Search Results - "Nature biomedical engineering"

Data-efficient and weakly supervised computational pathology on whole-slide images by Lu, Ming Y., Williamson, Drew F. K., Chen, Tiffany Y., Chen, Richard J., Barbieri, Matteo, Mahmood, Faisal

“…Deep-learning methods for computational pathology require either manual annotation of gigapixel whole-slide images (WSIs) or large datasets of WSIs with…”
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The evolution of commercial drug delivery technologies by Vargason, Ava M., Anselmo, Aaron C., Mitragotri, Samir

“…Drug delivery technologies have enabled the development of many pharmaceutical products that improve patient health by enhancing the delivery of a therapeutic…”
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CRISPR-based diagnostics by Kaminski, Michael M., Abudayyeh, Omar O., Gootenberg, Jonathan S., Zhang, Feng, Collins, James J.

“…The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic intervention and epidemiological surveillance. Diagnostics based on…”
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A wearable electrochemical biosensor for the monitoring of metabolites and nutrients by Wang, Minqiang, Yang, Yiran, Min, Jihong, Song, Yu, Tu, Jiaobing, Mukasa, Daniel, Ye, Cui, Xu, Changhao, Heflin, Nicole, McCune, Jeannine S., Hsiai, Tzung K., Li, Zhaoping, Gao, Wei

“…Wearable non-invasive biosensors for the continuous monitoring of metabolites in sweat can detect a few analytes at sufficiently high concentrations, typically…”
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First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows by Hu, Zhenhua, Fang, Cheng, Li, Bo, Zhang, Zeyu, Cao, Caiguang, Cai, Meishan, Su, Song, Sun, Xingwang, Shi, Xiaojing, Li, Cong, Zhou, Tiejun, Zhang, Yuanxue, Chi, Chongwei, He, Pan, Xia, Xianming, Chen, Yue, Gambhir, Sanjiv Sam, Cheng, Zhen, Tian, Jie

“…The second near-infrared wavelength window (NIR-II, 1,000–1,700 nm) enables fluorescence imaging of tissue with enhanced contrast at depths of millimetres and…”
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Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA by Patchsung, Maturada, Jantarug, Krittapas, Pattama, Archiraya, Aphicho, Kanokpol, Suraritdechachai, Surased, Meesawat, Piyachat, Sappakhaw, Khomkrit, Leelahakorn, Nattawat, Ruenkam, Theerawat, Wongsatit, Thanakrit, Athipanyasilp, Niracha, Eiamthong, Bhumrapee, Lakkanasirorat, Benya, Phoodokmai, Thitima, Niljianskul, Nootaree, Pakotiprapha, Danaya, Chanarat, Sittinan, Homchan, Aimorn, Tinikul, Ruchanok, Kamutira, Philaiwarong, Phiwkaow, Kochakorn, Soithongcharoen, Sahachat, Kantiwiriyawanitch, Chadaporn, Pongsupasa, Vinutsada, Trisrivirat, Duangthip, Jaroensuk, Juthamas, Wongnate, Thanyaporn, Maenpuen, Somchart, Chaiyen, Pimchai, Kamnerdnakta, Sirichai, Swangsri, Jirawat, Chuthapisith, Suebwong, Sirivatanauksorn, Yongyut, Chaimayo, Chutikarn, Sutthent, Ruengpung, Kantakamalakul, Wannee, Joung, Julia, Ladha, Alim, Jin, Xin, Gootenberg, Jonathan S., Abudayyeh, Omar O., Zhang, Feng, Horthongkham, Navin, Uttamapinant, Chayasith

“…Nucleic acid detection by isothermal amplification and the collateral cleavage of reporter molecules by CRISPR-associated enzymes is a promising alternative to…”
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Explainable machine-learning predictions for the prevention of hypoxaemia during surgery by Lundberg, Scott M., Nair, Bala, Vavilala, Monica S., Horibe, Mayumi, Eisses, Michael J., Adams, Trevor, Liston, David E., Low, Daniel King-Wai, Newman, Shu-Fang, Kim, Jerry, Lee, Su-In

“…Although anaesthesiologists strive to avoid hypoxaemia during surgery, reliably predicting future intraoperative hypoxaemia is not possible at present. Here,…”
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Artificial intelligence in healthcare by Yu, Kun-Hsing, Beam, Andrew L., Kohane, Isaac S.

“…Artificial intelligence (AI) is gradually changing medical practice. With recent progress in digitized data acquisition, machine learning and computing…”
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An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid by Tehrani, Farshad, Teymourian, Hazhir, Wuerstle, Brian, Kavner, Jonathan, Patel, Ravi, Furmidge, Allison, Aghavali, Reza, Hosseini-Toudeshki, Hamed, Brown, Christopher, Zhang, Fangyu, Mahato, Kuldeep, Li, Zhengxing, Barfidokht, Abbas, Yin, Lu, Warren, Paul, Huang, Nickey, Patel, Zina, Mercier, Patrick P., Wang, Joseph

“…Implementations of wearable microneedle-based arrays of sensors for the monitoring of multiple biomarkers in interstitial fluid have lacked system integration…”
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An epidermal patch for the simultaneous monitoring of haemodynamic and metabolic biomarkers by Sempionatto, Juliane R., Lin, Muyang, Yin, Lu, De la paz, Ernesto, Pei, Kexin, Sonsa-ard, Thitaporn, de Loyola Silva, Andre N., Khorshed, Ahmed A., Zhang, Fangyu, Tostado, Nicholas, Xu, Sheng, Wang, Joseph

“…Monitoring the effects of daily activities on the physiological responses of the body calls for wearable devices that can simultaneously track metabolic and…”
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A soft neuroprosthetic hand providing simultaneous myoelectric control and tactile feedback by Gu, Guoying, Zhang, Ningbin, Xu, Haipeng, Lin, Shaoting, Yu, Yang, Chai, Guohong, Ge, Lisen, Yang, Houle, Shao, Qiwen, Sheng, Xinjun, Zhu, Xiangyang, Zhao, Xuanhe

“…Neuroprosthetic hands are typically heavy (over 400 g) and expensive (more than US$10,000), and lack the compliance and tactile feedback of human hands. Here,…”
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Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning by Poplin, Ryan, Varadarajan, Avinash V., Blumer, Katy, Liu, Yun, McConnell, Michael V., Corrado, Greg S., Peng, Lily, Webster, Dale R.

“…Traditionally, medical discoveries are made by observing associations, making hypotheses from them and then designing and running experiments to test the…”
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Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation by Yang, Zhaogang, Shi, Junfeng, Xie, Jing, Wang, Yifan, Sun, Jingyao, Liu, Tongzheng, Zhao, Yarong, Zhao, Xiuting, Wang, Xinmei, Ma, Yifan, Malkoc, Veysi, Chiang, Chiling, Deng, Weiye, Chen, Yuanxin, Fu, Yuan, Kwak, Kwang J., Fan, Yamin, Kang, Chen, Yin, Changcheng, Rhee, June, Bertani, Paul, Otero, Jose, Lu, Wu, Yun, Kyuson, Lee, Andrew S., Jiang, Wen, Teng, Lesheng, Kim, Betty Y. S., Lee, L. James

“…Exosomes are attractive as nucleic-acid carriers because of their favourable pharmacokinetic and immunological properties and their ability to penetrate…”
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Synthetic data in machine learning for medicine and healthcare by Chen, Richard J., Lu, Ming Y., Chen, Tiffany Y., Williamson, Drew F. K., Mahmood, Faisal

“…The proliferation of synthetic data in artificial intelligence for medicine and healthcare raises concerns about the vulnerabilities of the software and the…”
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A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip by Jalili-Firoozinezhad, Sasan, Gazzaniga, Francesca S., Calamari, Elizabeth L., Camacho, Diogo M., Fadel, Cicely W., Bein, Amir, Swenor, Ben, Nestor, Bret, Cronce, Michael J., Tovaglieri, Alessio, Levy, Oren, Gregory, Katherine E., Breault, David T., Cabral, Joaquim M. S., Kasper, Dennis L., Novak, Richard, Ingber, Donald E.

“…The diverse bacterial populations that comprise the commensal microbiome of the human intestine play a central role in health and disease. A method that…”
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Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs by Yu, Jicheng, Wang, Jinqiang, Zhang, Yuqi, Chen, Guojun, Mao, Weiwei, Ye, Yanqi, Kahkoska, Anna R., Buse, John B., Langer, Robert, Gu, Zhen

“…Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could enhance health and improve quality of life for people with type 1…”
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy by Rodell, Christopher B., Arlauckas, Sean P., Cuccarese, Michael F., Garris, Christopher S., Li, Ran, Ahmed, Maaz S., Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph

“…Tumour-associated macrophages are abundant in many cancers, and often display an immune-suppressive M2-like phenotype that fosters tumour growth and promotes…”
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Pre-symptomatic detection of COVID-19 from smartwatch data by Mishra, Tejaswini, Wang, Meng, Metwally, Ahmed A., Bogu, Gireesh K., Brooks, Andrew W., Bahmani, Amir, Alavi, Arash, Celli, Alessandra, Higgs, Emily, Dagan-Rosenfeld, Orit, Fay, Bethany, Kirkpatrick, Susan, Kellogg, Ryan, Gibson, Michelle, Wang, Tao, Hunting, Erika M., Mamic, Petra, Ganz, Ariel B., Rolnik, Benjamin, Li, Xiao, Snyder, Michael P.

“…Consumer wearable devices that continuously measure vital signs have been used to monitor the onset of infectious disease. Here, we show that data from…”
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Wireless and battery-free technologies for neuroengineering by Won, Sang Min, Cai, Le, Gutruf, Philipp, Rogers, John A.

“…Tethered and battery-powered devices that interface with neural tissues can restrict natural motions and prevent social interactions in animal models, thereby…”
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy by Rodell, Christopher B, Arlauckas, Sean P, Cuccarese, Michael F, Garris, Christopher S, Li, Ran, Ahmed, Maaz S, Kohler, Rainer H, Pittet, Mikael J, Weissleder, Ralph

“…Tumour-associated macrophages are abundant in many cancers, and often display an immune-suppressive M2-like phenotype that fosters tumour growth and promotes…”
Get full text