Search Results - "Natarajan, A.T"

From DNA damage to chromosome aberrations: Joining the break by Durante, M., Bedford, J.S., Chen, D.J., Conrad, S., Cornforth, M.N., Natarajan, A.T., van Gent, D.C., Obe, G.

“…Despite many years of experimental studies on radiation-induced chromosomal aberrations, and the recent progress in elucidating the molecular mechanisms of the…”
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Genotoxic effects of occupational exposure to lead and cadmium by Palus, J, Rydzynski, K, Dziubaltowska, E, Wyszynska, K, Natarajan, A.T, Nilsson, R

“…This study was designed to assess genotoxic damage in somatic cells of workers in a Polish battery plant after high-level occupational exposure to lead (Pb)…”
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IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans by Albertini, Richard J, Anderson, Diana, Douglas, George R, Hagmar, Lars, Hemminki, Kari, Merlo, Franco, Natarajan, A.T, Norppa, Hannu, Shuker, David E.G, Tice, Raymond, Waters, Michael D, Aitio, Antero

“…The purpose of these guidelines is to provide concise guidance on the planning, performing and interpretation of studies to monitor groups or individuals…”
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Chromosomal aberrations: formation, identification and distribution by OBE, G, PFEIFFER, P, SAVAGE, J. R. K, JOHANNES, C, GOEDECKE, W, JEPPESEN, P, NATARAJAN, A. T, MARTINEZ-LOPEZ, W, FOLLE, G. A, DRETS, M. E

“…Chromosomal aberrations (CA) are the microscopically visible part of a wide spectrum of DNA changes generated by different repair mechanisms of DNA double…”
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Chromosomal aberrations and sister chromatid exchanges in individuals exposed to arsenic through drinking water in West Bengal, India by Mahata, J., Basu, A., Ghoshal, S., Sarkar, J.N., Roy, A.K., Poddar, G., Nandy, A.K., Banerjee, A., Ray, K., Natarajan, A.T., Nilsson, R., Giri, A.K.

“…Arsenic contamination in groundwater has become a worldwide problem. Currently an unprecedented number of people in West Bengal, India and Bangladesh are…”
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Formation of chromosome aberrations: insights from FISH by Natarajan, A.T., Boei, J.J.W.A.

“…Most of the mutagenic and carcinogenic agents induce chromosome aberrations in vivo and in vitro. Conventional solid staining (such as Giemsa) has been…”
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Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells by van Hoffen, Anneke, Natarajan, A.T., Mayne, Lynne V., Zeeland, Albert A.van, Mullenders, Leon H.F., Venema, Jaap

“…Removal of ultraviolet light induced cyclobutane pyrimidine dimers (CPD) from active and inactive genes was analyzed in cells derived from patients suffering…”
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A proposed system for scoring structural aberrations detected by chromosome painting by Tucker, J D, Morgan, W F, Awa, A A, Bauchinger, M, Blakey, D, Cornforth, M N, Littlefield, L G, Natarajan, A T, Shasserre, C

“…The advent of chromosome painting has brought the realization that structural aberrations can be far more complicated than previously imagined. Various…”
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Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens by Natarajan, A T, Darroudi, F

“…An established human hepatoma cell strain (Hep G2) was used in micronuclei (MN) and sister chromatid exchange (SCE) assays to evaluate the clastogenic…”
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Application of FISH Chromosome Painting Assay for Dose Reconstruction: State of Art and Current Views by Darroudi, F., Natarajan, A.T.

“…Fluorescence in situ hybridisation (FISH) with chromosome-specific composite DNA probes, has been shown to be a valid method for quantifying structural stable…”
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Biological effect monitoring in industrial workers from the Czech Republic exposed to low levels of butadiene by Tates, A.D., van Dam, F.J., de Zwart, F.A., Darroudi, F., Natarajan, A.T., Rössner, P., Peterková, K., Peltonen, K., Demopoulos, N.A., Stephanou, G., Vlachodimitropoulos, D., Srám, R.J.

“…Blood samples were collected twice (in 1993 and 1994) from 19 workers exposed to 1,3-butadiene and 19 matched controls. Three exposed and three control…”
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Instability of CHO chromosomes containing interstitial telomeric sequences originating from Chinese hamster chromosome 10 by Slijepcevic, P, Xiao, Y, Natarajan, A T, Bryant, P E

“…We identified a marker chromosome in the CHO K1 cell line containing amplifications of interstitial telomeric sequences originating from Chinese hamster…”
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Chromosome aberrations: past, present and future by NATARAJAN, A. T

“…Spontaneous and induced chromosome aberrations have been studied over more than a century. The resolution of detection of aberrations has depended on the…”
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Radiosensitivity and repair of the inactive X-chromosome. Insights from FISH and immunocytogenetics by Surrallés, J, Natarajan, A.T

“…The inactive X-chromosome provides a unique opportunity to study the role of transcriptional activity and chromatin condensation in the repair of chromosome…”
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Frequencies of X-ray induced chromosome aberrations in lymphocytes of xeroderma pigmentosum and Fanconi anemia patients estimated by Giemsa and fluorescence in situ hybridization staining techniques by Saraswathy, Radha, Natarajan, A.T.

“…Blood lymphocytes from xeroderma pigmentosum (XP) and Fanconi anemia (FA) patients were assessed for their sensitivity to ionizing radiation by estimating the…”
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Induction, processing and persistence of radiation-induced chromosomal aberrations involving hamster euchromatin and heterochromatin by Puerto, S, Marcos, R, Ramı́rez, M.J, Creus, A, Boei, J.J.W.A, Meijers, M, Natarajan, A.T, Surrallés, J

“…Euchromatic and heterochromatic regions are easily distinguished in Chinese hamster sex chromosomes, hence offering the possibility of studying the role of…”
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Transcription affects the rate but not the extent of repair of cyclobutane pyrimidine dimers in the human adenosine deaminase gene by VENEMA, J, BARTOSOVA, Z, NATARAJAN, A.T, VAN ZEELAND, A. A, MULLENDERS, L. H. F

“…To study the relationship between transcription and strand-specific repair of UV-induced cyclobutane pyrimidine dimers, dimer removal was analyzed in a cell…”
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Development of DNA libraries specific for Chinese hamster chromosomes 3, 4, 9, 10, X, and Y by DOP-PCR by Xiao, Y, Slijepcevic, P, Arkesteijn, G, Darroudi, F, Natarajan, A T

“…In a previous study of ours, DNA libraries specific for Chinese hamster chromosomes 1, 2, 3, 5, 6, 7, and 8 were constructed by single laser flow sorting and…”
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Generation of mouse chromosome painting probes by DOP-PCR amplification of microdissected meiotic chromosomes by Xiao, Y, Darroudi, F, Kuipers, A G, de Jong, J H, de Boer, P, Natarajan, A T

“…We describe here the development of four sets of painting probes for mouse chromosomes 1 and 13, 2 and 8, 6 and 15, and X and Y by degenerate…”
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Chromosomal radiosensitivity of ataxia telangiectasia cells at different cell cycle stages by Natarajan, A T, Meyers, M

“…X-ray induced chromosomal aberrations in peripheral blood lymphocytes as well as in skin fibroblasts from ataxia telangiectasia patients, and from normal…”
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