Search Results - "Nathens, A."

Fibrinogen in the initial resuscitation of severe trauma (FiiRST): a randomized feasibility trial by Nascimento, B., Callum, J., Tien, H., Peng, H., Rizoli, S., Karanicolas, P., Alam, A., Xiong, W., Selby, R., Garzon, A-M., Colavecchia, C., Howald, R., Nathens, A., Beckett, A.

“…Decreased plasma fibrinogen concentration shortly after injury is associated with higher blood transfusion needs and mortality. In North America and the UK,…”
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Compliance with a massive transfusion protocol (MTP) impacts patient outcome by Bawazeer, M, Ahmed, N, Izadi, H, McFarlan, A, Nathens, A, Pavenski, K

“…Abstract Background About 5% of civilian trauma requires massive transfusion. Protocolized resuscitation with blood products to achieve high plasma:RBC ratio…”
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Population‐based study of the impact of small bowel obstruction due to adhesions on short‐ and medium‐term mortality by Behman, R., Nathens, A. B., Haas, B., Look Hong, N., Pechlivanoglou, P., Karanicolas, P.

“…Background Small bowel obstruction due to adhesions (aSBO) is a common indication for admission to a surgical unit. Despite the prevalence of this condition,…”
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Population‐based study of the prevalence and management of self‐reported high pain scores in patients with non‐resected pancreatic adenocarcinoma by Tung, S., Coburn, N. G., Davis, L. E., Mahar, A. L., Myrehaug, S., Zhao, H., Earle, C. C., Nathens, A., Hallet, J.

“…Background Pain is a common debilitating symptom in pancreatic adenocarcinoma. This cohort study examined the use of, and factors associated with,…”
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The Effect of Organized Systems of Trauma Care on Motor Vehicle Crash Mortality by Nathens, Avery B, Jurkovich, Gregory J, Cummings, Peter, Rivara, Frederick P, Maier, Ronald V

“…CONTEXT Despite calls for wider national implementation of an integrated approach to trauma care, the effectiveness of this approach at a regional or state…”
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Early operative management in patients with adhesive small bowel obstruction: population‐based cost analysis by Behman, R., Nathens, A. B., Pechlivanoglou, P., Karanicolas, P., Jung, J., Look Hong, N.

“…Background Adhesive small bowel obstruction (aSBO) is a potentially recurrent disease. Although non‐operative management is often successful, it is associated…”
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Compliance with Evidence-Based Guidelines in Acute Pancreatitis: an Audit of Practices in University of Toronto Hospitals by Greenberg, J. A., Hsu, J., Bawazeer, M., Marshall, J., Friedrich, J. O., Nathens, A., Coburn, N., Huang, H., McLeod, R. S.

“…Despite existing evidence-based practice guidelines for the management of acute pancreatitis, clinical compliance with recommendations is poor. We conducted a…”
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First‐trimester maternal abdominal adiposity and adiponectin in pregnancy by De Souza, L. R., Retnakaran, R., Berger, H., Nathens, A. B., Maguire, J. L., Connelly, P. W., Park, A. L., Ray, J. G.

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Cryoprecipitate transfusion: assessing appropriateness and dosing in trauma by Nascimento, B., Rizoli, S., Rubenfeld, G., Fukushima, R., Ahmed, N., Nathens, A., Lin, Y., Callum, J.

“…Background: Originally developed for patients with congenital factor VIII deficiency, cryoprecipitate is currently largely used for acquired hypofibrinogenemia…”
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Hepatic fat and abdominal adiposity in early pregnancy together predict impaired glucose homeostasis in mid-pregnancy by De Souza, L R, Berger, H, Retnakaran, R, Vlachou, P A, Maguire, J L, Nathens, A B, Connelly, P W, Ray, J G

“…Hepatic fat and abdominal adiposity individually reflect insulin resistance, but their combined effect on glucose homeostasis in mid-pregnancy is unknown. A…”
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An evaluation of state firearm regulations and homicide and suicide death rates by Rosengart, M, Cummings, P, Nathens, A, Heagerty, P, Maier, R, Rivara, F

“…Objective: To determine if any of five different state gun laws were associated with firearm mortality: (1) “shall issue” laws permitting an individual to…”
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Regionalization of services improves access to emergency vascular surgical care by Roche-Nagle, G, Bachynski, K, Nathens, A B, Angoulvant, D, Rubin, B B

“…Management of vascular surgical emergencies requires rapid access to a vascular surgeon and hospital with the infrastructure necessary to manage vascular…”
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Neutrophil apoptosis is modulated by endothelial transmigration and adhesion molecule engagement by Watson, RW, Rotstein, OD, Nathens, AB, Parodo, J, Marshall, JC

“…Termination of a neutrophil-mediated inflammatory response occurs through the activation of the endogenous cell death program, apoptosis. Neutrophil apoptosis…”
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Relationship Between Trauma Center Volume and Outcomes by Nathens, Avery B, Jurkovich, Gregory J, Maier, Ronald V, Grossman, David C, MacKenzie, Ellen J, Moore, Maria, Rivara, Frederick P

“…CONTEXT The premise underlying regionalization of trauma care is that larger volumes of trauma patients cared for in fewer institutions will lead to improved…”
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Intracluster Correlation Coefficient and Multicenter Childhood Injury Research by Roudsari, B, Fowlers, R, Nathens, A

“…Purpose Design of a clustered childhood trauma study requires having an estimate of the variability in the outcome of interest between and within the clusters…”
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Thiol-mediated redox regulation of neutrophil apoptosis by William, R., Watson, G., Rotstein, Ori D., Nathens, Avery B., Dackiw, Alan P.B., Marshall, John C.

“…Background. Intracellular glutathione, an endogenous antioxidant, protects cellular function against oxidative stress. Because oxidative stress has been…”
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Tertiary Peritonitis: Clinical Features of a Complex Nosocomial Infection by Nathens, Avery B., Rotstein, Ori D., Marshall, John C.

“…The objective of this study was to define risk factors for and the clinical course of recurrent or tertiary peritonitis. Intensive supportive care of patients…”
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Selective decontamination of the digestive tract in surgical patients: a systematic review of the evidence by Nathens, A B, Marshall, J C

“…To determine the comparative efficacy of selective decontamination of the digestive tract in critically ill surgical and medical patients, and in selected…”
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Effect of an older sibling and birth interval on the risk of childhood injury by Nathens, Avery B, Neff, Margaret J, Goss, Christopher H, Maier, Ronald V, Rivara, Frederick P

“…Objective—Certain family structures have been identified as putting children at high risk for injury. To further define children at highest risk, we set out to…”
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Relevance and utility of peritoneal cultures in patients with peritonitis by Nathens, A B

“…The pathogenic organisms responsible for the manifestations of secondary peritonitis have been well characterized through almost 30 years of experimental and…”
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