Search Results - "Natoli, Mary"
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Sample-to-answer, extraction-free, real-time RT-LAMP test for SARS-CoV-2 in nasopharyngeal, nasal, and saliva samples: Implications and use for surveillance testing
Published in PloS one (25-02-2022)“…The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected…”
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Journal Article -
2
Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings
Published in Lab on a chip (11-10-2017)“…Each day, approximately 830 women and 7400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require…”
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A multiplexed, allele-specific recombinase polymerase amplification assay with lateral flow readout for sickle cell disease detection
Published in Lab on a chip (20-08-2024)“…Isothermal nucleic acid amplification tests have the potential to improve disease diagnosis at the point of care, but it remains challenging to develop…”
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4
Allele-Specific Recombinase Polymerase Amplification to Detect Sickle Cell Disease in Low-Resource Settings
Published in Analytical chemistry (Washington) (23-03-2021)“…Sickle cell disease (SCD) is a group of common, life-threatening disorders caused by a point mutation in the β globin gene. Early diagnosis through newborn and…”
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5
An integrated isothermal nucleic acid amplification test to detect HPV16 and HPV18 DNA in resource-limited settings
Published in Science translational medicine (21-06-2023)“…High-risk human papillomavirus (HPV) DNA testing is widely acknowledged as the most sensitive cervical cancer screening method but has limited availability in…”
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Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay
Published in Analytical biochemistry (01-03-2018)“…Regular HIV-1 viral load monitoring is the standard of care to assess antiretroviral therapy effectiveness in resource-rich settings. Persistently elevated…”
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7
Enzymatic activity preservation and protection through entrapment within degradable hydrogels
Published in Biotechnology and bioengineering (01-11-2013)“…ABSTRACT This work aims to develop a repeatable enzyme entrapment method that preserves activity within an amicable environment while resisting activity…”
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Improving Performance of a SARS-CoV-2 RT-LAMP Assay for Use With a Portable Isothermal Fluorimeter: Towards a Point-of-Care Molecular Testing Strategy
Published in Journal of biomolecular techniques (01-09-2021)“…Frequent and accessible testing is a critical tool to contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To develop low-cost…”
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9
Rapid Modular Synthesis and Processing of Thiol–Ene Functionalized Styrene–Butadiene Block Copolymers
Published in Macromolecules (10-04-2012)“…Diblock and triblock copolymers of poly(styrene)-block-poly(1,2-butadiene) (PS/PB) and PS/PB/PS were modified by photochemical thiol–ene chemistry to process…”
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10
Simple and inexpensive quantification of ammonia in whole blood
Published in Molecular genetics and metabolism (01-06-2015)“…Quantification of ammonia in whole blood has applications in the diagnosis and management of many hepatic diseases, including cirrhosis and rare urea cycle…”
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Real-time isothermal nucleic acid amplification detection in resource-limited settings: a description of an open-source miniature fluorimeter
Published in The Lancet global health (01-03-2021)“…The detection and quantification of nucleic acids traditionally relies on PCR, which requires the use of expensive thermocyclers with integrated fluorescence…”
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Journal Article -
12
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) for point-of-care detection of SARS-CoV-2: a clinical study to evaluate agreement with RT-qPCR
Published in The Lancet global health (01-03-2021)“…The global COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the need for rapid, accurate, and…”
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Journal Article -
13
Allele-specific recombinase polymerase amplification for real-time detection of sickle cell anaemia in low-resource settings: evaluation of an isothermal nucleic acid amplification test to detect the βS globin point mutation in paediatric patients
Published in The Lancet global health (01-03-2021)“…Sickle cell anaemia is a common, life-threatening disorder caused by a point mutation in the β globin gene. The high cost and complexity of conventional…”
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Journal Article -
14
Open-Source Miniature Fluorimeter to Monitor Real-Time Isothermal Nucleic Acid Amplification Reactions in Resource-Limited Settings
Published in Journal of visualized experiments (03-02-2021)“…Traditional methods to detect and quantify nucleic acids rely on polymerase chain reaction (PCR) and require the use of expensive thermocyclers with integrated…”
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Journal Article -
15
Isothermal Nucleic Acid Assays for the Detection of HIV Drug Resistance and Sickle Cell Disease in Low-Resource Settings
Published 01-01-2020“…HIV treatment has become more widely available and effective in the past several decades, with major global health initiatives targeted at increasing…”
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Dissertation -
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Sample-to-answer, extraction-free, real-time RT-LAMP test for SARS-CoV-2 in nasopharyngeal, nasal, and saliva samples: Implications and use for surveillance testing
Published in PloS one (01-01-2022)“…The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected…”
Get full text
Journal Article -
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THE ACTUALISM OF GIOVANNI GENTILE AND ITS CRITIQUE BY MICHELE FEDERICO SCIACCA
Published 1973Get full text
Dissertation -
18
THE ACTUALISM OF GIOVANNI GENTILE AND ITS CRITIQUE BY MICHELE FEDERICO SCIACCA
Published 01-01-1973Get full text
Dissertation