Search Results - "Nath Yadav, Paras"

Synthesis and comprehensive characterization with anticancer activity assessment of salicylaldehyde and 2-acetylphenol based chitosan thiosemicarbazones and their copper(II) complexes by Adhikari, Hari Sharan, Garai, Aditya, Khanal, Chetana, Yadav, Paras Nath

“…•Chitosan tailoring via the involvement of amino group at C2 position of the pyranose ring was utilized to get chitosan functionalized salicylaldehyde and…”
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Exploration of anticancer potency of N(4) thiomorpholinyl isatin/5-haloisatin thiosemicarbazones on coordination to Cu2+ ion by Kumar Singh, Narendra, Sharma, Shivani, Krishnakumar, Abarna, Kumar Choudhary, Ravinder, Kumbhar, Anupa A., Butcher, Raymond J., Raj Pokharel, Yuba, Nath Yadav, Paras

“…[Display omitted] •Copper (II) complexes of thiosemicarbazones exhibit prominent anti-proliferative activity toward MCF-7 and A431 cell lines.•Coordination of…”
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Synthesis of 5-hydroxyisatin thiosemicarbazones, spectroscopic investigation, protein-ligand docking, and in vitro anticancer activity by Chaudhary, Upendra, Kumar, Piyush, Sharma, Pratibha, Chikara, Anshul, Barua, Ayanti, Mahiya, Kuldeep, Adhikari Subin, Jhashanath, Nath Yadav, Paras, Raj Pokharel, Yuba

“…[Display omitted] •5-Hydroxyisatin TSC with modifications at the N (4) position were novel anti-cancer agents.•L6showed potent anticancer action on A431 cells…”
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Editorial: "Investigations into the use of organic and inorganic compounds as chemotherapeutic agents by Yadav, Paras Nath, Matesanz, Ana Isabel

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Synthesis, characterization, anticancer activity, molecular docking and DFT calculation of 3-acetylcoumarin thiosemicarbazones and Schiff’s bases by Yadav, Anand Kumar, Singh, Neeta, Silwal, Manoj, Adhikari, Achyut, Yadav, Paras Nath

“…[Display omitted] •Thiosemicarbazones (3a-d) of 3-acetylumbelliferone and Schiff’s bases (4a-b) of 3-acetylcoumarin were synthesized and characterized by…”
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5‑Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro by Shahi, Nerina, Yadav, Paras Nath, Chaudhary, Upendra, Saad, Mohd, Mahiya, Kuldeep, Khan, Arif, Shafi, Syed, Pokharel, Yuba Raj

“…A series of novel thiosemicarbazone derivatives containing 5-methoxy isatin were designed and synthesized with modification on N(4) position. Derivatives…”
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Zinc(II) complexes derived from pyridine-2-carbaldehyde thiosemicarbazone and (1 E)-1-pyridin-2-ylethan-1-one thiosemicarbazone. Synthesis, crystal structures and antiproliferative activity of zinc(II) complexes by Kovala-Demertzi, Dimitra, Yadav, Paras Nath, Wiecek, Joanna, Skoulika, Stauroula, Varadinova, Tatiana, Demertzis, Mavroudis A.

“…The complexes [ZnCl 2(HFoTsc) · H 2O], [Zn(FoTsc) 2], [ZnCl 2(HAcTsc) · H 2O] and [Zn(AcTsc) 2], where HFoTsc and HAcTsc is pyridine-2-carbaldehyde…”
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Anticancer potential of 3-hydroxypyridine-2-carboxaldehyde N(4)-methyl and pyrrolidinylthiosemicarbazones and their Zn(II) complexes in different cancers via targeting MAPK superfamily signaling pathway by Shahi, Nerina, Pandey, Vivek, Pathak, Ankita, Thapa, Ram Sundar, Pokhrel, Prabina, Pokharel, Yuba Raj, Yadav, Paras Nath

“…Schematic representation of mechanism of action of HHyPyPyrd on cancer cell proliferation. [Display omitted] Zinc(II) complexes of 3-hydroxy-2-formylpyridine…”
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Functionalization of chitosan polymer and their applications by Pokhrel, Shanta, Yadav, Paras Nath

“…The deacetylated derivative of chitin i.e. chitosan is an advantageous and interesting bioactive polymer. Despite its biodegradability, it consists of many…”
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Palladium(II) Complexes of the Thiosemicarbazone and N-Ethylthiosemicarbazone of 3-Hydroxypyridine-2-carbaldehyde: Synthesis, Properties, and X-Ray Crystal Structure by Demertzis, Mavroudis A., Yadav, Paras Nath, Kovala-Demertzi, Dimitra

“…Two novel, stable PdII complexes, compounds 3 and 4, of two 3‐hydroxypyridine‐2‐carbaldehyde thiosemicarbazones, 1 and 2, resp., were prepared from Li2PdCl4…”
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Palladium(II) complexes of 4-formylantipyrine N(3)-substituted thiosemicarbazones: first example of X-ray crystal structure and description of bonding properties by Yadav, Paras Nath, Demertzis, Mavroudis A., Kovala-Demertzi, Dimitra, Skoulika, Stavroula, West, Douglas X.

“…Reaction of 4-formylantipyrine with thiosemicarbazide, N(3)-methylthiosemicarbazide and N(3)-ethylthiosemicarbazide produced the expected thiosemicarbazones,…”
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Synthesis, characterization, and anticancer activity of chitosan functionalized isatin based thiosemicarbazones, and their copper(II) complexes by Adhikari, Hari Sharan, Garai, Aditya, Yadav, Paras Nath

“…The one-pot synthetic method of condensation of isatin and 5-chloroisatin on to amino group at C2 position of the pyranose ring chitosan in chitosan…”
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Anticancer potency of copper(II) complexes of thiosemicarbazones by Singh, Narendra Kumar, Kumbhar, Anupa A, Pokharel, Yuba Raj, Yadav, Paras Nath

“…Being a structural and catalytic cofactor in a number of biological pathways, copper accumulates in tumors owing to selective permeability of the cancer cell…”
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Synthesis, crystal structure, spectral properties and cytotoxic activity of platinum(II) complexes of 2-acetyl pyridine and pyridine-2-carbaldehyde N(4)-ethyl-thiosemicarbazones by Kovala-Demertzi, Dimitra, Yadav, Paras Nath, Demertzis, Mavroudis A, Coluccia, Mauro

“…The reactions of Na 2PtCl 4 with pyridine-2-carbaldehyde and 2-acetyl pyridine N(4)-ethyl-thiosemicarbazones, HFo4Et and HAc4Et respectively, afforded the…”
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Anticancer mechanism of coumarin-based derivatives by Yadav, Anand Kumar, Maharjan Shrestha, Ramina, Yadav, Paras Nath

“…The structural motif of coumarins is related with various biological activities and pharmacological properties. Both natural coumarin extracted from various…”
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Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action by Adhikari, Hari Sharan, Yadav, Paras Nath

“…Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups can give derivatives of enhanced solubility and remarkable anticancer…”
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Synthesis, characterization and antimicrobial activity of maltol functionalized chitosan derivatives by Saud, Rajendra, Pokhrel, Shanta, Yadav, Paras Nath

“…Chitin was isolated from prawn shell powder through demineralization and deproteinization process. Chitosan was synthesized from isolated chitin by…”
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Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde and their antibacterial activity by Yadav, Manoj Kumar, Pokhrel, Shanta, Yadav, Paras Nath

“…Chitosan was synthesized from chitin; extracted from prawn shells' powder via deacetylation and physicochemical properties were studied. Novel chitosan…”
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Synthesis, characterization, anticancer, pharmacokinetics and molecular docking investigation of N (4)-alkyl incorporated-3-acetyl-4-hydroxycoumarin thiosemicarbazones and their copper(II) complexes by Shrestha, Ramina Maharjan, Mahiya, Kuldeep, Shrestha, Asmita, Mohanty, Soumya Ranjan, Yadav, Sanjeev Kumar, Yadav, Paras Nath

“…•Synthesis and characterization: HACmMeTsc, HACmDEtTsc, [Cu(HACmMeTsc)Cl], [Cu(HACmEtTsc)Cl] and [Cu(HACmDEtTsc)Cl] .•[Cu(HACmMeTsc)Cl]: distorted square…”
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Synthesis, characterization, and anticancer potency of coumarin-derived thiosemicarbazones and their Copper(II) complexes by Shrestha, Ramina Maharjan, Mahiya, Kuldeep, Shrestha, Asmita, Mohanty, Soumya Ranjan, Yadav, Sanjeev Kumar, Yadav, Paras Nath

“…[Display omitted] •Coumarin Thiosemicarbazones: acidic hydrogen at N(1) involved in intramolecular hydrogen bonding with lactone carbonyl forming more stable E…”
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