Search Results - "Nassar, Munir N."

Influence of Formaldehyde Impurity in Polysorbate 80 and PEG-300 on the Stability of a Parenteral Formulation of BMS-204352: Identification and Control of the Degradation Product by Nassar, Munir N., Nesarikar, Vishwas N., Lozano, Ruben, Parker, William L., Huang, Yande, Palaniswamy, Venkatapuram, Xu, Weiwei, Khaselev, Nona

“…The purpose of this study was to identify a degradation product formed in the clinical parenteral formulation of BMS-204352, investigate the role of excipients…”
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Ethyl methanesulphonate in a parenteral formulation of BMS-214662 mesylate, a selective farnesyltransferase inhibitor: Formation and rate of hydrolysis by Nassar, Munir N., Cucolo, Michael, Miller, Scott A.

“…The objectives of the present study were to investigate the formation and rate of hydrolysis of ethyl methanesulphonate (EMS) in BMS-214662 mesylate drug…”
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Effect of Cations and Anions on Glass Transition Temperatures in Excipient Solutions by Nesarikar, Vishwas V., Nassar, Munir N.

“…The purpose of this study was to investigate the effects of cations and anions of various electrolytes on the glass transition temperature (Tg') of frozen…”
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Impurities in a Lyophilized Formulation of BMS-204352: Identification and Role of Sanitizing Agents by Nassar, Munir N., Nesarikar, Vishwas V., Khaselev, Nona, Lozano, Ruben

“…The purpose of this study was to identify two impurities in the parenteral lyophilized formulation of BMS-204352, investigate the role of sanitizing agents as…”
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Degradation of a lyophilized formulation of BMS-204352 : Identification of degradants and role of elastomeric closures by NASSAR, Munir N, NESARIKAR, Vishwas V, LOZANO, Ruben, YANDE HUANG, PALANISWAMY, Venkatapuram

“…The purpose of this study was to identify two degradation products formed in the parenteral lyophilized formulation of BMS-204352, investigate the possible…”
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Ethyl methanesulphonate in a parenteral formulation of BMS-214662 mesylate, a selective farnesyltransferase inhibitor: Formation and rate of hydrolysis by Nassar, Munir N., Cucolo, Michael, Miller, Scott A.

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Implications of trace levels of redox-active metals in drug-product formulation by Sadineni, Vikram, Chandrasekharan, Sangita, Nassar, Munir N

“…Results generated during the development of commercial formulation of the model monoclonal antibody (mAb), Biologic A, have indicated the formation of…”
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Degradation of a Lyophilized Formulation of BMS-204352: Identification of Degradants and Role of Elastomeric Closures by Nassar, Munir N., Nesarikar, Vishwas V., Lozano, Ruben, Huang, Yande, Palaniswamy, Venkatapuram

“…The purpose of this study was to identify two degradation products formed in the parenteral lyophilized formulation of BMS-204352, investigate the possible…”
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Effects of structural variations on the rates of enzymatic and nonenzymatic hydrolysis of carbonate and carbamate esters by Nassar, M N, Agha, B J, Digenis, G A

“…The effect of structural variations on the rates of elastase-catalyzed hydrolysis of model carbonate and carbamate esters was studied using HPLC. It is shown…”
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Stability of batanopride hydrochloride in aqueous solutions by Nassar, M N, House, C A, Agharkar, S N

“…The degradation of batanopride hydrochloride, an investigational antiemetic drug, was studied in aqueous buffer solutions (pH 2-10; ionic strength, 0.5; 56…”
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