Search Results - "Nasoohi, Sanaz"

Tissue Plasminogen Activator Promotes TXNIP-NLRP3 Inflammasome Activation after Hyperglycemic Stroke in Mice by Ismael, Saifudeen, Nasoohi, Sanaz, Yoo, Arum, Ahmed, Heba A., Ishrat, Tauheed

“…Hyperglycemia has been shown to counterbalance the beneficial effects of tissue plasminogen activator (tPA) and increase the risk of intracerebral hemorrhage…”
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Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer's Disease Brain by Li, Lexiao, Ismael, Saifudeen, Nasoohi, Sanaz, Sakata, Kazuko, Liao, Francesca-Fang, McDonald, Michael P, Ishrat, Tauheed

“…Alzheimer's disease (AD) is the most common form of age-associated dementia characterized by amyloid-β plaques and neurofibrillary tangles. Recent studies have…”
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Enhancement of angiogenesis and neurogenesis by intracerebroventricular injection of secretome from human embryonic stem cell‐derived mesenchymal stem cells in ischemic stroke model by Asgari Taei, Afsaneh, Nasoohi, Sanaz, Hassanzadeh, Gholamreza, Kadivar, Mehdi, Dargahi, Leila, Farahmandfar, Maryam

“…It is well accepted that the success of mesenchymal stem cells (MSCs) therapy against experimental stroke is mainly due to cellular paracrine manners rather…”
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The conditioned medium of human embryonic stem cell‐derived mesenchymal stem cells alleviates neurological deficits and improves synaptic recovery in experimental stroke by Asgari Taei, Afsaneh, Dargahi, Leila, Nasoohi, Sanaz, Hassanzadeh, Gholamreza, Kadivar, Mehdi, Farahmandfar, Maryam

“…The transplantation of mesenchymal stem cells (MSCs) is of main approaches in regenerative therapy for stroke. Due to the potential tumorigenicity and low…”
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Verapamil as an Adjunct Therapy to Reduce tPA Toxicity in Hyperglycemic Stroke: Implication of TXNIP/NLRP3 Inflammasome by Ismael, Saifudeen, Nasoohi, Sanaz, Yoo, Arum, Mirzahosseini, Golnoush, Ahmed, Heba A., Ishrat, Tauheed

“…Thrombolytic therapy has remained quite challenging in hyperglycemic patients for its association with poor prognosis and increased hemorrhagic conversions. We…”
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Thioredoxin interacting protein regulates age-associated neuroinflammation by Ismael, Saifudeen, Nasoohi, Sanaz, Li, Lexiao, Aslam, Khurram S., Khan, Mohammad Moshahid, El-Remessy, Azza B., McDonald, Michael P., Liao, Francesca-Fang, Ishrat, Tauheed

“…Immune system hypersensitivity is believed to contribute to mental frailty in the elderly. Solid evidence indicates NOD-like receptor pyrin domain containing-3…”
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High intensity exercise preconditioning provides differential protection against brain injury following experimental stroke by Rezaei, Rasoul, Nasoohi, Sanaz, Haghparast, Abbas, Khodagholi, Fariba, Bigdeli, Mohammad Reza, Nourshahi, Maryam

“…Different modes of physical activity provide cerebrovascular protection against thromboembolic events. Based on recent reports high intensity exercise…”
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Nanoliposome containing cyclosporine A reduced neuroinflammation responses and improved neurological activities in cerebral ischemia/reperfusion in rat by Partoazar, Alireza, Nasoohi, Sanaz, Rezayat, Sayed M., Gilani, Kambiz, Mehr, Shahram E., Amani, Amir, Rahimi, Nastaran, Dehpour, Ahmad R.

“…Cyclosporine A (CsA) is known as a neuroprotective agent against cerebral ischemia/reperfusion (I/R) in animal models. However, the significant therapeutic…”
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Intra-arterial verapamil improves functional outcomes of thrombectomy in a preclinical model of extended hyperglycemic stroke by Nasoohi, Sanaz, Alehossein, Parsa, Jorjani, Masoumeh, Brown, Candice M, Ishrat, Tauheed

“…The abrupt hyperglycemic reperfusion following thrombectomy has been shown to harm the efficacy of the intervention in stroke patients with large vessel…”
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Thioredoxin-Interacting Protein (TXNIP) in Cerebrovascular and Neurodegenerative Diseases: Regulation and Implication by Nasoohi, Sanaz, Ismael, Saifudeen, Ishrat, Tauheed

“…Neurological diseases, including acute attacks (e.g., ischemic stroke) and chronic neurodegenerative diseases (e.g., Alzheimer’s disease), have always been one…”
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Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke by Ismael, Saifudeen, Zhao, Liang, Nasoohi, Sanaz, Ishrat, Tauheed

“…Activation of the NOD-like receptor protein (NLRP3)-inflammasome has been postulated to mediate inflammatory responses to brain damage during…”
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Reply by Nasoohi, Sanaz, Naderi, Nima

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Paracrine Effects of Mesenchymal Stem Cells in Ischemic Stroke: Opportunities and Challenges by Asgari Taei, Afsaneh, Khodabakhsh, Pariya, Nasoohi, Sanaz, Farahmandfar, Maryam, Dargahi, Leila

“…It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells (MSCs) in ischemic stroke are attributed to their…”
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Metformin-induced protection against oxidative stress is associated with AKT/mTOR restoration in PC12 cells by Khallaghi, Behzad, Safarian, Fatemeh, Nasoohi, Sanaz, Ahmadiani, Abolhassan, Dargahi, Leila

“…Reactive oxygen species have been recognized to impair cell function through suppressing Akt the well-known pro-survival molecule. Pile of concrete evidence…”
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Lost in Translation: Neurotrophins Biology and Function in the Neurovascular Unit by Mirzahosseini, Golnoush, Adam, Justin Mark, Nasoohi, Sanaz, El-Remessy, Azza B., Ishrat, Tauheed

“…The neurovascular unit (NVU) refers to the functional building unit of the brain and the retina, where neurons, glia, and microvasculature orchestrate to meet…”
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Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: Comparison with Memantine by Hemmati, Fatemeh, Dargahi, Leila, Nasoohi, Sanaz, Omidbakhsh, Rana, Mohamed, Zahurin, Chik, Zamri, Naidu, Murali, Ahmadiani, Abolhassan

“…•Protective effect of FTY720, the S1P analog, is compared to Memantine in AD rats.•FTY720 as well as Memantine restores memory in male and female AD…”
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The p75 neurotrophin receptor inhibitor, LM11A-31, ameliorates acute stroke injury and modulates astrocytic proNGF by Nasoohi, Sanaz, Tayefeh Ghahremani, Pargol, Alehossein, Parsa, Elyasizadeh, Siyamak, BaniArdalan, Soha, Ismael, Saifudeen, Vatanpour, Hossein, Ahmadiani, Abolhassan, Ishrat, Tauheed

“…The precursor form of nerve growth factor (proNGF) is essential to maintain NGF survival signaling. ProNGF is also among endogenous ligands for p75…”
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