Search Results - "Nassour, Lauren"
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A Century of Fractionated Radiotherapy: How Mathematical Oncology Can Break the Rules
Published in International journal of molecular sciences (24-01-2022)“…Radiotherapy is involved in 50% of all cancer treatments and 40% of cancer cures. Most of these treatments are delivered in fractions of equal doses of…”
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STEM-18. A HIGH THROUGHPUT NEUROSPHERE BASED COLONY FORMATION ASSAY TO VALIDATE DRUG AND RADIATION EFFECTIVENESS IN PATIENT DERIVED XENOLINES
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract Glioblastoma (GBM) is a primary malignant brain tumor developed from normal astrocytes. GBM patients’ median survival is less than 2 years despite…”
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MODL-30. UTILIZING SERUM-FREE CO-CULTURE MODELS FOR IN-VITRO MODELING OF TUMOR-ASSOCIATED MACROPHAGES IN GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)“…Abstract BACKGROUND The GBM tumor microenvironment consists of various cancerous and non-cancerous cells that influence GBM growth, invasion, angiogenesis, and…”
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Exposure to Moderate Glycosuria Induces Virulence of Group B Streptococcus
Published in The Journal of infectious diseases (03-03-2021)“…Abstract To explore whether glycosuria induces virulence of uropathogens, in turn facilitating urinary tract infection (UTI), we exposed group B Streptococcus…”
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miRNA Signatures for a Human Proteotoxic Cardiac Disease
Published in Free radical biology & medicine (01-11-2020)Get full text
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TMOD-21. A NOVEL IN-VITRO METHOD TO MODEL MACROPHAGES IN GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (12-11-2021)“…Abstract BACKGROUND The GBM tumor microenvironment (TME) is comprised of a plethora of cancerous and non-cancerous cells that contribute to GBM growth,…”
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Abstract 4668: In-vitro modeling of tumor-associated macrophages in glioblastoma
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract BACKGROUND: The Glioblastoma (GBM) tumor microenvironment (TME) is comprised of a plethora of cancerous and non-cancerous cells that contribute to GBM…”
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Abstract 3568: Developing pediatric glioblastoma microtumors with a three-dimensional bioprinter
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background:Glioblastoma multiforme is one of the most devastating forms of brain cancer seen in children. Children diagnosed with high-grade gliomas…”
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Abstract 1102: Establishing the cytotoxic benefit of Tumor Treating Fields on radiation sensitive and acquired radiation resistant glioblastoma patient derived xenograft pairs
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: Glioblastoma (GBM) is the most common malignant primary brain tumor with very poor prognosis. The current standard of care for GBM…”
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TMOD-25. UTILIZING PRIMARY MACROPHAGES AS AN IMPROVED SERUM-FREE IN VITRO MODEL OF TUMOR-ASSOCIATED MACROPHAGES IN GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract BACKGROUND Tumor-associated macrophages (TAMs) account for up to 40% of tumor mass in glioblastoma and over 70% of the immune cells contained therein…”
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Abstract 1273: Glioblastoma brain tumor-initiating cells are protected from hypoxia when co-cultured with normal human astrocytes revealing a potential role for mitochondrial transfer via tunneling nanotubes
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: Glioblastoma (GBM) has a median survival of <2 years and generally recurs within 6 months of treatment due to the development of chemo-…”
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Abstract 3360: Myristoylated alanine-rich C-kinase substrate (MARCKS) as a target for pathological tunneling nanotubes in glioblastoma
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Glioblastoma (GBM) is a lethal brain malignancy with a median survival of <2 years due to relapse in 100% of cases. Tunneling nanotubes…”
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