Search Results - "Natarajan, V"

Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment by Chan, Jennifer C., Morgan, Christopher P., Adrian Leu, N., Shetty, Amol, Cisse, Yasmine M., Nugent, Bridget M., Morrison, Kathleen E., Jašarević, Eldin, Huang, Weiliang, Kanyuch, Nickole, Rodgers, Ali B., Bhanu, Natarajan V., Berger, Dara S., Garcia, Benjamin A., Ament, Seth, Kane, Maureen, Neill Epperson, C., Bale, Tracy L.

“…Extracellular vesicles (EVs) are a unique mode of intercellular communication capable of incredible specificity in transmitting signals involved in cellular…”
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Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation by Dorighi, Kristel M., Swigut, Tomek, Henriques, Telmo, Bhanu, Natarajan V., Scruggs, Benjamin S., Nady, Nataliya, Still, Christopher D., Garcia, Benjamin A., Adelman, Karen, Wysocka, Joanna

“…Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at lysine 27 (H3K27ac) are correlated with transcriptionally engaged enhancer…”
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Sustained-release from nanocarriers: a review by Natarajan, Jayaganesh V., Nugraha, Chandra, Ng, Xu Wen, Venkatraman, Subbu

“…Nanocarriers have been explored for delivering drugs and other bioactive molecules for well over 35years. Since the introduction of Doxil®, a nanoliposomal…”
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Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance by Iglesias, Nahid, Paulo, Joao A., Tatarakis, Antonis, Wang, Xiaoyi, Edwards, Amanda L., Bhanu, Natarajan V., Garcia, Benjamin A., Haas, Wilhelm, Gygi, Steven P., Moazed, Danesh

“…Spatially and functionally distinct domains of heterochromatin and euchromatin play important roles in the maintenance of chromosome stability and regulation…”
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Characterization of histone acylations links chromatin modifications with metabolism by Simithy, Johayra, Sidoli, Simone, Yuan, Zuo-Fei, Coradin, Mariel, Bhanu, Natarajan V., Marchione, Dylan M., Klein, Brianna J., Bazilevsky, Gleb A., McCullough, Cheryl E., Magin, Robert S., Kutateladze, Tatiana G., Snyder, Nathaniel W., Marmorstein, Ronen, Garcia, Benjamin A.

“…Over the last decade, numerous histone acyl post-translational modifications (acyl-PTMs) have been discovered, of which the functional significance is still…”
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Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia by Farrelly, Lorna A., Zheng, Shuangping, Schrode, Nadine, Topol, Aaron, Bhanu, Natarajan V., Bastle, Ryan M., Ramakrishnan, Aarthi, Chan, Jennifer C, Cetin, Bulent, Flaherty, Erin, Shen, Li, Gleason, Kelly, Tamminga, Carol A., Garcia, Benjamin A., Li, Haitao, Brennand, Kristen J., Maze, Ian

“…Schizophrenia (SZ) is a psychiatric disorder with complex genetic risk dictated by interactions between hundreds of risk variants. Epigenetic factors, such as…”
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Epigenetic and Transcriptional Control of the Epidermal Growth Factor Receptor Regulates the Tumor Immune Microenvironment in Pancreatic Cancer by Li, Jinyang, Yuan, Salina, Norgard, Robert J, Yan, Fangxue, Sun, Yu H, Kim, Il-Kyu, Merrell, Allyson J, Sela, Yogev, Jiang, Yanqing, Bhanu, Natarajan V, Garcia, Benjamin A, Vonderheide, Robert H, Blanco, Andrés, Stanger, Ben Z

“…Although immunotherapy has revolutionized cancer care, patients with pancreatic ductal adenocarcinoma (PDA) rarely respond to these treatments, a failure that…”
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Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis by Sidoli, Simone, Bhanu, Natarajan V, Karch, Kelly R, Wang, Xiaoshi, Garcia, Benjamin A

“…Nucleosomes are the smallest structural unit of chromatin, composed of 147 base pairs of DNA wrapped around an octamer of histone proteins. Histone function is…”
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Crypto Deep Ring Topology Firewall in Sensitive Data Transmission and Retrieval in Cloud by K. Soman, Vikas, Natarajan, V

“…The data transmission and data retrieval process from the cloud is a critical issue because of cyber-attacks. The data in the cloud is highly vulnerable and…”
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Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 by Farrelly, Lorna A., Thompson, Robert E., Zhao, Shuai, Lepack, Ashley E., Lyu, Yang, Bhanu, Natarajan V., Zhang, Baichao, Loh, Yong-Hwee E., Ramakrishnan, Aarthi, Vadodaria, Krishna C., Heard, Kelly J., Erikson, Galina, Nakadai, Tomoyoshi, Bastle, Ryan M., Lukasak, Bradley J., Zebroski, Henry, Alenina, Natalia, Bader, Michael, Berton, Olivier, Roeder, Robert G., Molina, Henrik, Gage, Fred H., Shen, Li, Garcia, Benjamin A., Li, Haitao, Muir, Tom W., Maze, Ian

“…Chemical modifications of histones can mediate diverse DNA-templated processes, including gene transcription 1 – 3 . Here we provide evidence for a class of…”
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A new three-factor authentication and key agreement protocol for multi-server environment by Sudhakar, T., Natarajan, V.

“…Several password and smart-card based two-factor security remote user authentication protocols for multi-server environment have been proposed for the last two…”
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PDGF-BB overexpression in p53 null oligodendrocyte progenitors increases H3K27me3 and induces transcriptional changes which favor proliferation by Huang, Dennis, Mela, Angeliki, Bhanu, Natarajan V., Garcia, Benjamin A., Canoll, Peter, Casaccia, Patrizia

“…•OPCs lacking p53 form tumors when injected in mice only if they also express PDGF-BB.•PDGF-BB overexpression in p53 null OPC results in more proliferation,…”
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Lightweight key agreement protocol for IoT based on IKEv2 by Lavanya, M., Natarajan, V.

“…The future of wireless sensor networks is in providing IP connectivity to all the nodes in the network. 6LoWPAN is an adaptation layer which allows the IEEE…”
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Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription by Jih, Gloria, Iglesias, Nahid, Currie, Mark A., Bhanu, Natarajan V., Paulo, Joao A., Gygi, Steven P., Garcia, Benjamin A., Moazed, Danesh

“…Heterochromatin formation involves histone H3 methylation, with H3K9me2 defining a distinct heterochromatin state that is transcriptionally permissive and can…”
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PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation by Ren, Zhihong, Ahn, Jeong Hyun, Liu, Hequn, Tsai, Yi-Hsuan, Bhanu, Natarajan V., Koss, Brian, Allison, David F., Ma, Anqi, Storey, Aaron J., Wang, Ping, Mackintosh, Samuel G., Edmondson, Ricky D., Groen, RichardW.J., Martens, Anton C., Garcia, Benjamin A., Tackett, Alan J., Jin, Jian, Cai, Ling, Zheng, Deyou, Wang, Gang Greg

“…Dysregulation of polycomb repressive complex 2 (PRC2) promotes oncogenesis partly through its enzymatic function for inducing trimethylation of histone H3…”
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Recognition of Histone Crotonylation by Taf14 Links Metabolic State to Gene Expression by Gowans, Graeme J., Bridgers, Joseph B., Zhang, Jibo, Dronamraju, Raghuvar, Burnetti, Anthony, King, Devin A., Thiengmany, Aline V., Shinsky, Stephen A., Bhanu, Natarajan V., Garcia, Benjamin A., Buchler, Nicolas E., Strahl, Brian D., Morrison, Ashby J.

“…Metabolic signaling to chromatin often underlies how adaptive transcriptional responses are controlled. While intermediary metabolites serve as co-factors for…”
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Trivalent Gadolinium-Doped Diopside (CaMgSi2O6) for Photoluminescence and EPR Investigation by Singh, Vijay, Nandyala, Sooraj H., Natarajan, V., Joo, Ji Bong

“…Gd 3+ -doped CaMgSi 2 O 6 phosphors with varying dopant content were processed successfully using sol-gel preparation. Prepared products were verified by x-ray…”
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Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells by Gonzales-Cope, Michelle, Sidoli, Simone, Bhanu, Natarajan V, Won, Kyoung-Jae, Garcia, Benjamin A

“…Pluripotent cells can be differentiated into many different cell types in vitro. Successful differentiation is guided in large part by epigenetic reprogramming…”
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer by Zhang, Hanghang, Pandey, Somnath, Travers, Meghan, Sun, Hongxing, Morton, George, Madzo, Jozef, Chung, Woonbok, Khowsathit, Jittasak, Perez-Leal, Oscar, Barrero, Carlos A., Merali, Carmen, Okamoto, Yasuyuki, Sato, Takahiro, Pan, Joshua, Garriga, Judit, Bhanu, Natarajan V., Simithy, Johayra, Patel, Bela, Huang, Jian, Raynal, Noël J.-M., Garcia, Benjamin A., Jacobson, Marlene A., Kadoch, Cigall, Merali, Salim, Zhang, Yi, Childers, Wayne, Abou-Gharbia, Magid, Karanicolas, John, Baylin, Stephen B., Zahnow, Cynthia A., Jelinek, Jaroslav, Graña, Xavier, Issa, Jean-Pierre J.

“…Cyclin-dependent kinase 9 (CDK9) promotes transcriptional elongation through RNAPII pause release. We now report that CDK9 is also essential for maintaining…”
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High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin by Miller, Jeffery L, Tanno, Toshihiko, Bhanu, Natarajan V, Oneal, Patricia A, Goh, Sung-Ho, Staker, Pamela, Lee, Y Terry, Moroney, John W, Reed, Christopher H, Luban, Naomi LC, Wang, Rui-Hong, Eling, Thomas E, Childs, Richard, Ganz, Tomas, Leitman, Susan F, Fucharoen, Suthat

“…In thalassemia, deficient globin-chain production during erythropoiesis results in anemia. Thalassemia may be further complicated by iron overload (frequently…”
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