Search Results - "Nasser, Suzanne A."

Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms by Slika, Hasan, Mansour, Hadi, Wehbe, Nadine, Nasser, Suzanne A., Iratni, Rabah, Nasrallah, Gheyath, Shaito, Abdullah, Ghaddar, Tarek, Kobeissy, Firas, Eid, Ali H.

“…Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and…”
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Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders by Dakroub, Ali, A Nasser, Suzanne, Younis, Nour, Bhagani, Humna, Al-Dhaheri, Yusra, Pintus, Gianfranco, Eid, Assaad A, El-Yazbi, Ahmed F, Eid, Ali H

“…Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell…”
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Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells by Badran, Adnan, Nasser, Suzanne A, Mesmar, Joelle, El-Yazbi, Ahmed F, Bitto, Alessandra, Fardoun, Manal M, Baydoun, Elias, Eid, Ali H

“…Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling…”
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Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay by Mansour, Hadi, Slika, Hasan, Nasser, Suzanne A., Pintus, Gianfranco, Khachab, Maha, Sahebkar, Amirhossein, Eid, Ali H.

“…Cardiovascular disease (CVD) remains the leading cause of global morbidity and mortality. Extensive efforts have been invested to explicate mechanisms…”
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The Mitochondria: A Target of Polyphenols in the Treatment of Diabetic Cardiomyopathy by Bhagani, Humna, Nasser, Suzanne A, Dakroub, Ali, El-Yazbi, Ahmed F, Eid, Assaad A, Kobeissy, Firas, Pintus, Gianfranco, Eid, Ali H

“…Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The…”
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Inflammatory Basis of Atherosclerosis: Modulation by Sex Hormones by Nasser, Suzanne A, Afify, Elham A, Kobeissy, Firas, Hamam, Bassam, Eid, Ali H, El-Mas, Mahmoud M

“…Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory…”
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The Role of Epac in Cancer Progression by Wehbe, Nadine, Slika, Hasan, Mesmar, Joelle, Nasser, Suzanne A, Pintus, Gianfranco, Baydoun, Serine, Badran, Adnan, Kobeissy, Firas, Eid, Ali H, Baydoun, Elias

“…Cancer continues to be a prime contributor to global mortality. Despite tremendous research efforts and major advances in cancer therapy, much remains to be…”
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Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells by AlKahlout, Amal, Fardoun, Manal, Mesmar, Joelle, Abdallah, Rola, Badran, Adnan, Nasser, Suzanne A, Baydoun, Serine, Kobeissy, Firas, Shaito, Abdullah, Iratni, Rabah, Muhammad, Khalid, Baydoun, Elias, Eid, Ali H

“…Breast cancer is the leading cause of cancer-related deaths among women. Among breast cancer types, triple negative breast cancer (TNBC) is the most…”
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Sex differences in pain and opioid mediated antinociception: Modulatory role of gonadal hormones by Nasser, Suzanne A., Afify, Elham A.

“…Sex-related differences in pain and opioids has been the focus of many researches. It is demonstrated that women experience greater clinical pain, lower pain…”
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Inflammation and hypertension: Underlying mechanisms and emerging understandings by Aboukhater, Diana, Morad, Bassel, Nasrallah, Nadim, Nasser, Suzanne A., Sahebkar, Amirhossein, Kobeissy, Firas, Boudaka, Ammar, Eid, Ali H.

“…Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood…”
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Estrogen and Bisphenol A in Hypertension by Wehbe, Zena, Nasser, Suzanne A., El-Yazbi, Ahmed, Nasreddine, Salam, Eid, Ali H.

“…Purpose of Review Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with…”
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Epac as a tractable therapeutic target by Slika, Hasan, Mansour, Hadi, Nasser, Suzanne A., Shaito, Abdullah, Kobeissy, Firas, Orekhov, Alexander N., Pintus, Gianfranco, Eid, Ali H.

“…In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein…”
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Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases by Dakroub, Ali, Nasser, Suzanne A., Kobeissy, Firas, Yassine, Hadi M., Orekhov, Alexander, Sharifi‐Rad, Javad, Iratni, Rabah, El‐Yazbi, Ahmed F., Eid, Ali H.

“…Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of…”
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MicroRNAs in Cardiac Hypertrophy by Wehbe, Nadine, Nasser, Suzanne Awani, Pintus, Gianfranco, Badran, Adnan, Eid, Ali H, Baydoun, Elias

“…Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress…”
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GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells by Fardoun, Manal, Nasser, Suzanne A, El-Yazbi, Ahmed F, Eid, Ali H

“…Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen…”
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Endothelin ETA receptor antagonism in cardiovascular disease by Nasser, Suzanne A., El-Mas, Mahmoud M.

“…Since the discovery of the endothelin system in 1988, it has been implicated in numerous physiological and pathological phenomena. In the cardiovascular…”
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Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction by Fardoun, Manal M., Issa, Khodr, Maaliki, Dina, Nasser, Suzanne A., Baydoun, Elias, Eid, Ali H.

“…Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth…”
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Mechanisms underlying the effects of caloric restriction on hypertension by Al Attar, Ahmad A., Fahed, Gracia I., Hoballah, Malak M., Pedersen, Shona, El-Yazbi, Ahmed F., Nasser, Suzanne A., Bitto, Alessandra, Orekhov, Alexander N., Eid, Ali H.

“…[Display omitted] Hypertension is a major risk factor for cardiovascular disease (CVD) as well as a major contributor to all-cause mortality and disability…”
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C‐peptide in diabetes: A player in a dual hormone disorder? by Dakroub, Ali, Dbouk, Ali, Asfour, Aref, Nasser, Suzanne A., El‐Yazbi, Ahmed F., Sahebkar, Amirhossein, Eid, Assaad A., Iratni, Rabah, Eid, Ali H.

“…C‐peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C‐peptide serves an anti‐inflammatory…”
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The involvement of KATP channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats by Afify, Elham A., Khedr, Mohamed M., Omar, Amal G., Nasser, Suzanne A.

“…This study investigated the role of KATP channels in morphine‐induced antinociception and hepatic oxidative stress in acute and inflammatory pain. The KATP…”
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