Search Results - "Nathaniel Blair"
-
1
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice
Published in PloS one (31-01-2018)“…Forty million adults in the US suffer from anxiety disorders, making these the most common forms of mental illness. Transient receptor potential channel…”
Get full text
Journal Article -
2
Action Potential Broadening in Capsaicin-Sensitive DRG Neurons from Frequency-Dependent Reduction of Kv3 Current
Published in The Journal of neuroscience (04-10-2017)“…Action potential (AP) shape is a key determinant of cellular electrophysiological behavior. We found that in small-diameter, capsaicin-sensitive dorsal root…”
Get full text
Journal Article -
3
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
Published in Proceedings of the National Academy of Sciences - PNAS (14-05-2019)“…Transient receptor potential canonical type 6 (TRPC6) is a non-selective receptor-operated cation channel that regulates reactive fibrosis and growth…”
Get full text
Journal Article -
4
Benzoquinone reveals a cysteine-dependent desensitization mechanism of TRPA1
Published in Molecular pharmacology (01-05-2013)“…The transient receptor potential ankyrin 1 (TRPA1) nonselective cation channel has a conserved function as a noxious chemical sensor throughout much of…”
Get more information
Journal Article -
5
Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism
Published in The Journal of neuroscience (28-09-2005)“…Camphor is a naturally occurring compound that is used as a major active ingredient of balms and liniments supplied as topical analgesics. Despite its long…”
Get full text
Journal Article -
6
Intracellular calcium strongly potentiates agonist-activated TRPC5 channels
Published in The Journal of general physiology (01-05-2009)“…TRPC5 is a calcium (Ca(2+))-permeable nonselective cation channel expressed in several brain regions, including the hippocampus, cerebellum, and amygdala…”
Get full text
Journal Article -
7
Cost-effectiveness of antenatal multiple micronutrients and balanced energy protein supplementation compared to iron and folic acid supplementation in India, Pakistan, Mali, and Tanzania: A dynamic microsimulation study
Published in PLoS medicine (22-02-2022)“…Malnutrition among women of childbearing age is especially prevalent in Asia and sub-Saharan Africa and can be harmful to the fetus during pregnancy. In the…”
Get full text
Journal Article -
8
Roles of Tetrodotoxin (TTX)-Sensitive Na+ Current, TTX-Resistant Na+ Current, and Ca2+ Current in the Action Potentials of Nociceptive Sensory Neurons
Published in The Journal of neuroscience (01-12-2002)“…Nociceptive sensory neurons are unusual in expressing voltage-gated inward currents carried by sodium channels resistant to block by tetrodotoxin (TTX) as well…”
Get full text
Journal Article -
9
Role of Tetrodotoxin-Resistant Na+ Current Slow Inactivation in Adaptation of Action Potential Firing in Small-Diameter Dorsal Root Ganglion Neurons
Published in The Journal of neuroscience (12-11-2003)“…When acutely dissociated small-diameter dorsal root ganglion (DRG) neurons were stimulated with repeated current injections or prolonged application of…”
Get full text
Journal Article -
10
Naturally Produced Defensive Alkenal Compounds Activate TRPA1
Published in Chemical senses (01-05-2016)“…(E)-2-alkenals are aldehydes containing an unsaturated bond between the alpha and beta carbons. 2-alkenals are produced by many organisms for defense against…”
Get full text
Journal Article -
11
Simulated data for census-scale entity resolution research without privacy restrictions: a large-scale dataset generated by individual-based modeling
Published in Gates open research (2024)“…Entity resolution (ER) is the process of identifying and linking records that refer to the same real-world entity. ER is a fundamental challenge in data…”
Get full text
Journal Article -
12
Perceptual learning and the spatial frequency tuning of the perceptual template
Published in Journal of vision (Charlottesville, Va.) (01-09-2016)Get full text
Journal Article -
13
Oviposition site selection: unresponsiveness ofDrosophilato cues of potential thermal stress
Published in Animal behaviour (01-03-1997)“…Larvae ofDrosophila melanogasterinfest necrotic fruit, which the sun can heat to temperatures warm enough to kill or damage in-dwelling larvae. This study…”
Get full text
Journal Article -
14
Electrical Response Matrix of a Regular 2n-Gon
Published in Proceedings of the American Mathematical Society (01-06-2009)“…Consider a unit-resistive plate in the shape of a regular polygon with 2n sides, in which even-numbered sides are wired to electrodes and odd-numbered sides…”
Get full text
Journal Article -
15
Blocking and backward blocking involve learned inattention
Published in Psychonomic bulletin & review (01-12-2000)“…Four experiments examine blocking of associative learning by human participants in a disease diagnosis procedure. The results indicate that after a cue is…”
Get full text
Journal Article -
16
Cost-effectiveness of antenatal multiple micronutrients and balanced energy protein supplementation compared to iron and folic acid supplementation in India, Pakistan, Mali, and Tanzania: A dynamic microsimulation study
Published in PLoS medicine (01-02-2022)“…BackgroundMalnutrition among women of childbearing age is especially prevalent in Asia and sub-Saharan Africa and can be harmful to the fetus during pregnancy…”
Get full text
Journal Article -
17
The spatial footprint of the perceptual template
Published in Journal of vision (Charlottesville, Va.) (18-03-2010)“…Abstract only…”
Get full text
Journal Article -
18
Evaluation of token specificity in perceptual learning of phase discrimination
Published in Journal of vision (Charlottesville, Va.) (18-03-2010)“…Abstract only…”
Get full text
Journal Article -
19
-
20
Slow and stored light under conditions of electromagnetically induced transparency and four wave mixing in an atomic vapor
Published 01-01-2011“…The recent prospect of efficient, reliable, and secure quantum communication relies on the ability to coherently and reversibly map nonclassical states of…”
Get full text
Dissertation