Search Results - "Nath Neerukonda, Sabari"

Neutralizing Antibodies Targeting the Conserved Stem Region of Influenza Hemagglutinin by Nath Neerukonda, Sabari, Vassell, Russell, Weiss, Carol D

“…Influenza continues to be a public health threat despite the availability of annual vaccines. While vaccines are generally effective at inducing…”
Get full text

Kinome analyses of inflammatory responses to swine barn dust extract in human bronchial epithelial and monocyte cell lines by Nath Neerukonda, Sabari, Mahadev-Bhat, Sanjana, Aylward, Bridget, Johnson, Casey, Charavaryamath, Chandrashekhar, Arsenault, Ryan J

“…Exacerbated inflammation upon persistent barn organic dust exposure is a key contributor to the pathogenesis of lung inflammation and lung function decline…”
Get full text

Extracellular Vesicles from Red Blood Cells and Their Evolving Roles in Health, Coagulopathy and Therapy by Thangaraju, Kiruphagaran, Neerukonda, Sabari Nath, Katneni, Upendra, Buehler, Paul W

“…Red blood cells (RBCs) release extracellular vesicles (EVs) including both endosome-derived exosomes and plasma-membrane-derived microvesicles (MVs)…”
Get full text

A Review on SARS-CoV-2 Virology, Pathophysiology, Animal Models, and Anti-Viral Interventions by Neerukonda, Sabari Nath, Katneni, Upendra

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV…”
Get full text

Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and TMPRSS2 by Neerukonda, Sabari Nath, Vassell, Russell, Herrup, Rachel, Liu, Shufeng, Wang, Tony, Takeda, Kazuyo, Yang, Ye, Lin, Tsai-Lien, Wang, Wei, Weiss, Carol D

“…Pseudoviruses are useful surrogates for highly pathogenic viruses because of their safety, genetic stability, and scalability for screening assays. Many…”
Get full text

Interplay between RNA Viruses and Promyelocytic Leukemia Nuclear Bodies by Neerukonda, Sabari Nath

“…Promyelocytic leukemia nuclear bodies (PML NBs) are nuclear membrane-less sub structures that play a critical role in diverse cellular pathways including cell…”
Get full text

Avian Pattern Recognition Receptor Sensing and Signaling by Neerukonda, Sabari Nath, Katneni, Upendra

“…Pattern recognition receptors (PRRs) are a class of immune sensors that play a critical role in detecting and responding to several conserved patterns of…”
Get full text

SARS-CoV-2 BA.1 variant is neutralized by vaccine booster-elicited serum but evades most convalescent serum and therapeutic antibodies by Lusvarghi, Sabrina, Pollett, Simon D, Neerukonda, Sabari Nath, Wang, Wei, Wang, Richard, Vassell, Russell, Epsi, Nusrat J, Fries, Anthony C, Agan, Brian K, Lindholm, David A, Colombo, Christopher J, Mody, Rupal, Ewers, Evan C, Lalani, Tahaniyat, Ganesan, Anuradha, Goguet, Emilie, Hollis-Perry, Monique, Coggins, Si'Ana A, Simons, Mark P, Katzelnick, Leah C, Wang, Gregory, Tribble, David R, Bentley, Lisa, Eakin, Ann E, Broder, Christopher C, Erlandson, Karl J, Laing, Eric D, Burgess, Timothy H, Mitre, Edward, Weiss, Carol D

“…The rapid spread of the highly contagious Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) along with its high number of…”
Get more information

Effects of N-glycan modifications on spike expression, virus infectivity, and neutralization sensitivity in ancestral compared to Omicron SARS-CoV-2 variants by Lusvarghi, Sabrina, Stauft, Charles B, Vassell, Russell, Williams, Brittany, Baha, Haseebullah, Wang, Wei, Neerukonda, Sabari Nath, Wang, Tony, Weiss, Carol D

“…The SARS-CoV-2 spike glycoprotein has 22 potential N-linked glycosylation sites per monomer that are highly conserved among diverse variants, but how…”
Get full text

SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity by Neerukonda, Sabari Nath, Vassell, Russell, Lusvarghi, Sabrina, Wang, Richard, Echegaray, Fernando, Bentley, Lisa, Eakin, Ann E, Erlandson, Karl J, Katzelnick, Leah C, Weiss, Carol D, Wang, Wei

“…The SARS-CoV-2 B.1.617 lineage variants, Kappa (B.1.617.1) and Delta (B.1.617.2, AY) emerged during the second wave of infections in India, but the Delta…”
Get full text

Comparison of exosomes purified via ultracentrifugation (UC) and Total Exosome Isolation (TEI) reagent from the serum of Marek’s disease virus (MDV)-vaccinated and tumor-bearing chickens by Nath Neerukonda, Sabari, Egan, Nicholas A., Patria, Joseph, Assakhi, Imane, Tavlarides-Hontz, Phaedra, Modla, Shannon, Muñoz, Eric R., Hudson, Matthew B., Parcells, Mark S.

“…•Ultracentrifugation or TEI reagent purified particles conformed to exosome size.•TEI reagent yielded superior exosome recovery compared to…”
Get full text

A comparison of exosome purification methods using serum of Marek's disease virus (MDV)-vaccinated and -tumor-bearing chickens by Neerukonda, Sabari Nath, Egan, Nicholas A., Patria, Joseph, Assakhi, Imane, Tavlarides-Hontz, Phaedra, Modla, Shannon, Muñoz, Eric R., Hudson, Matthew B., Parcells, Mark S.

“…Marek's disease (MD) is an alphaherpesvirus (Marek's disease virus, MDV)-induced pathology of chickens associated with paralysis, immunosuppression,…”
Get full text

Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 Variants by Neerukonda, Sabari Nath, Wang, Richard, Vassell, Russell, Baha, Haseebullah, Lusvarghi, Sabrina, Liu, Shufeng, Wang, Tony, Weiss, Carol D., Wang, Wei

“…The SARS-CoV-2 Omicron variants were first detected in November 2021, and several Omicron lineages (BA.1, BA.2, BA.3, BA.4, and BA.5) have since rapidly…”
Get full text

Measuring Neutralizing Antibodies to SARS-CoV-2 Using Lentiviral Spike-Pseudoviruses by Neerukonda, Sabari Nath, Vassell, Russell, Weiss, Carol D, Wang, Wei

“…Assays measuring neutralizing antibodies (nAbs) against SARS-CoV-2 are used to evaluate serological responses after SARS-CoV-2 infection and the potency of…”
Get more information

Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects by Lusvarghi, Sabrina, Wang, Wei, Herrup, Rachel, Neerukonda, Sabari Nath, Vassell, Russell, Bentley, Lisa, Eakin, Ann E, Erlandson, Karl J, Weiss, Carol D

“…Mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants can compromise the effectiveness of therapeutic…”
Get full text

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants by Rothenberger, Sylvia, Hurdiss, Daniel L., Walser, Marcel, Malvezzi, Francesca, Mayor, Jennifer, Ryter, Sarah, Moreno, Hector, Liechti, Nicole, Bosshart, Andreas, Iss, Chloé, Calabro, Valérie, Cornelius, Andreas, Hospodarsch, Tanja, Neculcea, Alexandra, Looser, Thamar, Schlegel, Anja, Fontaine, Simon, Villemagne, Denis, Paladino, Maria, Schiegg, Dieter, Mangold, Susanne, Reichen, Christian, Radom, Filip, Kaufmann, Yvonne, Schaible, Doris, Schlegel, Iris, Zitt, Christof, Sigrist, Gabriel, Straumann, Marcel, Wolter, Julia, Comby, Marco, Sacarcelik, Feyza, Drulyte, Ieva, Lyoo, Heyrhyoung, Wang, Chunyan, Li, Wentao, Du, Wenjuan, Binz, H. Kaspar, Herrup, Rachel, Lusvarghi, Sabrina, Neerukonda, Sabari Nath, Vassell, Russell, Wang, Wei, Adler, Julia M., Eschke, Kathrin, Nascimento, Mariana, Abdelgawad, Azza, Gruber, Achim D., Bushe, Judith, Kershaw, Olivia, Knutson, Charles G., Balavenkatraman, Kamal K., Ramanathan, Krishnan, Wyler, Emanuel, Teixeira Alves, Luiz Gustavo, Lewis, Seth, Watson, Randall, Haeuptle, Micha A., Zürcher, Alexander, Dawson, Keith M., Steiner, Daniel, Weiss, Carol D., Amstutz, Patrick, van Kuppeveld, Frank J. M., Stumpp, Michael T., Bosch, Berend-Jan, Engler, Olivier, Trimpert, Jakob

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with potential resistance to existing drugs emphasizes the need for new…”
Get full text

Induction of the unfolded protein response (UPR) during Marek's disease virus (MDV) infection by Neerukonda, Sabari Nath, Katneni, Upendra K., Bott, Matthew, Golovan, Serguei P., Parcells, Mark S.

“…Marek's disease (MD) is a pathology of chickens associated with paralysis, immune suppression, and the rapid formation of T-cell lymphomas. MD is caused by the…”
Get full text

Comparison of the Transcriptomes and Proteomes of Serum Exosomes from Marek's Disease Virus-Vaccinated and Protected and Lymphoma-Bearing Chickens by Neerukonda, Sabari Nath, Tavlarides-Hontz, Phaedra, McCarthy, Fiona, Pendarvis, Kenneth, Parcells, Mark S

“…Marek's disease virus (MDV) is the causative agent of Marek's disease (MD), a complex pathology of chickens characterized by paralysis, immunosuppression, and…”
Get full text

Transcriptional Analyses of Innate and Acquired Immune Patterning Elicited by Marek's Disease Virus Vaccine Strains: Turkey Herpesvirus (HVT), Marek's Disease Virus 2 (strain SB1), and Bivalent Vaccines (HVT/SB1 and HVT-LT/SB1) by Neerukonda, Sabari Nath, Katneni, Upendra K, Bhandari, Nirajan, Parcells, Mark S

“…Marek's disease (MD) is a complex pathology of chickens caused by MD virus (MDV) 1 and is observed as paralysis, immune suppression, neurologic signs, and the…”
Get full text

Evaluation and validation of reference gene stability during Marek’s disease virus (MDV) infection by Neerukonda, Sabari Nath, Katneni, Upendra K., Golovan, Sergey, Parcells, Mark S.

“…•We examined the stability of (5) common housekeeping genes during Marek’s disease virus (MDV) infection: beta actin (BACT), 18S RNA, 28S RNA, GAPDH, and…”
Get full text