Search Results - "Nascimento Fabris Maeda, Denicar Lina"
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Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model
Published in Proceedings of the National Academy of Sciences - PNAS (04-05-2021)“…As the coronavirus disease 2019 (COVID-19) pandemic rages on, it is important to explore new evolution-resistant vaccine antigens and new vaccine platforms…”
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Dendritic Cell Targeting Using a DNA Vaccine Induces Specific Antibodies and CD4 + T Cells to the Dengue Virus Envelope Protein Domain III
Published in Frontiers in immunology (2019)“…Dengue fever has become a global threat, causing millions of infections every year. An effective vaccine against all four serotypes of dengue virus (DENV) has…”
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LT adjuvant modulates epitope specificity and improves the efficacy of murine antibodies elicited by sublingual vaccination with the N-terminal domain of Streptococcus mutans P1
Published in Vaccine (19-12-2017)“…In this study, we evaluated the immunogenicity, protective efficacy and peptide-based immune signatures of antibodies raised in mice after sublingual…”
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Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope Protein
Published in Frontiers in immunology (25-09-2017)“…The heat-labile toxins (LT) produced by enterotoxigenic display adjuvant effects to coadministered antigens, leading to enhanced production of serum…”
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Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly
Published in PloS one (15-09-2021)“…Objective To describe the neurological and neurodevelopmental outcomes of children with Congenital Zika Syndrome (CZS) associated microcephaly beyond 2 years…”
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Strain-specific transcriptional and posttranscriptional regulation of heat-labile toxin expression by enterotoxigenic Escherichia coli
Published in Brazilian journal of microbiology (01-06-2020)“…Enterotoxigenic Escherichia coli (ETEC) represents one of the most important etiological agents of diarrhea in developing countries and characteristically…”
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Intradermal Delivery of Dendritic Cell-Targeting Chimeric mAbs Genetically Fused to Type 2 Dengue Virus Nonstructural Protein 1
Published in Vaccines (Basel) (01-10-2020)“…Targeting dendritic cells (DCs) by means of monoclonal antibodies (mAbs) capable of binding their surface receptors (DEC205 and DCIR2) has previously been…”
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Minicells from Highly Genome Reduced Escherichia coli: Cytoplasmic and Surface Expression of Recombinant Proteins and Incorporation in the Minicells
Published in ACS synthetic biology (15-10-2021)“…Minicells, small cells lacking a chromosome, produced by bacteria with mutated min genes, which control cell division septum placement, have many potential…”
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Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model
Published in Frontiers in medical technology (30-10-2020)“…Dengue virus represents the main arbovirus affecting humans, but there are no effective drugs or available worldwide licensed vaccine formulations capable of…”
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Corrigendum: Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model
Published in Frontiers in medical technology (27-11-2020)“…[This corrects the article DOI: 10.3389/fmedt.2020.558984.]…”
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