Search Results - "Nassir, Molhm"

A Stereodivergent Approach to the Synthesis of gem‐Diborylcyclopropanes by Hanania, Nicole, Nassir, Molhm, Eghbarieh, Nadim, Masarwa, Ahmad

“…We report a designed stereodivergent strategy for the synthesis of gem‐diborylcyclopropanes. The reaction provides a highly modular approach to prepare…”
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Enantioselective Crystallization of Chiral Inorganic Crystals of ϵ‐Zn(OH)2 with Amino Acids by Otis, Gil, Nassir, Molhm, Zutta, Michael, Saady, Abed, Ruthstein, Sharon, Mastai, Yitzhak

“…Many inorganic materials can form crystals, but little is known about their enantioselective crystallization. Herein, we report on the enantioselective…”
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Chiral Porous Carbon Surfaces for Enantiospecific Synthesis by Aloni, Sapir Shekef, Nassir, Molhm, Mastai, Yitzhak

“…Chiral surfaces, developed in the last decade, serve as media for enantioselective chemical reactions. Until today, they have been based mostly on developments…”
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Adenine-(methoxy)-ethoxy-P α,α -dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes by Nassir, Molhm, Mirza, Salahuddin, Arad, Uri, Lee, Sangyong, Rafehi, Muhammad, Yaw Attah, Isaac, Renn, Christian, Zimmermann, Herbert, Pelletier, Julie, Sévigny, Jean, Müller, Christa E, Fischer, Bilha

“…Nucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) inhibitors have been suggested as a potential treatment for calcium pyrophosphate dihydrate (CPPD)…”
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Enantioselective Crystallization of Chiral Inorganic Crystals of ϵ‐Zn(OH)2 with Amino Acids by Otis, Gil, Nassir, Molhm, Zutta, Michael, Saady, Abed, Ruthstein, Sharon, Mastai, Yitzhak

“…Many inorganic materials can form crystals, but little is known about their enantioselective crystallization. Herein, we report on the enantioselective…”
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Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes by Nassir, Molhm, Arad, Uri, Lee, Sang-Yong, Journo, Shani, Mirza, Salahuddin, Renn, Christian, Zimmermann, Herbert, Pelletier, Julie, Sévigny, Jean, Müller, Christa E., Fischer, Bilha

“…Overproduction of extracellular diphosphate due to hydrolysis of ATP by NPP1 leads to pathological calcium diphosphate (pyrophosphate) dihydrate deposition…”
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Correction to: Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes by Nassir, Molhm, Arad, Uri, Lee, Sang-Yong, Journo, Shani, Renn, Salahuddin Mirza Christian, Zimmermann, Herbert, Pelletier, Julie, Sévigny, Jean, Müller, Christa E., Fischer, Bilha

“…The original version of the article unfortunately contained an error…”
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Hydrolytic (in)stability of phosphate isosteres by Nassir, Molhm, Isaak, Avinoam, Fischer, Bilha

“…For decades enzymatic hydrolysis of nucleotides, a cornerstone of life, was studied extensively along with the chemical hydrolytic reaction. The metabolic…”
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Stereoselective Diels–Alder Reactions of gem-Diborylalkenes: Toward the Synthesis of gem-Diboron-Based Polymers by Eghbarieh, Nadim, Hanania, Nicole, Zamir, Alon, Nassir, Molhm, Stein, Tamar, Masarwa, Ahmad

“…Although gem-diborylalkenes are known to be among the most valuable reagents in modern organic synthesis, providing a rapid access to a wide array of…”
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Ultrasonic assisted synthesis of styrylpyridinium dyes: Optical properties and DFT calculations by Saady, Abed, Sudhakar, Pagidi, Nassir, Molhm, Gedanken, Aharon

“…[Display omitted] •High yield synthesis of styrylpyridinium dyes using ultrasonic irradiation.•Mild reaction conditions and very short reaction time (15 min)…”
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Sonochemically modified ovalbumin enhances enantioenrichment of some amino acids by Mutalikdesai, Amruta, Nassir, Molhm, Saady, Abed, Hassner, Alfred, Gedanken, Aharon

“…[Display omitted] •Sonochemical preparation of Ovalbumin microspheres.•Chiral microspheres interact selectively with one enantiomer of the racemate.•For…”
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Stereocontrolled Radical Thiophosphorylation by Nassir, Molhm, Ociepa, Michał, Zhang, Hai-Jun, Grant, Lauren N., Simmons, Bryan J., Oderinde, Martins S., Kawamata, Yu, Cauley, Anthony N., Schmidt, Michael A., Eastgate, Martin D., Baran, Phil S.

“…The first practical, fully stereoselective P­(V)-radical hydrophosphorylation is presented herein by using simple, limonene-derived reagent systems. A set of…”
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An electroaffinity labelling platform for chemoproteomic-based target identification by Kawamata, Yu, Ryu, Keun Ah, Hermann, Gary N., Sandahl, Alexander, Vantourout, Julien C., Olow, Aleksandra K., Adams, La-Tonya A., Rivera-Chao, Eva, Roberts, Lee R., Gnaim, Samer, Nassir, Molhm, Oslund, Rob C., Fadeyi, Olugbeminiyi O., Baran, Phil S.

“…Target identification involves deconvoluting the protein target of a pharmacologically active, small-molecule ligand, a process that is critical for early drug…”
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Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold by Nassir, Molhm, Pelletier, Julie, Arad, Uri, Arguin, Guillaume, Khazanov, Netaly, Gendron, Fernand-Pierre, Sévigny, Jean, Senderowitz, Hanoch, Fischer, Bilha

“…Overexpression of ecto-nucleotide pyrophosphatase-1 (NPP1) is associated with diseases such as calcium pyrophosphate dihydrate deposition disease, calcific…”
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Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates by Zhang, Hai-Jun, Ociepa, Michał, Nassir, Molhm, Zheng, Bin, Lewicki, Sarah A., Salmaso, Veronica, Baburi, Helay, Nagel, Jessica, Mirza, Salahuddin, Bueschbell, Beatriz, Al-Hroub, Haneen, Perzanowska, Olga, Lin, Ziqin, Schmidt, Michael A., Eastgate, Martin D., Jacobson, Kenneth A., Müller, Christa E., Kowalska, Joanna, Jemielity, Jacek, Baran, Phil S.

“…Nucleoside diphosphates and triphosphates impact nearly every aspect of biochemistry; however, the use of such compounds as tools or medicinal leads for…”
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Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by the Cu(II)–Prion Peptide Complex by Pariente Cohen, Natalie, Lo Presti, Eliana, Dell’Acqua, Simone, Jantz, Thomas, Shimon, Linda J. W, Levy, Naomi, Nassir, Molhm, Elbaz, Lior, Casella, Luigi, Fischer, Bilha

“…Recently, we reported on a series of aminomethylene-phosphonate (AMP) analogues, bearing one or two heterocyclic groups on the aminomethylene moiety, as…”
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Correction to Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by Cu(II)–Prion Peptide Complex by Pariente Cohen, Natalie, Lo Presti, Eliana, Dell’Acqua, Simone, Jantz, Thomas, Shimon, Linda J. W, Levi Hevroni, Bosmat, Levy, Naomi, Nassir, Molhm, Elbaz, Lior, Casella, Luigi, Fischer, Bilha

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A New Approach to Chiral Enrichment by Exposure of Racemates of Amino Acids to Sonochemically‐Prepared BSA Microspheres by Kumar, Vijay Bhooshan, Steinberg, Yael, Porat, Ze'ev, Nassir, Molhm, Saady, Abed, Hassner, Alfred, Gedanken, Aharon

“…This preliminary study describes a one‐step sonochemical formation of Bovine Serum Albumin (BSA) microspheres and their chiral interaction with several amino…”
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