Search Results - "Nass, Ralf"
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Intensive, telemedicine-based, self-management program for rural, underserved patients with diabetes mellitus: Re-entry of retired endocrinologists into practice
Published in Journal of telemedicine and telecare (01-02-2023)“…Endocrinology workforce data demonstrate a substantial gap in the number of practicing endocrinologists, a phenomenon particularly affecting patients with…”
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Growth Hormone Axis and Aging
Published in Endocrinology and metabolism clinics of North America (01-06-2013)“…Growth hormone (GH) and/or ghrelin mimetics represent potential treatment and/or prevention options for musculoskeletal impairment associated with aging. Use…”
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The Use of a Smart Bolus Calculator Informed by Real-time Insulin Sensitivity Assessments Reduces Postprandial Hypoglycemia Following an Aerobic Exercise Session in Individuals With Type 1 Diabetes
Published in Diabetes care (01-04-2020)“…Insulin dosing in type 1 diabetes (T1D) is oftentimes complicated by fluctuating insulin requirements driven by metabolic and psychobehavioral factors…”
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Age-Dependent Decline in Acyl-Ghrelin Concentrations and Reduced Association of Acyl-Ghrelin and Growth Hormone in Healthy Older Adults
Published in The journal of clinical endocrinology and metabolism (01-02-2014)“…Background: Acyl-ghrelin is thought to have both orexigenic effects and to stimulate GH release. A possible cause of the anorexia of aging is an age-dependent…”
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Decrease of Serum IGF-I following Transsphenoidal Pituitary Surgery for Acromegaly
Published in Clinical chemistry (Baltimore, Md.) (01-02-2017)“…In the immediate postoperative period following resection of growth hormone (GH)-secreting pituitary tumors, serum concentrations of GH have limited ability to…”
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Ghrelin and growth hormone: Story in reverse
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2010)Get full text
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The ghrelin axis in disease: Potential therapeutic indications
Published in Molecular and cellular endocrinology (20-06-2011)“…Ghrelin, the natural ligand for the growth hormone (GH)-secretagogue receptor (GHS-R), is produced predominantly in the stomach. It is present in the…”
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Recent Exposure to Hypoglycemia Increases Glucose Variability Following a Hyper/Hypoglycemic Metabolic Challenge in T1D
Published in Journal of diabetes science and technology (01-03-2018)“…Aims: In type 1 diabetes (T1D), repeated hypoglycemic episodes may reduce hormonal defenses and increase the risk for severe hypoglycemia. In this work, we…”
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Evidence for Acyl-Ghrelin Modulation of Growth Hormone Release in the Fed State
Published in The journal of clinical endocrinology and metabolism (01-05-2008)“…Context: The timing and frequency of GH secretory episodes is regulated by GHRH and somatostatin. This study provides evidence for amplification of these GH…”
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ECTOPIC THYROID TISSUE MASQUERADING AS A FUNCTIONAL CAROTID BODY PARAGANGLIOMA
Published in AACE clinical case reports (01-07-2020)“…Ectopic thyroid tissue (ETT) is a rare entity resulting from thyroid gland dysembryogenesis. We present a case of ETT confirmed by histopathology that was…”
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Intrarenal Ghrelin Infusion Stimulates Distal Nephron-Dependent Sodium Reabsorption in Normal Rats
Published in Hypertension (Dallas, Tex. 1979) (01-03-2011)“…Ghrelin is a 28-amino acid peptide hormone that exerts powerful orexigenic effects. Ghrelin receptor expression has been reported in the kidney, but the role…”
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The ghrelin O-acyltransferase–ghrelin system: a novel regulator of glucose metabolism
Published in Current opinion in endocrinology, diabetes, and obesity (01-02-2011)“…Ghrelin, an orexigenic hormone secreted from the stomach, exists in the circulation in two isoforms: des-acyl and acyl ghrelin. Acylation by the enzyme ghrelin…”
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Growth Hormone Supplementation in the Elderly
Published in Endocrinology and metabolism clinics of North America (01-03-2007)“…The imminent rapid increase in numbers of aging adults will significantly impact society and the health system in the coming years. The imperative is to allow…”
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Growth Hormone Axis and Aging: Aging and Endocrinology
Published in Endocrinology and metabolism clinics of North America (2013)Get full text
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Evaluation of a Web-Based Simulation Tool for Self-Management Support in Type 1 Diabetes: A Pilot Study
Published in IEEE journal of biomedical and health informatics (01-01-2023)“…Objective: To develop and evaluate a novel Web-based Simulation Tool (WST) that brings simulation technologies to people with Type 1 Diabetes (T1D), enabling…”
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Adaptive Biobehavioral Control: A Pilot Analysis of Human-Machine Coadaptation in Type 1 Diabetes
Published in Diabetes technology & therapeutics (01-09-2024)“…While it is well recognized that an automated insulin delivery (AID) algorithm should adapt to changes in physiology, it is less understood that the individual…”
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783-P: When Automated Insulin Delivery Technology Meets Behavior: A Pilot Exploration of Human-Machine Coadaptation in Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Background: Automated Insulin Delivery (AID) devices in type 1 diabetes (T1D) are becoming standard of care, and the need for adaptive AID systems is now well…”
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97-LB: Bringing Simulation Technologies to People with T1D: A Pilot Study
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Background: Researchers have extensively used metabolic simulators as a fast, inexpensive, and safe way of testing novel treatment strategies. This work aims…”
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Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults : A Randomized Trial
Published in Annals of internal medicine (04-11-2008)“…Growth hormone secretion and muscle mass decline from midpuberty throughout life, culminating in sarcopenia, frailty, decreased function, and loss of…”
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Rejuvenation in Older Adults Receiving Oral Ghrelin
Published in Annals of internal medicine (05-05-2009)Get full text
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