Search Results - "Natsheh, Iyad"

The dark side of drug repurposing. From clinical trial challenges to antimicrobial resistance: analysis based on three major fields by Natsheh, Iyad Y, Alsaleh, Majd M, Alkhawaldeh, Ahmad K, Albadawi, Duaa K, Darwish, Maisa' M, Shammout, Mohammed Jamal A

“…Drug repurposing is a strategic endeavor that entails the identification of novel therapeutic applications for pharmaceuticals that are already available in…”
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Inhibition of Acinetobacter baumannii Biofilm Formation Using Different Treatments of Silica Nanoparticles by Natsheh, Iyad Y., Elkhader, Mallak T., Al-Bakheit, Ala’a A., Alsaleh, Majd M., El-Eswed, Bassam I., Hosein, Nedaa F., Albadawi, Duaa K.

“…There exists a multitude of pathogens that pose a threat to human and public healthcare, collectively referred to as ESKAPE pathogens. These pathogens are…”
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Dyes Are the Rainbow of Our Health by Shammout, Mohammad-Jamal A., Alsaleh, Majd M., Natsheh, Iyad Y., Albadawi, Duaa K., Alkhawaldeh, Ahmad K.

“…Natural dyes, obtained without the use of chemical treatment, are derived from naturally occurring sources, such as plants, animals, insects, and minerals. The…”
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Detection of Some Heavy Metals Used in the Surface Soil (Sediments) from Khirbet Al-Samra in Jordan by Alkhawaldeh, Ahmad Khalaf, Natsheh, Iyad Y., Alsaleh, Majd M., Shatnawi, Mohamad, Shahrour, Wesam, Majdalawi, Majdi M., Alsarhan, Ali Ata

“…Al-Zarqa is facing difficulties with industry conversion and extensive urbanization. Spatial analysis was used to analyze the environmental quality of soil in…”
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Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells by Juengel, Eva, Engler, Johanna, Natsheh, Iyad, Jones, Jon, Mickuckyte, Ausra, Hudak, Lukasz, Jonas, Dietger, Blaheta, Roman A

“…Treatment options for metastatic renal cell carcinoma (RCC) are limited due to resistance to chemo- and radiotherapy. The development of small-molecule…”
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Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy by Engl, Tobias, Makarević, Jasmina, Relja, Borna, Natsheh, Iyad, Müller, Iris, Beecken, Wolf-Dietrich, Jonas, Dietger, Blaheta, Roman A

“…Tumor development remains one of the major obstacles following organ transplantation. Immunosuppressive drugs such as cyclosporine and tacrolimus directly…”
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Development of the sensitivity of nanostructured platinum electrodes by effect modified by adatoms (As, Sb, Pb and Sn) for electrocatalytic properties by Alkhawaldeh, Ahmad Khalf, Natsheh, Iyad Y., Alsaleh, Majd M., Shatnawi, Mohamad, Shahrour, Wesam, Majdalawi, Majdi M., Alsarhan, Ali Ata

“…Adatoms on metallic surfaces appear to be inexpensive reversible surface alloys. Platinum nanostructured electrode (PtNPs) opens up new avenues in…”
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Staphylococcus aureus epidemiology, pathophysiology, clinical manifestations and application of nano-therapeutics as a promising approach to combat methicillin resistant Staphylococcus aureus by Bashabsheh, Raghad H F, Al-Fawares, O'la, Natsheh, Iyad, Bdeir, Roba, Al-Khreshieh, Rozan O, Bashabsheh, Hasan H F

“…is a Gram-positive bacterium and one of the most prevalent infectious disease-related causes of morbidity and mortality in adults. This pathogen can trigger a…”
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HDAC-inhibition counteracts everolimus resistance in renal cell carcinoma in vitro by diminishing cdk2 and cyclin A by Juengel, Eva, Nowaz, Snigdha, Makarevi, Jasmina, Natsheh, Iyad, Werner, Isabella, Nelson, Karen, Reiter, Michael, Tsaur, Igor, Mani, Jens, Harder, Sebastian, Bartsch, Georg, Haferkamp, Axel, Blaheta, Roman A

“…Targeted therapies have improved therapeutic options of treating renal cell carcinoma (RCC). However, drug response is temporary due to resistance development…”
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Serum Biomarkers for Chemotherapy Cardiotoxicity Risk Detection of Breast Cancer Patients by Hasan, Diya, Ismail, Yazan, Al Tibi, Ahmad, Al-Zeidaneen, Safaa A, Odeh, Mohanad, Burghel, George J, Natsheh, Iyad, Abdelnour, Amid

“…This study aimed to investigate level fluctuations of serum biomarkers that are associated with cardiotoxicity risk, such as high-sensitivity C-reactive…”
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Inhibition of IAcinetobacter baumannii/I Biofilm Formation Using Different Treatments of Silica Nanoparticles by Natsheh, Iyad Y, Elkhader, Mallak T, Al-Bakheit, Ala’a A, Alsaleh, Majd M, El-Eswed, Bassam I, Hosein, Nedaa F, Albadawi, Duaa K

“…There exists a multitude of pathogens that pose a threat to human and public healthcare, collectively referred to as ESKAPE pathogens. These pathogens are…”
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Design, Synthesis, Anticancer Screening and Molecular Modelling Studies of Novel Thiazoles by Abu Nuwar, Mohammad, Jaradat, Da'san M. M., Chandrasekaran, Balakumar, Natsheh, Iyad, Rasras, Anas J., Alzubi, Mohammad S. H., Karpoormath, Rajshekhar, Khalili, Fawwaz, Hamadneh, Lama, Dahadha, Adnan A., Arafat, Tawfiq

“…Abstract A library of novel benzamide‐thiazolyl‐chalcone compounds was synthesized via Claisen‐Schmidt reaction and spectroscopically characterized using…”
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Mechanisms behind Temsirolimus Resistance Causing Reactivated Growth and Invasive Behavior of Bladder Cancer Cells In Vitro by Juengel, Eva, Natsheh, Iyad, Najafi, Ramin, Rutz, Jochen, Tsaur, Igor, Haferkamp, Axel, Chun, Felix K-H, Blaheta, Roman A

“…Although mechanistic target of rapamycin (mTOR) inhibitors, such as temsirolimus, show promise in treating bladder cancer, acquired resistance often hampers…”
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Modulation of the CXC-chemokine expression profile on tumor cells by the immunosuppressive drug mycophenolate mofetil by Engl, Tobias, Relja, Borna, Natsheh, Iyad, Makarevic, Jasmina, Müller, Iris, Beecken, Wolf-Dietrich, Jonas, Dietger, Blaheta, Roman A

“…The most undesirable complication of an effective immunosuppressive therapy is neoplastic tumor recurrence or the development of de novo cancer. Though the…”
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