Search Results - "Nasser, Suzanne"
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1
MicroRNAs in Cardiac Hypertrophy
Published in International journal of molecular sciences (23-09-2019)“…Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress…”
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2
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
Published in Biomedicine & pharmacotherapy (01-02-2022)“…Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and…”
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3
Sex differences in pain and opioid mediated antinociception: Modulatory role of gonadal hormones
Published in Life sciences (1973) (15-11-2019)“…Sex-related differences in pain and opioids has been the focus of many researches. It is demonstrated that women experience greater clinical pain, lower pain…”
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4
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
Published in Cells (Basel, Switzerland) (09-11-2020)“…Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell…”
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5
Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells
Published in International journal of molecular sciences (20-11-2020)“…Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling…”
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6
Inflammation and hypertension: Underlying mechanisms and emerging understandings
Published in Journal of cellular physiology (01-06-2023)“…Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood…”
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7
Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay
Published in Pharmacological research (01-11-2024)“…Cardiovascular disease (CVD) remains the leading cause of global morbidity and mortality. Extensive efforts have been invested to explicate mechanisms…”
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8
Estrogen and Bisphenol A in Hypertension
Published in Current hypertension reports (01-03-2020)“…Purpose of Review Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with…”
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9
Epac as a tractable therapeutic target
Published in European journal of pharmacology (15-04-2023)“…In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein…”
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10
Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases
Published in Journal of cellular physiology (01-09-2021)“…Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of…”
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11
The Mitochondria: A Target of Polyphenols in the Treatment of Diabetic Cardiomyopathy
Published in International journal of molecular sciences (14-07-2020)“…Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The…”
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12
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
Published in Journal of cardiovascular pharmacology (01-12-2023)“…Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen…”
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13
Inflammatory Basis of Atherosclerosis: Modulation by Sex Hormones
Published in Current pharmaceutical design (01-01-2021)“…Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory…”
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14
The Role of Epac in Cancer Progression
Published in International journal of molecular sciences (05-09-2020)“…Cancer continues to be a prime contributor to global mortality. Despite tremendous research efforts and major advances in cancer therapy, much remains to be…”
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15
Endothelin ETA receptor antagonism in cardiovascular disease
Published in European journal of pharmacology (15-08-2014)“…Since the discovery of the endothelin system in 1988, it has been implicated in numerous physiological and pathological phenomena. In the cardiovascular…”
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16
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
Published in Vascular pharmacology (01-08-2020)“…Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth…”
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Mechanisms underlying the effects of caloric restriction on hypertension
Published in Biochemical pharmacology (01-06-2022)“…[Display omitted] Hypertension is a major risk factor for cardiovascular disease (CVD) as well as a major contributor to all-cause mortality and disability…”
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18
C‐peptide in diabetes: A player in a dual hormone disorder?
Published in Journal of cellular physiology (01-05-2024)“…C‐peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C‐peptide serves an anti‐inflammatory…”
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19
Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells
Published in Frontiers in oncology (30-06-2022)“…Breast cancer is the leading cause of cancer-related deaths among women. Among breast cancer types, triple negative breast cancer (TNBC) is the most…”
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20
The involvement of KATP channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats
Published in Fundamental & clinical pharmacology (01-12-2013)“…This study investigated the role of KATP channels in morphine‐induced antinociception and hepatic oxidative stress in acute and inflammatory pain. The KATP…”
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