Search Results - "Nathan, PJ"

Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of the recent advances in its pharmacology by Nathan, Pradeep J.

“…Hypericum possesses a unique pharmacology in that it displays the pharmacology of many classes of antidepressants and new mechanisms not typical of standard…”
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Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants by Stough, Con, Clarke, Jodi, Lloyd, Jenny, Nathan, Pradeep J.

“…Ginkgo biloba extract (EGb) from the world's oldest living tree has been reputed to ameliorate cognitive decline in the elderly and slow cognitive…”
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High-dose glycine impairs the prepulse inhibition measure of sensorimotor gating in humans by O’Neill, BV, Croft, RJ, Mann, C, Dang, O, Leung, S, Galloway, MP, Phan, KL, Nathan, PJ

“…An impaired capacity to filter or ‘gate’ sensory information is a core deficit in cognitive function associated with schizophrenia. These deficits have been…”
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Association between Amygdala Hyperactivity to Harsh Faces and Severity of Social Anxiety in Generalized Social Phobia by Phan, K. Luan, Fitzgerald, Daniel A., Nathan, Pradeep J., Tancer, Manuel E.

“…Previous functional brain imaging studies of social anxiety have implicated amygdala hyperactivity in response to social threat, though its relationship to…”
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Neural substrates for voluntary suppression of negative affect: A functional magnetic resonance imaging study by Phan, K. Luan, Fitzgerald, Daniel A., Nathan, Pradeep J., Moore, Gregory J., Uhde, Thomas W., Tancer, Manuel E.

“…Successful control of affect partly depends on the capacity to modulate negative emotional responses through the use of cognitive strategies. Although the…”
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Molecular Imaging of the Dopaminergic System and its Association with Human Cognitive Function by Cropley, Vanessa L., Fujita, Masahiro, Innis, Robert B., Nathan, Pradeep J.

“…Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) has recently been used to examine dopamine…”
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Subsensitive melatonin suppression by dim white light: possible biological marker of panic disorder by Nathan, Pradeep J., Burrows, Graham D., Norman, Trevor R.

“…Light is involved in providing entrainment of circadian rhythms and the suppression of the pineal hormone melatonin. In patients with affective disorders,…”
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Memory Correlates of Alzheimer's Disease Cerebrospinal Fluid Markers: A Longitudinal Cohort Study by Reijs, Babette L R, Ramakers, Inez H G B, Köhler, Sebastian, Teunissen, Charlotte E, Koel-Simmelink, Marleen, Nathan, Pradeep J, Tsolaki, Magda, Wahlund, Lars-Olof, Waldemar, Gunhild, Hausner, Lucrezia, Vandenberghe, Rik, Johannsen, Peter, Blackwell, Andrew, Vanderstichele, Hugo, Verhey, Frans, Visser, Pieter Jelle

“…Performance on episodic, semantic, and working memory tests is impaired in Alzheimer's disease (AD)-type dementia, but it is unclear which type of memory test…”
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Muscarinic and nicotinic receptors synergistically modulate working memory and attention in humans by Ellis, Julia R., Ellis, Kathryn A., Bartholomeusz, Cali F., Harrison, Ben J., Wesnes, Keith A., Erskine, Fiona F., Vitetta, Luis, Nathan, Pradeep J.

“…Functional abnormalities in muscarinic and nicotinic receptors are associated with a number of disorders including Alzheimer's disease and schizophrenia. While…”
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Gender differences in the cortical electrophysiological processing of visual emotional stimuli by Kemp, A.H, Silberstein, R.B, Armstrong, S.M, Nathan, P.J

“…The processing of visual emotional stimuli has been investigated previously; however, gender differences in the processing of emotional stimuli remain to be…”
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Muscarinic and nicotinic receptor modulation of object and spatial n-back working memory in humans by Green, Amity, Ellis, Kathryn A., Ellis, Julia, Bartholomeusz, Cali F., Ilic, Susan, Croft, Rodney J., Luan Phan, K., Nathan, Pradeep J.

“…Working memory impairments in the n-back task in schizophrenia have been linked to sustained deficiency in mesocortical dopamine function. More recently,…”
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The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects by STOUGH, C, LLOYD, J, CLARKE, J, DOWNEY, L. A, HUTCHISON, C. W, RODGERS, T, NATHAN, P. J

“…Extracts of Bacopa monniera have been reported to exert cognitive enhancing effects in animals. However, the effects on human cognition are inconclusive. The…”
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Functional connectivity during Stroop task performance by Harrison, Ben J., Shaw, Marnie, Yücel, Murat, Purcell, Rosemary, Brewer, Warrick J., Strother, Stephen C., Egan, Gary F., Olver, James S., Nathan, Pradeep J., Pantelis, Christos

“…Using covariance-based multivariate analysis, we examined patterns of functional connectivity in rCBF on a practice-extended version of the Stroop color-word…”
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Estrogen prevents 5-HT1A receptor-induced disruptions of prepulse inhibition in healthy women by Gogos, Andrea, Nathan, Pradeep J, Guille, Valérie, Croft, Rodney J, van den Buuse, Maarten

“…The sex steroid hormone, estrogen, has been proposed to be protective against schizophrenia. This study examined the effects of estrogen treatment on…”
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Augmenting serotonin neurotransmission with citalopram modulates emotional expression decoding but not structural encoding of moderate intensity sad facial emotional stimuli: an event-related potential (ERP) investigation by Labuschagne, I., Croft, RJ, Phan, KL, Nathan, PJ

“…Antidepressants targeting the serotonergic system have been shown to modulate biases in emotional processing. The effects of serotonergic modulation on the…”
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Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans by Kemp, Andrew H, Gray, Marcus A, Silberstein, Richard B, Armstrong, Stuart M, Nathan, Pradeep J

“…The serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however,…”
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The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans by Lu, Kristy, Gray, Marcus A., Oliver, Chris, Liley, David T., Harrison, Ben J., Bartholomeusz, Cali F., Phan, K. Luan, Nathan, Pradeep J.

“…L‐Theanine (δ‐glutamylethylamide) is one of the predominant amino acids ordinarily found in green tea, and historically has been used as a relaxing agent. The…”
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Direct evidence that acutely enhancing serotonin with the selective serotonin reuptake inhibitor citalopram modulates the loudness dependence of the auditory evoked potential (LDAEP) marker of central serotonin function by Nathan, Pradeep J., Segrave, Rebecca, Phan, K. Luan, O'Neill, Barry, Croft, Rodney J.

“…The loudness dependence of the auditory evoked potential (LDAEP) has been suggested as a reliable measure of central serotonin function in humans. The most…”
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Relationship between nicotinic receptors and cognitive function in early Alzheimer’s disease: A 2-[ 18F]fluoro-A-85380 PET study by Ellis, J.R., Villemagne, V.L., Nathan, P.J., Mulligan, R.S., Gong, S.J., Chan, J.G., Sachinidis, J., O’Keefe, G.J., Pathmaraj, K., Wesnes, K.A., Savage, G., Rowe, C.C.

“…Neuronal nicotinic acetylcholine receptors (nAChRs) are critical for higher order cognitive processes. Post-mortem studies suggest reductions in nAChRs…”
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Pindolol augmentation of selective serotonin reuptake inhibitors: Accounting for the variability of results of placebo-controlled double-blind studies in patients with major depression by Segrave, Rebecca, Nathan, Pradeep J.

“…Co‐administration of pindolol with SSRIs in patients with depression has been suggested as a way to both hasten and augment antidepressant response. Clinical…”
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