Search Results - "Nati, Romain"
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Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients
Published in Movement disorders (01-11-2005)“…In PD, the impact of nocturnal respiration on sleep continuity and architecture has not been systematically investigated by polysomnography (PSG). We performed…”
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Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions
Published in BMC biology (09-06-2020)“…Parkinson's disease (PD) is a systemic disease clinically defined by the degeneration of dopaminergic neurons in the brain. While alterations in the gut…”
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Dopamine Pathway and Parkinson's Risk Variants Are Associated with Levodopa‐Induced Dyskinesia
Published in Movement disorders (01-10-2024)“…Background Levodopa‐induced dyskinesia (LID) is a common adverse effect of levodopa, one of the main therapeutics used to treat the motor symptoms of…”
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Mixed effects models but not t-tests or linear regression detect progression of apathy in Parkinson's disease over seven years in a cohort: a comparative analysis
Published in BMC medical research methodology (24-08-2024)“…While there is an interest in defining longitudinal change in people with chronic illness like Parkinson's disease (PD), statistical analysis of longitudinal…”
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Levodopa-induced dyskinesia in Parkinson's disease: Insights from cross-cohort prognostic analysis using machine learning
Published in Parkinsonism & related disorders (01-09-2024)“…Prolonged levodopa treatment in Parkinson's disease (PD) often leads to motor complications, including levodopa-induced dyskinesia (LID). Despite continuous…”
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Cardiovascular history and risk of idiopathic Parkinson's disease: a cross-sectional observational study
Published in BMC neuroscience (08-07-2024)“…Parkinson's disease (PD), while often associated with its distinctive motor symptoms, can also exert a notable impact on the cardiovascular system due to the…”
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Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson’s study
Published in NPJ Parkinson's Disease (23-11-2023)“…Heterozygous variants in the glucocerebrosidase GBA1 gene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the GBAP1 pseudogene,…”
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Comprehensive blood metabolomics profiling of Parkinson’s disease reveals coordinated alterations in xanthine metabolism
Published in NPJ Parkinson's Disease (19-03-2024)“…Parkinson’s disease (PD) is a highly heterogeneous disorder influenced by several environmental and genetic factors. Effective disease-modifying therapies and…”
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Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome
Published in The journal of prevention of Alzheimer's disease (2024)“…Background With differences apparent in the gut microbiome in mild cognitive impairment (MCI) and dementia, and risk factors of dementia linked to alterations…”
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Integrating digital gait data with metabolomics and clinical data to predict outcomes in Parkinson’s disease
Published in NPJ digital medicine (06-09-2024)“…Parkinson’s disease (PD) presents diverse symptoms and comorbidities, complicating its diagnosis and management. The primary objective of this cross-sectional,…”
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Age at onset as stratifier in idiopathic Parkinson’s disease – effect of ageing and polygenic risk score on clinical phenotypes
Published in NPJ Parkinson's Disease (09-08-2022)“…Several phenotypic differences observed in Parkinson’s disease (PD) patients have been linked to age at onset (AAO). We endeavoured to find out whether these…”
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Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease
Published in NPJ Parkinson's Disease (06-04-2024)“…Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential…”
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Converging peripheral blood microRNA profiles in Parkinson's disease and progressive supranuclear palsy
Published in Brain communications (2024)“…MicroRNAs act via targeted suppression of messenger RNA translation in the DNA-RNA-protein axis. The dysregulation of microRNA(s) reflects the epigenetic…”
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Author Correction: Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson’s study
Published in NPJ Parkinson's Disease (18-12-2023)Get full text
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Bronchial airway gene expression in smokers with lung or head and neck cancer
Published in Cancer medicine (Malden, MA) (01-04-2014)“…Cigarette smoking is the major cause of cancers of the respiratory tract, including non‐small cell lung cancer (NSCLC) and head and neck cancer (HNC). In order…”
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Metoclopramide does not affect renal function and atrial natriuretic peptide release in response to acute saline loading in conscious rats
Published in Pharmacology (01-02-1994)“…It was previously shown in man that metoclopramide (MCP), a dopamine (DA)-2 receptor blocker, attenuates the natriuresis of water immersion. In the present…”
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