Search Results - "Nassal, M"

Emerging therapeutic targets for cardiac hypertrophy by Winkle, Alexander J, Nassal, Drew M, Shaheen, Rebecca, Thomas, Evelyn, Mohta, Shivangi, Gratz, Daniel, Weinberg, Seth H, Hund, Thomas J

“…Cardiac hypertrophy is associated with adverse outcomes across cardiovascular disease states. Despite strides over the last three decades in identifying…”
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KChIP2 is a core transcriptional regulator of cardiac excitability by Nassal, Drew M, Wan, Xiaoping, Liu, Haiyan, Maleski, Danielle, Ramirez-Navarro, Angelina, Moravec, Christine S, Ficker, Eckhard, Laurita, Kenneth R, Deschênes, Isabelle

“…Arrhythmogenesis from aberrant electrical remodeling is a primary cause of death among patients with heart disease. Amongst a multitude of remodeling events,…”
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Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role by Nassal, Drew M, Wan, Xiaoping, Liu, Haiyan, Deschênes, Isabelle

“…Cardiac ion channels and their respective accessory subunits are critical in maintaining proper electrical activity of the heart. Studies have indicated that…”
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KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity by Nassal, Drew M, Wan, Xiaoping, Liu, Haiyan, Laurita, Kenneth R, Deschênes, Isabelle

“…Pathologic electrical remodeling and attenuated cardiac contractility are featured characteristics of heart failure. Coinciding with these remodeling events is…”
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Novel application of thoracic impedance to characterize ventilations during cardiopulmonary resuscitation in the pragmatic airway resuscitation trial by Nassal, Michelle M.J., Jaureguibeitia, Xabier, Aramendi, Elisabete, Irusta, Unai, Panchal, Ashish R., Wang, Henry E., Idris, Ahamed

“…Significant challenges exist in measuring ventilation quality during out-of-hospital cardiopulmonary arrest (OHCA) outcomes. Since ventilation is associated…”
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Spectrin-Based Regulation of Cardiac Fibroblast Cell-Cell Communication by Nassal, Drew M, Shaheen, Rebecca, Patel, Nehal J, Yu, Jane, Leahy, Nick, Bibidakis, Dimitra, Parinandi, Narasimham L, Hund, Thomas J

“…Cardiac fibroblasts (CFs) maintain the fibrous extracellular matrix (ECM) that supports proper cardiac function. Cardiac injury induces a transition in the…”
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Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na + channel function by Nassal, Michelle M J, Wan, Xiaoping, Dale, Zack, Deschênes, Isabelle, Wilson, Lance D, Piktel, Joseph S

“…Acute cardiac ischemia induces conduction velocity (CV) slowing and conduction block, promoting reentrant arrhythmias leading to sudden cardiac arrest…”
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Atrial SERCA2a Overexpression Has No Affect on Cardiac Alternans but Promotes Arrhythmogenic SR Ca2+ Triggers by Nassal, Michelle M J, Wan, Xiaoping, Laurita, Kenneth R, Cutler, Michael J

“…Atrial fibrillation (AF) is the most common arrhythmia in humans, yet; treatment has remained sub-optimal due to poor understanding of the underlying…”
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Longitudinal Changes in Emergency Medical Services Advanced Airway Management by Wang, Henry E, Yu, Mengda Ivy, Crowe, Remle P, Nassal, Michelle M J, Gage, Christopher, Hyer, J Madison, Powell, Jonathan, Ulintz, Alexander, Sharkey-Toppen, Travis, Wei, Lai, Moeller, Kim, Panchal, Ashish R

“…Identifying longitudinal changes in advanced airway management by emergency medical services (EMS) is crucial for understanding practice patterns and…”
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The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly by NASSAL, M

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Peering into the Molecular Machinery for Regulation of Cav1.2 Channel Clusters by Nassal, Drew M., Hund, Thomas J.

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Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress by NASSAL, MICHELLE M. J., WERDICH, ANDREAS A., WAN, XIAOPING, HOSHI, MALCOLM, DESCHÊNES, ISABELLE, ROSENBAUM, DAVID S., DONAHUE, J. KEVIN

“…Cx43‐S368 Phosphorylation Controls Conduction During Stress Connexin43 (Cx43) phosphorylation alters gap junction localization and function. In particular,…”
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Hepatitis B virus morphogenesis by Nassal, M

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Hepatitis B virus replication--an update by Nassal, M, Schaller, H

“…Hepatitis B virus (HBV), the causative agent of type B hepatitis in humans, is the prototypic member of the hepadnaviridae, a family of small enveloped…”
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Hepatitis B Virus (HBV) Virion and Covalently Closed Circular DNA Formation in Primary Tupaia Hepatocytes and Human Hepatoma Cell Lines upon HBV Genome Transduction with Replication-Defective Adenovirus Vectors by Ren, S, Nassal, M

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A bulged region of the hepatitis B virus RNA encapsidation signal contains the replication origin for discontinuous first-strand DNA synthesis by Nassal, M, Rieger, A

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792 HBV-HCV COINFECTION: A NOVEL MODEL SYSTEM REVEALS INSIGHTS INTO IMMUNOLOGICAL MECHANISMS OF VIRAL INTERFERENCE by Lass, C, Präg, C, Grimm, D, Gouttenoire, J, Lohmann, V, Köck, J, Nassal, M, Blum, H.E, Bartenschlager, R, Moradpour, D, Thimme, R, Brass, V

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638 IFN-α TREATMENT OF HEPATITIS B VIRUS (HBV)-INFECTED PRIMARY HUMAN HEPATOCYTES LEADS TO A SPECIFIC REDUCTION OF HBV MRNA LEVELS by Zhang, J, Köck, J, Blum, H.E, Nassal, M, Rasenack, J, Baumert, T, Thoma, C

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Emerging therapeutic targets for cardiac arrhythmias: role of STAT3 in regulating cardiac fibroblast function by Patel, Nehal J, Nassal, Drew M, Gratz, Daniel, Hund, Thomas J

“…: Cardiac fibrosis contributes to the development of cardiovascular disease (CVD) and arrhythmia. Cardiac fibroblasts (CFs) are collagen-producing cells that…”
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A Short N-Proximal Region in the Large Envelope Protein Harbors a Determinant That Contributes to the Species Specificity of Human Hepatitis B Virus by Chouteau, P, Le Seyec, J, Cannie, I, Nassal, M, Guguen-Guillouzo, C, Gripon, P

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