Search Results - "Nathaniel, Diane"
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CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
Published in Neuron (Cambridge, Mass.) (23-10-2019)“…CRISPR/Cas9-based functional genomics have transformed our ability to elucidate mammalian cell biology. However, most previous CRISPR-based screens were…”
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Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
Published in The Journal of biological chemistry (13-12-2019)“…Intercellular propagation of protein aggregation is emerging as a key mechanism in the progression of several neurodegenerative diseases, including Alzheimer's…”
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A Subpopulation of Striatal Neurons Mediates Levodopa-Induced Dyskinesia
Published in Neuron (Cambridge, Mass.) (21-02-2018)“…Parkinson’s disease is characterized by the progressive loss of midbrain dopamine neurons. Dopamine replacement therapy with levodopa alleviates parkinsonian…”
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Abstract C117: [Advocate Abstract] Saving lives through advocacy
Published in Cancer epidemiology, biomarkers & prevention (01-06-2020)“…Abstract I am a stage 3 colon cancer survivor and patient advocate. My poster is a reflection of my experience with cancer and journey as a survivor. My life…”
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