Search Results - "Nasrollahi, Samila"
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Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matrices
Published in Scientific reports (05-01-2016)“…Epithelial cells disengage from their clusters and become motile by undergoing epithelial-to-mesenchymal transition (EMT), an essential process for both…”
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Past matrix stiffness primes epithelial cells and regulates their future collective migration through a mechanical memory
Published in Biomaterials (01-11-2017)“…During morphogenesis and cancer metastasis, grouped cells migrate through tissues of dissimilar stiffness. Although the influence of matrix stiffness on…”
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Nanoscale Matrix Topography Influences Microscale Cell Motility through Adhesions, Actin Organization, and Cell Shape
Published in ACS biomaterials science & engineering (13-11-2017)“…Mammalian cells are exposed to complex microenvironments of varying micro- and nanoscale structural features. These multiscale extracellular cues dictate…”
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Aqueous biphasic cancer cell migration assay enables robust, high-throughput screening of anti-cancer compounds
Published in Biotechnology journal (01-03-2014)“…Migration of tumor cells is a fundamental event implicated in metastatic progression of cancer. Therapeutic compounds with the ability to inhibit the motility…”
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Phytochemicals potently inhibit migration of metastatic breast cancer cells
Published in Integrative biology (Cambridge) (01-07-2015)“…Cell migration is a major process that drives metastatic progression of cancers, the major cause of cancer death. Existing chemotherapeutic drugs have limited…”
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Mechanobiology of Epithelial Clusters in ECMs of Diverse Mechanical Properties
Published 01-01-2017“…Cell clusters reside in complex extracellular matrices (ECMs) of varying mechanical properties. Epithelial cells sense and translate the mechanical cues…”
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Dissertation -
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Phytochemicals potently inhibit migration of metastatic breast cancer cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ib00121h
Published 06-07-2015“…Cell migration is a major process that drives metastatic progression of cancers, the major cause of cancer death. Existing chemotherapeutic drugs have limited…”
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Journal Article -
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High Throughput Screening of Natural Phenolic Compounds Against Migration of Metastatic Triple-Negative Breast Cancer (TNBC) Cells
Published 14-09-2013“…In this report, we hypothesize that natural phenolic compounds may present a new class of chemotherapeutics against migration of metastatic triple-negative…”
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Journal Article