Search Results - "Nassour, Hassan"
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Escherichia coli STb enterotoxin dislodges claudin-1 from epithelial tight junctions
Published in PloS one (19-11-2014)“…Enterotoxigenic Escherichia coli produce various heat-labile and heat-stable enterotoxins. STb is a low molecular weight heat-resistant toxin responsible for…”
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UVC-induced stress granules in mammalian cells
Published in PloS one (19-11-2014)“…Stress granules (SGs) are well characterized cytoplasmic RNA bodies that form under various stress conditions. We have observed that exposure of mammalian…”
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Towards Targeting the Urotensinergic System: Overview and Challenges
Published in Trends in pharmacological sciences (Regular ed.) (01-10-2019)“…The urotensinergic system, comprised of a G protein-coupled receptor (UT) and two endogenous ligands named urotensin II (UII) and urotensin II-related peptide…”
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Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors
Published in Cellular signalling (01-04-2024)“…Despite the observation of synergistic interactions between the urotensinergic and angiotensinergic systems, the interplay between the urotensin II receptor…”
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Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression
Published in Scientific reports (08-07-2016)“…APE1 is an essential DNA repair protein that also possesses the ability to regulate transcription. It has a unique cysteine residue C65, which maintains the…”
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Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands
Published in The Journal of biological chemistry (01-09-2021)“…Over the last decade, the urotensinergic system, composed of one G protein-coupled receptor and two endogenous ligands, has garnered significant attention as a…”
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Spt5 Phosphorylation and the Rtf1 Plus3 Domain Promote Rtf1 Function through Distinct Mechanisms
Published in Molecular and cellular biology (14-07-2020)“…Rtf1 is a conserved RNA polymerase II (RNAPII) elongation factor that promotes cotranscriptional histone modification, RNAPII transcript elongation, and mRNA…”
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Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2
Published in Scientific reports (07-11-2016)“…Fascin 1 (FSCN1) is a cytoskeleton-associated protein recognized to function primarily in the regulation of cytoskeleton structure and formation of plasma…”
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New directions for urotensin II receptor ligands
Published in Peptide science (Hoboken, N.J.) (01-01-2019)“…The urotensinergic system, formed by a G protein‐coupled receptor (GPCR) termed UT and two endogenous peptide ligands Urotensin II (UII,…”
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