Search Results - "Natoli, Mary"

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    Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings by Majors, Catherine E, Smith, Chelsey A, Natoli, Mary E, Kundrod, Kathryn A, Richards-Kortum, Rebecca

    Published in Lab on a chip (11-10-2017)
    “…Each day, approximately 830 women and 7400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require…”
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    Journal Article
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    A multiplexed, allele-specific recombinase polymerase amplification assay with lateral flow readout for sickle cell disease detection by Chang, Megan M, Natoli, Mary E, Wilkinson, Alexis F, Tubman, Venée N, Airewele, Gladstone E, Richards-Kortum, Rebecca R

    Published in Lab on a chip (20-08-2024)
    “…Isothermal nucleic acid amplification tests have the potential to improve disease diagnosis at the point of care, but it remains challenging to develop…”
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    Journal Article
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    Allele-Specific Recombinase Polymerase Amplification to Detect Sickle Cell Disease in Low-Resource Settings by Natoli, Mary E, Chang, Megan M, Kundrod, Kathryn A, Coole, Jackson B, Airewele, Gladstone E, Tubman, Venée N, Richards-Kortum, Rebecca R

    Published in Analytical chemistry (Washington) (23-03-2021)
    “…Sickle cell disease (SCD) is a group of common, life-threatening disorders caused by a point mutation in the β globin gene. Early diagnosis through newborn and…”
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    Journal Article
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    Paper-based detection of HIV-1 drug resistance using isothermal amplification and an oligonucleotide ligation assay by Natoli, Mary E., Rohrman, Brittany A., De Santiago, Carolina, van Zyl, Gert U., Richards-Kortum, Rebecca R.

    Published in Analytical biochemistry (01-03-2018)
    “…Regular HIV-1 viral load monitoring is the standard of care to assess antiretroviral therapy effectiveness in resource-rich settings. Persistently elevated…”
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    Journal Article
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    Enzymatic activity preservation and protection through entrapment within degradable hydrogels by Mariani, Angela M., Natoli, Mary E., Kofinas, Peter

    Published in Biotechnology and bioengineering (01-11-2013)
    “…ABSTRACT This work aims to develop a repeatable enzyme entrapment method that preserves activity within an amicable environment while resisting activity…”
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    Journal Article
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    Rapid Modular Synthesis and Processing of Thiol–Ene Functionalized Styrene–Butadiene Block Copolymers by Silverstein, Joshua S, Casey, Brendan J, Natoli, Mary E, Dair, Benita J, Kofinas, Peter

    Published in Macromolecules (10-04-2012)
    “…Diblock and triblock copolymers of poly­(styrene)-block-poly­(1,2-butadiene) (PS/PB) and PS/PB/PS were modified by photochemical thiol–ene chemistry to process…”
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    Journal Article
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    Simple and inexpensive quantification of ammonia in whole blood by Ayyub, Omar B., Behrens, Adam M., Heligman, Brian T., Natoli, Mary E., Ayoub, Joseph J., Cunningham, Gary, Summar, Marshall, Kofinas, Peter

    Published in Molecular genetics and metabolism (01-06-2015)
    “…Quantification of ammonia in whole blood has applications in the diagnosis and management of many hepatic diseases, including cirrhosis and rare urea cycle…”
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    Journal Article
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    Real-time isothermal nucleic acid amplification detection in resource-limited settings: a description of an open-source miniature fluorimeter by Coole, Jackson, Kortum, Alex, Tang, Yubo, Vohra, Imran, Natoli, Mary, Kundrod, Kathryn, Richards-Kortum, Rebecca

    Published in The Lancet global health (01-03-2021)
    “…The detection and quantification of nucleic acids traditionally relies on PCR, which requires the use of expensive thermocyclers with integrated fluorescence…”
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    Journal Article
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    Reverse transcription loop-mediated isothermal amplification (RT-LAMP) for point-of-care detection of SARS-CoV-2: a clinical study to evaluate agreement with RT-qPCR by Natoli, Mary, Kundrod, Kathryn, Chang, Megan, Smith, Chelsey, Paul, Sai, Eldin, Karen, Patel, Keyur, Baker, Ellen, Schmeler, Kathleen, Richards-Kortum, Rebecca

    Published in The Lancet global health (01-03-2021)
    “…The global COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the need for rapid, accurate, and…”
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    Journal Article
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    Open-Source Miniature Fluorimeter to Monitor Real-Time Isothermal Nucleic Acid Amplification Reactions in Resource-Limited Settings by Coole, Jackson, Kortum, Alex, Tang, Yubo, Vohra, Imran, Maker, Yajur, Kundrod, Kathryn, Natoli, Mary, Richards-Kortum, Rebecca

    Published in Journal of visualized experiments (03-02-2021)
    “…Traditional methods to detect and quantify nucleic acids rely on polymerase chain reaction (PCR) and require the use of expensive thermocyclers with integrated…”
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    Journal Article
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    Isothermal Nucleic Acid Assays for the Detection of HIV Drug Resistance and Sickle Cell Disease in Low-Resource Settings by Natoli, Mary Elizabeth

    Published 01-01-2020
    “…HIV treatment has become more widely available and effective in the past several decades, with major global health initiatives targeted at increasing…”
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    Dissertation
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