Search Results - "Naser, Eyad"

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro[S] by Naser, Eyad, Kadow, Stephanie, Schumacher, Fabian, Mohamed, Zainelabdeen H., Kappe, Christian, Hessler, Gabriele, Pollmeier, Barbara, Kleuser, Burkhard, Arenz, Christoph, Becker, Katrin Anne, Gulbins, Erich, Carpinteiro, Alexander

“…Inhibition of acid sphingomyelinase (ASM), a lysosomal enzyme that catalyzes the hydrolysis of sphingomyelin into ceramide and phosphorylcholine, may serve as…”
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Cell-intrinsic ceramides determine T cell function during melanoma progression by Hose, Matthias, Günther, Anne, Naser, Eyad, Schumacher, Fabian, Schönberger, Tina, Falkenstein, Julia, Papadamakis, Athanasios, Kleuser, Burkhard, Becker, Katrin Anne, Gulbins, Erich, Haimovitz-Friedman, Adriana, Buer, Jan, Westendorf, Astrid M, Hansen, Wiebke

“…Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further…”
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Daratumumab in first-line treatment of patients with light chain amyloidosis and Mayo stage IIIb improves treatment response and overall survival by Oubari, Sara, Hegenbart, Ute, Schoder, Renate, Steinhardt, Maximilian, Papathanasiou, Maria, Rassaf, Tienush, Thimm, Andreas, Hagenacker, Tim, Naser, Eyad, Duhrsen, Ulrich, Reinhardt, Hans C, Kortum, Martin, Agis, Hermine, Schonland, Stefan, Carpinteiro, Alexander

“…Treatment of patients with Mayo stage IIIb light chain (AL) amyloidosis is still challenging, and the prognosis remains very poor. Mayo stage IIIb patients…”
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Dead Cells Induce Innate Anergy via Mertk after Acute Viral Infection by Adomati, Tom, Cham, Lamin B., Hamdan, Thamer A., Bhat, Hilal, Duhan, Vikas, Li, Fanghui, Ali, Murtaza, Lang, Elisabeth, Huang, Anfei, Naser, Eyad, Khairnar, Vishal, Friedrich, Sarah-Kim, Lang, Judith, Friebus-Kardash, Justa, Bergerhausen, Michael, Schiller, Maximilian, Machlah, Yara Maria, Lang, Florian, Häussinger, Dieter, Ferencik, Stanislav, Hardt, Cornelia, Lang, Philipp A., Lang, Karl S.

“…Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such…”
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A Novel Visible Range FRET Probe for Monitoring Acid Sphingomyelinase Activity in Living Cells by Kappe, Christian, Mohamed, Zainelabdeen H., Naser, Eyad, Carpinteiro, Alexander, Arenz, Christoph

“…Activity of acid sphingomyelinase has been implicated in a number of diseases like acute lung injury, sepsis or metastasis of melanoma cells. Here, we present…”
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Impact of time to diagnosis on Mayo stages, treatment outcome, and survival in patients with AL amyloidosis and cardiac involvement by Oubari, Sara, Naser, Eyad, Papathanasiou, Maria, Luedike, Peter, Hagenacker, Tim, Thimm, Andreas, Rischpler, Christoph, Kessler, Lukas, Kimmich, Christoph, Hegenbart, Ute, Schönland, Stefan, Rassaf, Tienush, Reinhardt, Hans Christian, Jöckel, Karl‐Heinz, Dürig, Jan, Dührsen, Ulrich, Carpinteiro, Alexander

“…Objective To study the impact of time to diagnosis on cardiac Mayo stages, treatment outcome, and overall survival. Methods We retrospectively analyzed 77…”
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Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro by Naser, Eyad, Kadow, Stephanie, Schumacher, Fabian, Mohamed, Zainelabdeen H, Kappe, Christian, Hessler, Gabriele, Pollmeier, Barbara, Kleuser, Burkhard, Arenz, Christoph, Becker, Katrin Anne, Gulbins, Erich, Carpinteiro, Alexander

“…Inhibition of acid sphingomyelinase (ASM), a lysosomal enzyme that catalyzes the hydrolysis of sphingomyelin into ceramide and phosphorylcholine, may serve as…”
Get full text