Search Results - "Nasheuer, H P"

Human Cdc45 is a proliferation‐associated antigen by Pollok, S., Bauerschmidt, C., Sänger, J., Nasheuer, H.‐P., Grosse, F.

“…Cell division cycle protein 45 (Cdc45) plays a critical role in DNA replication to ensure that chromosomal DNA is replicated only once per cell cycle. We…”
Get full text

Phosphorylation of DNA polymerase α-primase by Cyclin A-dependent kinases regulates initiation of DNA replication in vitro by VOITENLEITNER, C, FANNING, E, NASHEUER, H.-P

“…DNA polymerase alpha-primase is the only known eukaryotic enzyme that can start DNA replication de novo. In this study, we investigated the regulation of DNA…”
Get full text

Eukaryotic DNA polymerases, a growing family by Hübscher, U, Nasheuer, H P, Syväoja, J E

“…In eukaryotic cells, DNA polymerases are required to maintain the integrity of the genome during processes, such as DNA replication, various DNA repair events,…”
Get full text

RPA subunit arrangement near the 3′-end of the primer is modulated by the length of the template strand and cooperative protein interactions by Lavrik, Olga I., Kolpashchikov, Dmitry M., Weisshart, Klaus, Nasheuer, Heinz-Peter, Khodyreva, Svetlana N., Favre, Alain

“…To analyze the interaction of human replication protein A (RPA) and its subunits with the DNA template-primer junction in the DNA replication fork, we designed…”
Get full text

Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells by PEARSON, B. E, NASHEUER, H.-P, WANG, T. S.-F

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Functional association of poly(ADP-ribose) polymerase with DNA polymerase α-primase complex: A link between DNA strand break detection and DNA replication by Dantzer, Françoise, de Murcia, Gilbert, Ménissier-de Murcia, Josiane, Nasheuer, Heinz-Peter, Vonesch, Jean-Luc

“…Poly(ADP-ribose) polymerase (PARP) is an element of the DNA damage surveillance network evolved by eukaryotic cells to cope with numerous environmental and…”
Get full text

Quantitative assignment of reaction directionality in constraint-based models of metabolism: Application to Escherichia coli by Fleming, R.M.T., Thiele, I., Nasheuer, H.P.

“…Constraint-based modeling is an approach for quantitative prediction of net reaction flux in genome-scale biochemical networks. In vivo, the second law of…”
Get full text

Control of complex formation of DNA polymerase α–primase and cell‐free DNA replication by the C‐terminal amino acids of the largest subunit p180 by Smith, R.W.P, Nasheuer, H.-P

“…DNA polymerase α–primase is a heterotetrameric complex essential for simian vacuolating virus 40 (SV40) DNA replication. We show that the C‐terminal 67 amino…”
Get full text

Regulation of eukaryotic DNA replication at the initiation step by Pollok, S, Stoepel, J, Bauerschmidt, C, Kremmer, E, Nasheuer, H-P

“…The studies of cell growth and division have remained at the centre of biomedical research for more than 100 years. The combination of genetic, biochemical,…”
Get more information

Integrated stoichiometric, thermodynamic and kinetic modelling of steady state metabolism by Fleming, R.M.T., Thiele, I., Provan, G., Nasheuer, H.P.

“…The quantitative analysis of biochemical reactions and metabolites is at frontier of biological sciences. The recent availability of high-throughput technology…”
Get full text

Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases by Lavrik, Olga I., Nasheuer, Heinz-Peter, Weisshart, Klaus, Wold, Marc S., Prasad, Rajendra, Beard, William A., Wilson, Samuel H., Favre, Alain

“…Human replication protein A (huRPA) is a multisubunit protein which is involved in DNA replication, repair and recombination processes. It exists as a stable…”
Get full text

Interaction of the p70 subunit of RPA with a DNA template directs p32 to the 3′-end of nascent DNA by Kolpashchikov, D.M., Weisshart, K., Nasheuer, H.-P., Khodyreva, S.N., Fanning, E., Favre, A., Lavrik, O.I.

“…Human replication protein A is a heterotrimeric protein involved in various processes of DNA metabolism. To understand the contribution of replication protein…”
Get full text

Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase α by KÜHN, C, MÜLLER, F, MELLE, C, NASHEUER, H.-P, JANUS, F, DEPPERT, W, GROSSE, F

“…Surface plasmon resonance measurements were used for detecting and quantifying protein-protein interactions between the tumor suppressor protein p53, the SV40…”
Get full text

Alternative conformations of human replication protein A are detected by crosslinks with primers carrying a photoreactive group at the 3′-end by Lavrik, O.I., Kolpashchikov, D.M., Nasheuer, H.-P., Weisshart, K., Favre, A.

“…To analyze the influence of single-stranded template extension of DNA duplex on the conformation of human replication protein A (RPA) bound to DNA we have…”
Get full text

Cell cycle-dependent phosphorylation of human DNA polymerase alpha by Nasheuer, H P, Moore, A, Wahl, A F, Wang, T S

“…The expression of DNA polymerase alpha, a principal chromosome replication enzyme, is constitutive during the cell cycle. We show in this report that DNA…”
Get full text

Cell Cycle-Dependent Regulation of Human DNA Polymerase α-Primase Activity by Phosphorylation by Voitenleitner, Christian, Rehfuess, Christoph, Hilmes, Melissa, O'Rear, Lynda, Liao, Pao-Chi, Gage, Douglas A., Ott, Robert, Nasheuer, Heinz-Peter, Fanning, Ellen

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

DNA polymerase alpha-primase from calf thymus. Determination of the polypeptide responsible for primase activity by Nasheuer, H P, Grosse, F

“…Immunoaffinity-purified DNA polymerase alpha-primase complex from calf thymus consists of subunits with molecular weights of 148,000-180,000, 73,000, 59,000,…”
Get full text

A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro by Søe, K, Dianov, G, Nasheuer, H P, Bohr, V A, Grosse, F, Stevnsner, T

“…Several recent studies have shown that human topoisomerase I (htopoI) can recognize various DNA lesions and thereby form a covalent topoisomerase I-DNA…”
Get full text

Two Immunologically Distinct Human DNA Polymerase α-Primase Subpopulations Are Involved in Cellular DNA Replication by Dehde, Silke, Rohaly, Gabor, Schub, Oliver, Nasheuer, Heinz-Peter, Bohn, Wolfgang, Chemnitz, Jan, Deppert, Wolfgang, Dornreiter, Irena

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A cell-free replication system for human polyomavirus JC DNA by Nesper, J, Smith, R W, Kautz, A R, Sock, E, Wegner, M, Grummt, F, Nasheuer, H P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text