Search Results - "Nation, Daniel A."

Importance of Treatment Status in Links Between Type 2 Diabetes and Alzheimer's Disease by McIntosh, Elissa C, Nation, Daniel A

“…To investigate relationships among type 2 diabetes treatment, Alzheimer's disease(AD) biomarkers, and risk for dementia. Participants were from the Alzheimer's…”
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APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline by Montagne, Axel, Nation, Daniel A., Sagare, Abhay P., Barisano, Giuseppe, Sweeney, Melanie D., Chakhoyan, Ararat, Pachicano, Maricarmen, Joe, Elizabeth, Nelson, Amy R., D’Orazio, Lina M., Buennagel, David P., Harrington, Michael G., Benzinger, Tammie L. S., Fagan, Anne M., Ringman, John M., Schneider, Lon S., Morris, John C., Reiman, Eric M., Caselli, Richard J., Chui, Helena C., TCW, Julia, Chen, Yining, Pa, Judy, Conti, Peter S., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.

“…Vascular contributions to dementia and Alzheimer’s disease are increasingly recognized 1 – 6 . Recent studies have suggested that breakdown of the blood–brain…”
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Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction by Nation, Daniel A., Sweeney, Melanie D., Montagne, Axel, Sagare, Abhay P., D’Orazio, Lina M., Pachicano, Maricarmen, Sepehrband, Farshid, Nelson, Amy R., Buennagel, David P., Harrington, Michael G., Benzinger, Tammie L. S., Fagan, Anne M., Ringman, John M., Schneider, Lon S., Morris, John C., Chui, Helena C., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.

“…Vascular contributions to cognitive impairment are increasingly recognized 1 – 5 as shown by neuropathological 6 , 7 , neuroimaging 4 , 8 – 11 , and…”
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Cognitive benefits of angiotensin IV and angiotensin-(1–7): A systematic review of experimental studies by Ho, Jean K., Nation, Daniel A.

“…•Ang IV and Ang-(1–7) have shown neuroprotective in animal models of cerebral injury.•Ang IV and its analogs are linked to improved cognition in models of…”
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Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and older adults by Min, Jungwon, Rouanet, Jeremy, Martini, Alessandra Cadete, Nashiro, Kaoru, Yoo, Hyun Joo, Porat, Shai, Cho, Christine, Wan, Junxiang, Cole, Steve W., Head, Elizabeth, Nation, Daniel A., Thayer, Julian F., Mather, Mara

“…Slow paced breathing via heart rate variability (HRV) biofeedback stimulates vagus-nerve pathways that counter noradrenergic stress and arousal pathways that…”
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Blood Pressure Variability and Cerebral Perfusion Decline: A Post Hoc Analysis of the SPRINT MIND Trial by Sible, Isabel J, Nation, Daniel A

“…Background Blood pressure variability (BPV) is predictive of cerebrovascular disease and dementia, possibly though cerebral hypoperfusion. Higher BPV is…”
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Evaluation of enzyme immunoassay and radioimmunoassay methods for the measurement of plasma oxytocin by Szeto, Angela, McCabe, Philip M, Nation, Daniel A, Tabak, Benjamin A, Rossetti, Maria A, McCullough, Michael E, Schneiderman, Neil, Mendez, Armando J

“…There is increased interest in measuring peripheral oxytocin levels to better understand the role of this peptide in mammalian behavior, physiology, and…”
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Brainstem Volumetric Integrity in Preclinical and Prodromal Alzheimer's Disease by Dutt, Shubir, Li, Yanrong, Mather, Mara, Nation, Daniel A

“…Neuropathological studies have suggested the tau pathology observed in Alzheimer's disease (AD) originates in brainstem nuclei, but no studies to date have…”
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Blood-Brain Barrier Crossing Renin-Angiotensin Drugs and Cognition in the Elderly: A Meta-Analysis by Ho, Jean K., Moriarty, Frank, Manly, Jennifer J., Larson, Eric B., Evans, Denis A., Rajan, Kumar B., Hudak, Elizabeth M., Hassan, Lamiaa, Liu, Enwu, Sato, Nobuyuki, Hasebe, Naoyuki, Laurin, Danielle, Carmichael, Pierre-Hugues, Nation, Daniel A.

“…Hypertension is an established risk factor for cognitive decline and dementia in older adults, highlighting the potential importance of antihypertensive…”
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Susceptibility of the conventional criteria for mild cognitive impairment to false-positive diagnostic errors by Edmonds, Emily C, Delano-Wood, Lisa, Clark, Lindsay R, Jak, Amy J, Nation, Daniel A, McDonald, Carrie R, Libon, David J, Au, Rhoda, Galasko, Douglas, Salmon, David P, Bondi, Mark W

“…Abstract Background We assessed whether mild cognitive impairment (MCI) subtypes could be empirically derived within the Alzheimer's Disease Neuroimaging…”
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Memory is preserved in older adults taking AT1 receptor blockers by Ho, Jean K, Nation, Daniel A

“…Prior work suggests that some but not all antihypertensive treatments may benefit cognition and risk for Alzheimer's disease, independent of stroke…”
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Brainstem substructures and cognition in prodromal Alzheimer’s disease by Dutt, Shubir, Li, Yanrong, Mather, Mara, Nation, Daniel A.

“…Neuropathological research suggests the tau pathology of Alzheimer’s disease may originate in brainstem nuclei, yet it remains unknown whether tau-mediated…”
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Pulse pressure in relation to tau-mediated neurodegeneration, cerebral amyloidosis, and progression to dementia in very old adults by Nation, Daniel A, Edmonds, Emily C, Bangen, Katherine J, Delano-Wood, Lisa, Scanlon, Blake K, Han, S Duke, Edland, Steven D, Salmon, David P, Galasko, Douglas R, Bondi, Mark W

“…Increased pulse pressure associated with age-related arterial stiffening increases risk for Alzheimer dementia but the mechanism responsible for this…”
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Neuropsychological Decline Stratifies Dementia Risk in Cognitively Unimpaired and Impaired Older Adults by Ho, Jean K, Nation, Daniel A

“…Validation and widespread use of markers indicating decline in serial neuropsychological exams has remained elusive despite potential value in prognostic and…”
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Older adults with perivascular spaces exhibit cerebrovascular reactivity deficits by Kapoor, Arunima, Yew, Belinda, Jang, Jung Yun, Dutt, Shubir, Li, Yanrong, Alitin, John Paul M., Gaubert, Aimee, Ho, Jean K., Blanken, Anna E., Sible, Isabel J., Marshall, Anisa, Shao, Xingfeng, Mather, Mara, Wang, Danny J.J., Nation, Daniel A.

“…Perivascular spaces on brain magnetic resonance imaging (MRI) may indicate poor fluid drainage in the brain and have been associated with numerous neurological…”
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Reliability of beat-to-beat blood pressure variability in older adults by Lohman, Trevor, Sible, Isabel J., Shenasa, Fatemah, Engstrom, Allison C., Kapoor, Arunima, Alitin, John Paul M., Gaubert, Aimee, Thayer, Julian F., Ferrer, Farrah, Nation, Daniel A.

“…Blood pressure variability (BPV) is emerging as an important risk factor across numerous disease states, including cerebrovascular and neurodegenerative…”
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Platelet-derived growth factor-BB and white matter hyperintensity burden in APOE4 carriers by Kapoor, Arunima, Nation, Daniel A

“…The apolipoprotein-e4 (APOE4) gene increases risk for developing late-onset Alzheimer's disease (AD) and has been linked to increased microvascular…”
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Editorial: The importance of cognitive practice effects in aging neuroscience by Kremen, William S, Nation, Daniel A, Nyberg, Lars

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Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes by Bangen, Katherine J, Werhane, Madeleine L, Weigand, Alexandra J, Edmonds, Emily C, Delano-Wood, Lisa, Thomas, Kelsey R, Nation, Daniel A, Evangelista, Nicole D, Clark, Alexandra L, Liu, Thomas T, Bondi, Mark W

“…Type 2 diabetes mellitus (T2DM) increases risk for dementia, including Alzheimer's disease (AD). Many previous studies of brain changes underlying cognitive…”
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Aggregate effects of vascular risk factors on cerebrovascular changes in autopsy-confirmed Alzheimer's disease by Bangen, Katherine J, Nation, Daniel A, Delano-Wood, Lisa, Weissberger, Gali H, Hansen, Lawrence A, Galasko, Douglas R, Salmon, David P, Bondi, Mark W

“…Abstract We examined the relationships of antemortem vascular risk factors to postmortem cerebrovascular and Alzheimer's disease (AD) pathologies. Eighty-four…”
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