrow mononuclear cell (BMC)-supported bone healing was shown to be efficient…”
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Severe intraoperative vascular bleeding as main complication of acetabular fractures treated with plate osteosynthesis via the modified Stoppa approach
Published in Injury (01-07-2023)“…Acetabular fractures are challenging fractures and finding the best supportive treatment is complex. Many operative treatment options exist – one of them is…”
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Alteration of Masquelet's induced membrane characteristics by different kinds of antibiotic enriched bone cement in a critical size defect model in the rat's femur
Published in Injury (01-02-2016)“…Abstract The Masquelet technique for the treatment of large bone defects consists of a 2-stage procedure. In the first stage, a polymethylmethacrylate (PMMA)…”
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Characteristics and Injury Patterns in Electric-Scooter Related Accidents-A Prospective Two-Center Report from Germany
Published in Journal of clinical medicine (22-05-2020)“…Since the introduction of rental E-scooters in Germany in mid-June 2019, the safety of this new means of transport has been the subject of extensive public…”
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Thoracolumbar injuries: operative treatment: indications, techniques, timing and implant removal. Current practice
Published in European journal of trauma and emergency surgery (Munich : 2007) (27-08-2024)“…The operative treatment of thoracolumbar fractures is a rapidly evolving improvement in the care of patients with this injury after trauma. This article…”
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