Search Results - "Nature reviews. Gastroenterology & hepatology"

The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics by Salminen, Seppo, Collado, Maria Carmen, Endo, Akihito, Hill, Colin, Lebeer, Sarah, Quigley, Eamonn M. M., Sanders, Mary Ellen, Shamir, Raanan, Swann, Jonathan R., Szajewska, Hania, Vinderola, Gabriel

“…In 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial…”
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Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention by Huang, Daniel Q., El-Serag, Hashem B., Loomba, Rohit

“…One quarter of the global population is estimated to have nonalcoholic fatty liver disease (NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is…”
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Cholangiocarcinoma 2020: the next horizon in mechanisms and management by Banales, Jesus M., Marin, Jose J. G., Lamarca, Angela, Rodrigues, Pedro M., Khan, Shahid A., Roberts, Lewis R., Cardinale, Vincenzo, Carpino, Guido, Andersen, Jesper B., Braconi, Chiara, Calvisi, Diego F., Perugorria, Maria J., Fabris, Luca, Boulter, Luke, Macias, Rocio I. R., Gaudio, Eugenio, Alvaro, Domenico, Gradilone, Sergio A., Strazzabosco, Mario, Marzioni, Marco, Coulouarn, Cédric, Fouassier, Laura, Raggi, Chiara, Invernizzi, Pietro, Mertens, Joachim C., Moncsek, Anja, Ilyas, Sumera I., Heimbach, Julie, Koerkamp, Bas Groot, Bruix, Jordi, Forner, Alejandro, Bridgewater, John, Valle, Juan W., Gores, Gregory J.

“…Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence…”
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Advances in immunotherapy for hepatocellular carcinoma by Sangro, Bruno, Sarobe, Pablo, Hervás-Stubbs, Sandra, Melero, Ignacio

“…Hepatocellular carcinoma (HCC) is a prevalent disease with a progression that is modulated by the immune system. Systemic therapy is used in the advanced stage…”
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A global view of hepatocellular carcinoma: trends, risk, prevention and management by Yang, Ju Dong, Hainaut, Pierre, Gores, Gregory J., Amadou, Amina, Plymoth, Amelie, Roberts, Lewis R.

“…Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide. Risk factors for HCC include chronic hepatitis B and…”
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Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies by Keum, NaNa, Giovannucci, Edward

“…Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the second leading cause of cancer death. Arising through three major…”
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The role of short-chain fatty acids in microbiota–gut–brain communication by Dalile, Boushra, Van Oudenhove, Lukas, Vervliet, Bram, Verbeke, Kristin

“…Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract, are speculated to have…”
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Gut microbiota-derived metabolites as key actors in inflammatory bowel disease by Lavelle, Aonghus, Sokol, Harry

“…A key role of the gut microbiota in the establishment and maintenance of health, as well as in the pathogenesis of disease, has been identified over the past…”
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The four epidemiological stages in the global evolution of inflammatory bowel disease by Kaplan, Gilaad G., Windsor, Joseph W.

“…Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four epidemiological stages: Emergence, Acceleration in Incidence,…”
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The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics by Swanson, Kelly S., Gibson, Glenn R., Hutkins, Robert, Reimer, Raylene A., Reid, Gregor, Verbeke, Kristin, Scott, Karen P., Holscher, Hannah D., Azad, Meghan B., Delzenne, Nathalie M., Sanders, Mary Ellen

“…In May 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of nutritionists, physiologists and…”
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Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors by Klein, Alison P.

“…Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has more than doubled over the past 25 years. The highest incidence…”
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Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma by Llovet, Josep M., De Baere, Thierry, Kulik, Laura, Haber, Philipp K., Greten, Tim F., Meyer, Tim, Lencioni, Riccardo

“…Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality and has an increasing incidence worldwide. Locoregional therapies,…”
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Probiotics and prebiotics in intestinal health and disease: from biology to the clinic by Sanders, Mary Ellen, Merenstein, Daniel J., Reid, Gregor, Gibson, Glenn R., Rastall, Robert A.

“…Probiotics and prebiotics are microbiota-management tools for improving host health. They target gastrointestinal effects via the gut, although direct…”
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The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments by Targher, Giovanni, Corey, Kathleen E., Byrne, Christopher D., Roden, Michael

“…Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions worldwide. NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist…”
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Immunotherapy in colorectal cancer: rationale, challenges and potential by Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Diaz, Luis A.

“…Following initial successes in melanoma treatment, immunotherapy has rapidly become established as a major treatment modality for multiple types of solid…”
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Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders by Aron-Wisnewsky, Judith, Vigliotti, Chloé, Witjes, Julia, Le, Phuong, Holleboom, Adriaan G., Verheij, Joanne, Nieuwdorp, Max, Clément, Karine

“…Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes mellitus, two metabolic diseases strongly intertwined with non-alcoholic…”
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Pancreatic cancer stroma: an update on therapeutic targeting strategies by Hosein, Abdel N., Brekken, Rolf A., Maitra, Anirban

“…Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in the Western world with limited therapeutic options and dismal…”
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Liver regeneration: biological and pathological mechanisms and implications by Michalopoulos, George K., Bhushan, Bharat

“…The liver is the only solid organ that uses regenerative mechanisms to ensure that the liver-to-bodyweight ratio is always at 100% of what is required for body…”
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Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention by Younossi, Zobair, Anstee, Quentin M., Marietti, Milena, Hardy, Timothy, Henry, Linda, Eslam, Mohammed, George, Jacob, Bugianesi, Elisabetta

“…Key Points As a consequence of the pandemic spread of obesity, NAFLD is one of the most important causes of liver disease worldwide in adults and children,…”
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From NASH to HCC: current concepts and future challenges by Anstee, Quentin M., Reeves, Helen L., Kotsiliti, Elena, Govaere, Olivier, Heikenwalder, Mathias

“…Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and metabolic syndrome. The hepatic consequence of metabolic syndrome and…”
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