Search Results - "Natalia S Pellegata"

Simultaneous magnetic resonance imaging of pH, perfusion and renal filtration using hyperpolarized 13C-labelled Z-OMPD by Grashei, Martin, Wodtke, Pascal, Skinner, Jason G., Sühnel, Sandra, Setzer, Nadine, Metzler, Thomas, Gulde, Sebastian, Park, Mihyun, Witt, Daniela, Mohr, Hermine, Hundshammer, Christian, Strittmatter, Nicole, Pellegata, Natalia S., Steiger, Katja, Schilling, Franz

“…pH alterations are a hallmark of many pathologies including cancer and kidney disease. Here, we introduce [1,5- 13 C 2 ]Z-OMPD as a hyperpolarized…”
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A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype by Occhi, Gianluca, Regazzo, Daniela, Trivellin, Giampaolo, Boaretto, Francesca, Ciato, Denis, Bobisse, Sara, Ferasin, Sergio, Cetani, Filomena, Pardi, Elena, Korbonits, Márta, Pellegata, Natalia S, Sidarovich, Viktoryia, Quattrone, Alessandro, Opocher, Giuseppe, Mantero, Franco, Scaroni, Carla

“…The CDKN1B gene encodes the cyclin-dependent kinase inhibitor p27(KIP1), an atypical tumor suppressor playing a key role in cell cycle regulation, cell…”
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Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas by Lee, Misu, Wiedemann, Tobias, Gross, Claudia, Leinhäuser, Ines, Roncaroli, Federico, Braren, Rickmer, Pellegata, Natalia S

“…Novel therapeutic approaches are needed to improve the postoperative management of residual nonfunctioning pituitary adenomas (NFPA), given their high relapse…”
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Editorial: New insights into multiple endocrine neoplasia type 1 by Barlier, Anne, Romanet, Pauline, Pellegata, Natalia S.

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MENX and MEN4 by Pellegata, Natalia S.

“…Multiple endocrine neoplasias are autosomal dominant disorders characterized by the occurrence of tumors in at least two endocrine glands. Two MEN syndromes…”
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p27kip1: a new multiple endocrine neoplasia gene? by Marinoni, Ilaria, Pellegata, Natalia S

“…Multiple endocrine neoplasias (MEN) are autosomal dominant disorders characterized by the occurrence of tumors in at least two endocrine glands. Two types of…”
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Angpt2/Tie2 autostimulatory loop controls tumorigenesis by Karabid, Ninelia Minaskan, Wiedemann, Tobias, Gulde, Sebastian, Mohr, Hermine, Segaran, Renu Chandra, Geppert, Julia, Rohm, Maria, Vitale, Giovanni, Gaudenzi, Germano, Dicitore, Alessandra, Ankerst, Donna Pauler, Chen, Yiyao, Braren, Rickmer, Kaissis, Georg, Schilling, Franz, Schillmaier, Mathias, Eisenhofer, Graeme, Herzig, Stephan, Roncaroli, Federico, Honegger, Jürgen B, Pellegata, Natalia S

“…Invasive nonfunctioning (NF) pituitary neuroendocrine tumors (PitNETs) are non‐resectable neoplasms associated with frequent relapses and significant…”
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Inceptor correlates with markers of prostate cancer progression and modulates insulin/IGF1 signaling and cancer cell migration by Wissmiller, Katharina, Bilekova, Sara, Franko, Andras, Lutz, Stefan Z., Katsburg, Miriam, Gulde, Sebastian, Pellegata, Natalia S., Stenzl, Arnulf, Heni, Martin, Berti, Lucia, Häring, Hans-Ulrich, Lickert, Heiko

“…The insulin/insulin-like growth factor 1 (IGF1) pathway is emerging as a crucial component of prostate cancer progression. Therefore, we investigated the role…”
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AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients by Daly, Adrian F, Rostomyan, Liliya, Betea, Daniela, Bonneville, Jean-François, Villa, Chiara, Pellegata, Natalia S, Waser, Beatrice, Reubi, Jean-Claude, Waeber Stephan, Catherine, Christ, Emanuel, Beckers, Albert

“…Acromegaly is a rare disease due to chronic excess growth hormone (GH) and IGF-1. Aryl hydrocarbon receptor interacting protein (AIP) mutations are associated…”
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Galectin-3, fibronectin-1, CITED-1, HBME1 and cytokeratin-19 immunohistochemistry is useful for the differential diagnosis of thyroid tumors by Prasad, Manju L, Pellegata, Natalia S, Huang, Ying, Nagaraja, Haikady N, Chapelle, Albert de la, Kloos, Richard T

“…The diagnosis of thyroid tumors is critical for clinical management; however, tumors with follicular architecture often present problems. We evaluated the…”
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Imaging pheochromocytoma in small animals: preclinical models to improve diagnosis and treatment by Mohr, Hermine, Foscarini, Alessia, Steiger, Katja, Ballke, Simone, Rischpler, Christoph, Schilling, Franz, Pellegata, Natalia S.

“…Pheochromocytomas (PCCs) and paragangliomas (PGLs), together referred to as PPGLs, are rare chromaffin cell-derived tumors. They require timely diagnosis as…”
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Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice by Ha, Elizabeth E., Quartuccia, Gabriella I., Ling, Ruifeng, Xue, Chenyi, Karikari, Rhoda A., Hernandez-Ono, Antonio, Hu, Krista Y., Matias, Caio V., Imam, Rami, Cui, Jian, Pellegata, Natalia S., Herzig, Stephan, Georgiadi, Anastasia, Soni, Rajesh K., Bauer, Robert C.

“…Multiple genome-wide association studies (GWAS) have identified SNPs in the 8q24 locus near TRIB1 that are significantly associated with plasma lipids and…”
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Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone by Miras, Alexander D, PhD, Mogford, Julianne T, BSc, Wright, John, Dr, Mendoza, Nigel N, FRCS, Xekouki, Paraskevi, MD, Lakhani, Amish, FRCR, Pellegata, Natalia S, PhD, Stratakis, Costantine A, Prof, Roncaroli, Federico, MB, Russell-Jones, David, Prof, MD

“…Because she was not taking fertility treatment or other drugs that might have caused the ovarian hyperstimulation she was referred to the endocrinology clinic…”
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Oncogenic features of the bone morphogenic protein 7 (BMP7) in pheochromocytoma by Leinhäuser, Ines, Richter, Andrea, Lee, Misu, Höfig, Ines, Anastasov, Nataša, Fend, Falko, Ercolino, Tonino, Mannelli, Massimo, Gimenez-Roqueplo, Anne-Paule, Robledo, Mercedes, de Krijger, Ronald, Beuschlein, Felix, Atkinson, Michael J, Pellegata, Natalia S

“…BMP7 is a growth factor playing pro- or anti-oncogenic roles in cancer in a cell type-dependent manner. We previously reported that the BMP7 gene is…”
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Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma by Molatore, Sara, Liyanarachchi, Sandya, Irmler, Martin, Perren, Aurel, Mannelli, Massimo, Ercolino, Tonino, Beuschlein, Felix, Jarzab, Barbara, Wloch, Jan, Ziaja, Jacek, Zoubaa, Saida, Neff, Frauke, Beckers, Johannes, Höfler, Heinz, Atkinson, Michael J., Pellegata, Natalia S., de la Chapelle, Albert

“…Pheochromocytomas are rare neoplasias of neural crest origin arising from chromaffin cells of the adrenal medulla and sympathetic ganglia (extra-adrenal…”
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Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases by Pellegata, Natalia S., Berriel Diaz, Mauricio, Rohm, Maria, Herzig, Stephan

“…Obesity is an established risk factor for several human cancers. Given the association between excess body weight and cancer, the increasing rates of obesity…”
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Papillary and Follicular Thyroid Carcinomas Show Distinctly Different Microarray Expression Profiles and Can Be Distinguished by a Minimum of Five Genes by ALDRED, Micheala A, YING HUANG, LIYANARACHCHI, Sandya, PELLEGATA, Natalia S, GIMM, Oliver, JHIANG, Sissy, DAVULURI, Ramana V, DE LA CHAPELLE, Albert, ENG, Charis

“…We have previously conducted independent microarray expression analyses of the two most common types of nonmedullary thyroid carcinoma, namely papillary…”
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p27 variant and corticotropinoma susceptibility: a genetic and in vitro study by Sekiya, Tomoko, Bronstein, Marcello D, Benfini, Katiuscia, Longuini, Viviane C, Jallad, Raquel S, Machado, Marcio C, Goncalves, Tatiana D, Osaki, Luciana H, Higashi, Leonardo, Viana-Jr, Jose, Kater, Claudio, Lee, Misu, Molatore, Sara, Francisco, Guilherme, Chammas, Roger, Naslavsky, Michel S, Schlesinger, David, Gama, Patricia, Duarte, Yeda A O, Lebrão, Maria Lucia, Zatz, Mayana, Meirelles, Osorio, Liberman, Bernardo, Fragoso, Maria Candida B V, Toledo, Sergio P A, Pellegata, Natalia S, Toledo, Rodrigo A

“…Abstract Germline mutations in p27kip1 are associated with increased susceptibility to multiple endocrine neoplasias (MEN) both in rats and humans; however,…”
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Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors by Molatore, Sara, Kiermaier, Eva, Jung, Christian B, Lee, Misu, Pulz, Elke, Höfler, Heinz, Atkinson, Michael J, Pellegata, Natalia S

“…p27Kip1 (p27) is an important negative regulator of the cell cycle and a putative tumor suppressor. The finding that a spontaneous germline frameshift mutation…”
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Animal models of MEN1 by Mohr, Hermine, Pellegata, Natalia S

“…Animal models of cancer have been instrumental in advancing our understanding of the biology of tumor initiation and progression, in studying gene function and…”
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